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    CCL5

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    For Research Use Only. Not For Clinical Use.


    Background

    CCL5 (C-C Motif Chemokine Ligand 5) is a Protein Coding gene. Diseases associated with CCL5 include Ulcer Of Lower Limbs and Periapical Granuloma. Among its related pathways are PEDF Induced Signaling and Toll-like receptor signaling pathway. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and chemokine activity. An important paralog of this gene is CCL3L3.
    Protein class

    Cancer-related genes, Human disease related genes, Plasma proteins

    Predicted location

    Membrane, Secreted (different isoforms)

    Single cell type specificity

    Group enriched (NK-cells, dendritic cells, T-cells)

    Immune cell specificity

    Immune cell enhanced (memory CD8 T-cell, gdT-cell)

    Cell line specificity

    Cell line enhanced (HL-60, NB-4, THP-1, U-937)

    Interaction

    Homo and heterooligomers with other chemokines. Interacts with the brown dog tick evasin-4.

    Molecular function

    Cytokine

    More Types Infomation
    Related Signaling Pathways
    TNF Signaling Pathway TNF Signaling Pathway
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