Recombinant Anti-Cd247 Vesicular Antibody, EV Displayed (VS-0425-YC756) (CAT#: VS-0425-YC756)
The Recombinant Anti-Cd247 Vesicular Antibody, EV Displayed (VS-0425-YC756) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to Cd247-expressed cells or tissues. Cd247 is a protein involved in T cell receptor signaling, with mutations linked to immunodeficiencies, acting as part of the alpha-beta T cell receptor complex.

(Hematopoietic cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8750/27622_B_5_4.jpg

(Germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8750/27622_A_7_8.jpg

(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000198821-CD247
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- Cd247
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Mouse
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Cd247 molecule
- Biological Process
- Adaptive immunity, Host-virus interaction, Immunity
- Molecular Function
- Receptor
- Introduction
- Predicted to enable protein heterodimerization activity; protein homodimerization activity; and protein tyrosine kinase binding activity. Acts upstream of or within T cell receptor signaling pathway and positive regulation of protein localization to cell surface. Located in Golgi apparatus and plasma membrane. Part of alpha-beta T cell receptor complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Human ortholog(s) of this gene implicated in immunodeficiency 25. Orthologous to human CD247 (CD247 molecule).
- Alternative Names
- 4930549J05Rik, A430104F18Rik, Cd3, Cd3-eta, Cd3-zeta, Cd3h, Cd3z, Cd3zeta, T3z, Tcrk, Tcrz
- Gene ID
- 12503
- UniProt ID
- Q3UU54
Downloads
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See other products for "CD247"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-171-F(E) | Recombinant Anti-human CD247 Antibody Fab Fragment | WB, IF, FuncS | Fab |
MHH-171-F(E) | Recombinant Human Anti-human CD247 Antibody Fab Fragment | WB, FC, FuncS | Fab |
FAMAB-0050-YC-F(E) | Mouse Anti-CD247 Recombinant Antibody Fab Fragment (FAMAB-0050-YC-F(E)) | FC, FuncS | Mouse Fab |
FAMAB-0051-YC-F(E) | Mouse Anti-CD247 Recombinant Antibody Fab Fragment (FAMAB-0051-YC-F(E)) | FC, FuncS | Mouse Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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