Recombinant Anti-Cd247 Vesicular Antibody, EV Displayed (VS-0425-YC756)
CAT#: VS-0425-YC756
The Recombinant Anti-Cd247 Vesicular Antibody, EV Displayed (VS-0425-YC756) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to Cd247-expressed cells or tissues. Cd247 is a protein involved in T cell receptor signaling, with mutations linked to immunodeficiencies, acting as part of the alpha-beta T cell receptor complex.
Gene Expression
Normal Tissue
Figure 1 Bone marrow
Hematopoietic cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8750/27622_B_5_4.jpg
Normal Tissue
Figure 2 Lymph node
Germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8750/27622_A_7_8.jpg
RNA Expression
Figure 3 RNA cell line category: Group enriched (HDLM-2, JURKAT, MOLT-4)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000198821-CD247
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- Cd247
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Mouse
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Cd247 molecule
- Biological Process
- Adaptive immunity, Host-virus interaction, Immunity
- Molecular Function
- Receptor
- Introduction
- Predicted to enable protein heterodimerization activity; protein homodimerization activity; and protein tyrosine kinase binding activity. Acts upstream of or within T cell receptor signaling pathway and positive regulation of protein localization to cell surface. Located in Golgi apparatus and plasma membrane. Part of alpha-beta T cell receptor complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Human ortholog(s) of this gene implicated in immunodeficiency 25. Orthologous to human CD247 (CD247 molecule).
- Alternative Names
- 4930549J05Rik, A430104F18Rik, Cd3, Cd3-eta, Cd3-zeta, Cd3h, Cd3z, Cd3zeta, T3z, Tcrk, Tcrz
- Gene ID
- 12503
- UniProt ID
- Q3UU54
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "CD247"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-171-F(E) | Recombinant Anti-human CD247 Antibody Fab Fragment | WB, IF, FuncS | Fab |
| MHH-171-F(E) | Recombinant Human Anti-human CD247 Antibody Fab Fragment | WB, FC, FuncS | Fab |
| FAMAB-0050-YC-F(E) | Mouse Anti-CD247 Recombinant Antibody Fab Fragment (FAMAB-0050-YC-F(E)) | FC, FuncS | Mouse Fab |
| FAMAB-0051-YC-F(E) | Mouse Anti-CD247 Recombinant Antibody Fab Fragment (FAMAB-0051-YC-F(E)) | FC, FuncS | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-171-S(P) | Recombinant Anti-human CD247 Antibody scFv Fragment | WB, IHC, FuncS | scFv |
| MHH-171-S(P) | Recombinant Human Anti-human CD247 Antibody scFv Fragment | FC, Neut, Biosensors, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0546 | Hi-Affi™ Rabbit Anti-CD247 Recombinant Antibody (clone DS546AB) | FC, ICC, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-XY244 | Mouse Anti-CD247 Recombinant Antibody (clone 4D10A6) | ELISA, FC, ICC | Mouse IgG2a |
| VS3-XY246 | Mouse Anti-CD247 Recombinant Antibody (clone 4AOKT3), FITC Conjugated | FC, IHC, IF, WB, ELISA | Mouse IgG2a |
| VS3-XY247 | Mouse Anti-CD247 Recombinant Antibody, APC (clone 4AOKT3) | FC, IHC, IF, WB, ELISA | Mouse IgG2a |
| VS3-XY248 | Mouse Anti-CD247 Recombinant Antibody, FITC (clone 4AOKT3) | FC, IHC, IF, WB, ELISA | Mouse IgG2a |
| VS3-XY249 | Mouse Anti-CD247 Recombinant Antibody, PE (clone 4AOKT3) | FC, IHC, IF, WB, ELISA | Mouse IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC1402 | AbPlus™ Anti-CD247 Magnetic Beads (VS-0724-YC1402) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY28 | CytoStream™ Mouse Anti-CD247 Recombinant Antibody (VS-0225-XY28) | FC | Mouse IgG2a, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY359 | Anti-CD247 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1150 | Anti-Mouse CD247 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1149 | Anti-Human CD247 Immunohistochemistry Kit | IHC |
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