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ACKR1

The protein encoded by this gene is a glycosylated membrane protein and a non-specific receptor for several chemokines. The encoded protein is the receptor for the human malarial parasites Plasmodium vivax and Plasmodium knowlesi. Polymorphisms in this gene are the basis of the Duffy blood group system. Two transcript variants encoding different isoforms have been found for this gene.
Protein class

Blood group antigen proteins, CD markers, G-protein coupled receptors

Predicted location

Membrane

Single cell type specificity

Group enriched (Endothelial cells, Adipocytes)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Group enriched (HEL, HSkMC)

Molecular function

Blood group antigen, G-protein coupled receptor, Receptor, Transducer

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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