Human Anti-CD36 scFv-Fc Chimera (VS-0325-FY39) (CAT#: VS-0325-FY39)

• Host Species
• Human

• Type
• Human IgG1, scFv-Fc

• Specificity
• It was able to specifically bind to both human CD36 and mouse CD36.

• Species Reactivity
• Human, Mouse

• Applications
• ELISA, Inhibition, Flow Cytometry

• Related Disease
• Cancer

• Purity
• >95% as determined by SDS-PAGE

• Concentration
• Please refer to the vial label for the specific concentration.

• Storage
• Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

• Shipping
• Ice packs

• Alternative Names
• CD36 Molecule; CD36 Antigen (Collagen Type I Receptor, Thrombospondin Receptor); CD36 Molecule (Thrombospondin Receptor); Leukocyte Differentiation Antigen CD36; Platelet Glycoprotein IV; Fatty Acid Translocase; Glycoprotein IIIb; PAS IV; GPIIIB; GP3B; GPIV; FAT; GP4

• Gene ID
• 948

• UniProt ID
• P16671

• Long Name
• CD36 Molecule

• Sequence Similarities
• Belongs to the CD36 family.

• Cellular Localization
• Cell membrane; Membrane raft; Golgi apparatus; Apical cell membrane

• Post Translation Modifications
• N-glycosylated and O-glycosylated with a ratio of 2:1.
  Palmitoylated by ZDHHC5.
  Palmitoylation is required for proper localization at the plasma membrane.
  Ubiquitinated at Lys-469 and Lys-472.
  Ubiquitination is induced by fatty acids such as oleic acid and leads to degradation by the proteasome.
  Ubiquitination and degradation are inhibited by insulin which blocks the effect of fatty acids.
  Glycosylation at Asn79, Asn102, Asn134, Asn205, Asn220, Asn163, Asn235, Asn247, Asn321, and Asn417
  Ubiquitination at Lys469 and Lys472
  Modification sites at PhosphoSitePlus
  Glycosylation from GlyConnect CD36_HUMAN (1611)
  Glycosylation from GlyGen

• Protein Refseq
• XP_005250772.1; XP_024302770.1; XP_024302771.1; XP_047276997.1; XP_047276998.1

• Function
• CD36 is a multifunctional membrane protein involved in various biological processes, including fatty acid uptake, thrombospondin binding, and cellular adhesion. It plays a role in lipid metabolism, angiogenesis, and inflammation, and is implicated in diseases such as atherosclerosis and diabetes.

Isotype Control

• MOB-200CQ
• Human IgG Fc Isotype Control Antibody

Secondary Antibody

• 2ND-029CQ
• Goat Anti-Human IgG Fc Antibody

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