Recombinant Anti-CCL5 Vesicular Antibody, EV Displayed (VS-0425-YC572)
CAT#: VS-0425-YC572
The Recombinant Anti-CCL5 Vesicular Antibody, EV Displayed (VS-0425-YC572) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CCL5-expressed cells or tissues. CCL5 (C-C Motif Chemokine Ligand 5) is a protein associated with diseases like ulcer of the lower limbs and periapical granuloma. It plays roles in pathways such as PEDF induced signaling and Toll-like receptor signaling. CCL5 is involved in protein homodimerization and chemokine activity, with an important paralog being CCL3L3.
Gene Expression
Normal Tissue
Figure 1 High expression in bone marrow.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/78447/168177_B_4_4_val_selected.jpg
Normal Tissue
Figure 2 Low expression in skin 1.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/78447/168177_B_7_1_val_selected.jpg
Normal Tissue
Figure 3 Colon
Enterocytes - Mucosal lymphoid cells Staining: Medium Intensity: Strong Quantity: <25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/78447/168177_A_8_3.jpg
Normal Tissue
Figure 4 Kidney
Cells in tubules Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/78447/168177_A_8_5.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (HL-60, NB-4, THP-1, U-937)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000271503-CCL5
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (HL-60, NB-4, THP-1, U-937)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000271503-CCL5
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Inhib, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CCL5
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- C-C motif chemokine ligand 5
- Biological Process
- Chemotaxis, Inflammatory response
- Molecular Function
- Cytokine
- Introduction
- CCL5 (C-C Motif Chemokine Ligand 5) is a Protein Coding gene. Diseases associated with CCL5 include Ulcer Of Lower Limbs and Periapical Granuloma. Among its related pathways are PEDF Induced Signaling and Toll-like receptor signaling pathway. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and chemokine activity. An important paralog of this gene is CCL3L3.
- Alternative Names
- D17S136E, MGC17164, RANTES, SCYA5, SISd, TCP228
- Gene ID
- 6352
- UniProt ID
- P13501
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Related Signaling Pathways
TNF Signaling Pathway
Downloadable Resources
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Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1352z | Mouse Anti-CCL5 Recombinant Antibody (clone 22C12) | ELISA, IHC, WB | Mouse IgG1 |
| HPAB-0378LY | Human Anti-CCL5 Recombinant Antibody (clone 1E4) | ELISA, Inhib | Human IgG1 |
| HPAB-0379LY | Human Anti-CCL5 Recombinant Antibody (clone C8) | ELISA, Inhib | Human IgG1 |
| HPAB-0380LY | Human Anti-CCL5 Recombinant Antibody (clone 1D9) | ELISA, Inhib, FC, IF | Human IgG1 |
| HPAB-0381LY | Human Anti-CCL5 Recombinant Antibody (clone D9) | ELISA, Inhib | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-098CL | Human Anti-CCL5 Recombinant Antibody (TAB-098CL) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0487MZ | Chicken Anti-RANTES Polyclonal IgY | Indirect ELISA, WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-231CQ | Mouse Anti-CCL5 Recombinant Antibody (clone CBL636) | Neut | Mouse IgG2b |
| NEUT-232CQ | Recombinant Mouse Anti-CCL5 Antibody, Unconjugated | ELISA, IHC, Neut | IgG2b |
| NEUT-233CQ | Mouse Anti-CCL5 Recombinant Antibody (clone CBL009) | Neut, WB | Mouse IgG1 |
| NEUT-234CQ | Mouse Anti-CCL5 Recombinant Antibody (clone CBL421) | WB, Neut | Mouse IgG1 |
| NEUT-235CQ | Mouse Anti-CCL5 Recombinant Antibody (clone CBL428) | WB, ELISA(Cap), Neut | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-459CQ | Rat Anti-CCL5 Recombinant Antibody (clone 53405.111) | IF, Inhib | Rat IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0511 | Hi-Affi™ Rabbit Anti-CCL5 Recombinant Antibody (clone DS511AB) | ICC, WB | Rabbit IgG |
| MOR-4545 | Hi-Affi™ Rabbit Anti-CCL5 Recombinant Antibody (clone TH54DS) | WB, IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0378LY-S(P) | Human Anti-CCL5 Recombinant Antibody (clone 1E4); scfv Fragment | ELISA, Inhib | Human scfv |
| HPAB-0379LY-S(P) | Human Anti-CCL5 Recombinant Antibody (clone C8); scfv Fragment | ELISA, Inhib | Human scfv |
| HPAB-0380LY-S(P) | Human Anti-CCL5 Recombinant Antibody (clone 1D9); scfv Fragment | ELISA, Inhib | Human scfv |
| HPAB-0381LY-S(P) | Human Anti-CCL5 Recombinant Antibody (clone D9); scfv Fragment | ELISA, Inhib | Human scfv |
| HPAB-0382LY-S(P) | Human Anti-CCL5 Recombinant Antibody (clone 3E7); scfv Fragment | ELISA, Inhib | Human scfv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0378LY-F(E) | Human Anti-CCL5 Recombinant Antibody (clone 1E4); Fab Fragment | ELISA, Inhib | Human Fab |
| HPAB-0379LY-F(E) | Human Anti-CCL5 Recombinant Antibody (clone C8); Fab Fragment | ELISA, Inhib | Human Fab |
| HPAB-0380LY-F(E) | Human Anti-CCL5 Recombinant Antibody (clone 1D9); Fab Fragment | ELISA, Inhib | Human Fab |
| HPAB-0381LY-F(E) | Human Anti-CCL5 Recombinant Antibody (clone D9); Fab Fragment | ELISA, Inhib | Human Fab |
| HPAB-0382LY-F(E) | Human Anti-CCL5 Recombinant Antibody (clone 3E7); Fab Fragment | ELISA, Inhib | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY69 | Mouse Anti-NHP CCL5 Recombinant Antibody (VS-1024-XY69) | WB, ELISA | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1069 | Anti-CCL5 Immunohistochemistry Kit | IHC |
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