Recombinant Anti-CD226 Vesicular Antibody, EV Displayed (VS-0425-YC693)
CAT#: VS-0425-YC693
The Recombinant Anti-CD226 Vesicular Antibody, EV Displayed (VS-0425-YC693) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CD226-expressed cells or tissues. CD226 facilitates activities like integrin and protein kinase binding, involved in cytokine production regulation by natural killer cells, with human orthologs expressed in embryos.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line HEL
Immunofluorescent staining of human cell line HEL shows localization to plasma membrane & centriolar satellites.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/15865/1847_C10_42_cr5abb48a309a8f_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IHC staining of human tonsil
Immunohistochemical staining of human tonsil shows strong cytoplasmic positivity in cells outside reaction centra.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/15715/ihc_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Neuronal cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/15715/37861_B_7_5.jpg
Normal Tissue
Figure 4 Lymph node
Germinal center cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/15715/37861_A_9_8.jpg
RNA Expression
Figure 5 RNA cell line category: Group enriched (HEL, HMC-1)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000150637-CD226
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CD226
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Mouse
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- CD226 molecule
- Biological Process
- Cell adhesion
- Molecular Function
- Receptor
- Cellular Localization
- Plasma membrane, Nucleoplasm, Centriolar satellite
- Introduction
- Predicted to enable identical protein binding activity; integrin binding activity; and protein kinase binding activity. Acts upstream of or within positive regulation of natural killer cell cytokine production and positive regulation of type II interferon production. Located in external side of plasma membrane. Is expressed in embryo. Orthologous to human CD226 (CD226 molecule).
- Alternative Names
- DNAM-1, DNAM1, Pta1, TLiSA1
- Gene ID
- 225825
- UniProt ID
- Q8K4F0
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "Cd226"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0284CT | Mouse Anti-CD226 Recombinant Antibody (clone EY22), Biotin | FC | Mouse IgG1 |
| MOB-097CQ | Rat Anti-CD226 Recombinant Antibody (MOB-097CQ) | FC, FuncS | Rat IgG2b, κ |
| MOB-008LC | Recombinant Rat Anti-Mouse CD226 Antibody | FC, FuncS | Rat IgG |
| MOB-008LC-S(P) | Recombinant Rat Anti-Mouse CD226 Antibody scFv Fragment | FC, FuncS | Rat IgG |
| MOB-008LC-F(E) | Recombinant Rat Anti-Mouse CD226 Antibody Fab Fragment | FC, FuncS | Rat IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-316CQ | Mouse Anti-CD226 Recombinant Antibody (clone DX11) | FC, FuncS, IP, Block | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-317CQ | Mouse Anti-CD226 Recombinant Antibody (clone CBL052) | WB, Neut | Mouse IgG1 |
| NEUT-318CQ | Mouse Anti-CD226 Recombinant Antibody (clone CBL514) | WB, FC, CyTOF, Neut | Mouse IgG1 |
| NEUT-319CQ | Mouse Anti-CD226 Recombinant Antibody (clone MM0248-1X20) | WB, Neut, IHC-P | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4034 | Hi-Affi™ Rabbit Anti-CD226 Recombinant Antibody (clone SI100DS) | ELISA | Rabbit IgG |
| MOR-4035 | Hi-Affi™ Rabbit Anti-CD226 Recombinant Antibody (clone SI101DS) | ELISA | Rabbit IgG |
| MOR-4036 | Hi-Affi™ Rabbit Anti-CD226 Recombinant Antibody (clone SI102DS) | FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY25 | CytoStream™ Rat Anti-CD226 Recombinant Antibody (clone 10E5) | FC | Rat IgG2b, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1144 | Anti-CD226 Immunohistochemistry Kit | IHC |
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