Recombinant Anti-CADM1 Vesicular Antibody, EV Displayed (VS-0425-YC247) (CAT#: VS-0425-YC247)

• Application
• ELISA, FC, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• CADM1

• Host Animal
• Human

• Antibody Isotype
• IgG

• Species Reactivity
• Human

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• z domain

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Binding Affinity
• Kd = 0.85 µg/mL

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• Cell adhesion molecule 1

• Biological Process
• Apoptosis, Cell adhesion, Differentiation, Host-virus interaction, Immunity, Spermatogenesis

• Molecular Function
• Developmental protein

• Cellular Localization
• Plasma membrane

• Introduction
• CADM1 (Cell Adhesion Molecule 1) is a Protein Coding gene. Diseases associated with CADM1 include Lung Cancer and Retroperitoneal Fibrosis. Among its related pathways are Cell junction organization and Cell adhesion molecules (CAMs). Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and PDZ domain binding. An important paralog of this gene is CADM2.

• Alternative Names
• BL2, IGSF4, IGSF4A, Necl-2, NECL2, RA175, ST17, SYNCAM, SYNCAM1, TSLC1

• Gene ID
• 23705

• UniProt ID
• Q9BY67

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