Human Anti-ACKR1 Recombinant Antibody (clone ch2C3); Fab Fragment (CAT#: FAMAB-0007CQ-F(E))
Recombinant Human Antibody Fab Fragment clone ch2C3, which is specific to ACKR1. The antibody binds specifcally to the epitope FEDVW of the Duffy receptor.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 High expression in smooth muscle
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16421/36523_B_4_7_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16421/36523_B_4_7_val_selected.jpg
Figure 2 Low expression in kidney
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16421/36523_A_8_5_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16421/36523_A_8_5_val_selected.jpg
Figure 3 Colon
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16421/36523_A_7_3.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16421/36523_A_7_3.jpg
Figure 4 Kidney
(Proximal tubules (microvilli) Staining: Medium Intensity: Moderate)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16421/36523_A_9_5.jpg
(Proximal tubules (microvilli) Staining: Medium Intensity: Moderate)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16421/36523_A_9_5.jpg
Figure 5 Testis
(Leydig cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16421/36523_A_6_6.jpg
(Leydig cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16421/36523_A_6_6.jpg
Figure 6 RNA cell line category: Group enriched (HEL, HSkMC)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000213088-ACKR1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000213088-ACKR1
Specifications
- Immunogen
- CHO cells expressing the recombinant Duffy glycoprotein
- Host Species
- Human
- Derivation
- Chimeric (mouse/human)
- Type
- Chimeric (mouse/human) Fab
- Specificity
- Human ACKR1
- Species Reactivity
- Human
- Clone
- ch2C3
- Applications
- ELISA, FC, Block
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Atypical Chemokine Receptor 1 (Duffy Blood Group); Duffy Blood Group, Atypical Chemokine Receptor; Duffy Blood Group, Chemokine Receptor; Plasmodium Vivax Receptor; Fy Glycoprotein; Glycoprotein D; DARC; GpFy; GPD; FY; Duffy Blood Group Chemokine Receptor; Duffy Antigen/Chemokine Receptor; Atypical Chemokine Receptor 1; Duffy Blood Group Antigen; Duffy Blood Group; CD234 Antigen; CCBP1; CD234; WBCQ1; Dfy
- Gene ID
- 2532
- UniProt ID
- Q16570
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
Single Domain Antibody Products
Rabbit Monoclonal Antibody Products
Fab Antibody Products
ScFv Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1354z | Mouse Anti-ACKR1 Recombinant Antibody (clone 9C5) | WB, ELISA, FC, ICC, IF | Mouse IgG1, κ |
| FAMAB-0007CQ | Human Anti-ACKR1 Recombinant Antibody (clone ch2C3) | ELISA, FC, Block | Chimeric (mouse/human) IgG4, κ |
| FAMAB-0008CQ | Mouse Anti-ACKR1 Recombinant Antibody (clone NaM185-2C3 (2C3)) | ELISA, WB, FC, Block | Mouse IgG1, κ |
| FAMAB-1017CQ | Human Anti-ACKR1 Recombinant Antibody (clone CA52) | Block, SPR, WB, ELISA | Human IgG1 |
| FAMAB-1352CQ | Mouse Anti-ACKR1 Recombinant Antibody (clone Hima-19) | ELISA | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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