Recombinant Anti-CD36 Vesicular Antibody, EV Displayed (VS-0425-YC24) (CAT#: VS-0425-YC24)
The Recombinant Anti-CD36 Vesicular Antibody, EV Displayed (VS-0425-YC24) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CD36-expressed cells or tissues. The CD36 is a protein crucial for lipid binding and low-density lipoprotein particle binding, associated with conditions like Platelet Glycoprotein IV Deficiency and Malaria, and involved in cytokine signaling pathways.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line HEL
(Immunofluorescent staining of human cell line HEL shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2018/1770_D7_3_selected.jpg
(Immunofluorescent staining of human cell line HEL shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2018/1770_D7_3_selected.jpg
Figure 2 Colon
(Endothelial cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Mucosal lymphoid cells
Staining: Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2018/7436_A_7_3.jpg
(Endothelial cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Mucosal lymphoid cells
Staining: Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2018/7436_A_7_3.jpg
Figure 3 RNA cell line category: Group enriched (ASC diff, HEL)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000135218-CD36
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000135218-CD36
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CD36
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- CD36 molecule
- Biological Process
- Cell adhesion, Lipid transport, Transport
- Molecular Function
- Receptor
- Cellular Localization
- Golgi apparatus
- Introduction
- CD36 (CD36 Molecule) is a Protein Coding gene. Diseases associated with CD36 include Platelet Glycoprotein Iv Deficiency and Malaria. Among its related pathways are Cytokine Signaling in Immune system and Aryl Hydrocarbon Receptor. Gene Ontology (GO) annotations related to this gene include lipid binding and low-density lipoprotein particle binding. An important paralog of this gene is SCARB2.
- Alternative Names
- FAT, GP3B, GP4, GPIV, SCARB3
- Gene ID
- 948
- UniProt ID
- P16671
Related Resources
Insulin Signaling Pathway
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-176-F(E) | Recombinant Anti-human CD36 Antibody Fab Fragment | ELISA, RIA, FuncS | Fab |
| MHH-176-F(E) | Recombinant Human Anti-human CD36 Antibody Fab Fragment | FC, ELISA, FuncS | Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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