Human Anti-CD36 scFv-Fc Chimera (VS-0325-FY39)
CAT#: VS-0325-FY39
The anti-CD36 scFv-Fc antibody targets CD36, a scavenger receptor involved in lipid metabolism and immune responses. It is designed to modulate CD36 function, which may have therapeutic implications in atherosclerosis and other lipid-related disorders.



Specifications
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Specificity
- It was able to specifically bind to both human CD36 and mouse CD36.
- Species Reactivity
- Human, Mouse
- Applications
- ELISA, Inhibition, Flow Cytometry
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- CD36 Molecule; CD36 Antigen (Collagen Type I Receptor, Thrombospondin Receptor); CD36 Molecule (Thrombospondin Receptor); Leukocyte Differentiation Antigen CD36; Platelet Glycoprotein IV; Fatty Acid Translocase; Glycoprotein IIIb; PAS IV; GPIIIB; GP3B; GPIV; FAT; GP4
- Gene ID
- 948
- UniProt ID
- P16671
- Long Name
- CD36 Molecule
- Sequence Similarities
- Belongs to the CD36 family.
- Cellular Localization
- Cell membrane; Membrane raft; Golgi apparatus; Apical cell membrane
- Post Translation Modifications
- N-glycosylated and O-glycosylated with a ratio of 2:1.
Palmitoylated by ZDHHC5.
Palmitoylation is required for proper localization at the plasma membrane.
Ubiquitinated at Lys-469 and Lys-472.
Ubiquitination is induced by fatty acids such as oleic acid and leads to degradation by the proteasome.
Ubiquitination and degradation are inhibited by insulin which blocks the effect of fatty acids.
Glycosylation at Asn79, Asn102, Asn134, Asn205, Asn220, Asn163, Asn235, Asn247, Asn321, and Asn417
Ubiquitination at Lys469 and Lys472
Modification sites at PhosphoSitePlus
Glycosylation from GlyConnect CD36_HUMAN (1611)
Glycosylation from GlyGen
- Protein Refseq
- XP_005250772.1; XP_024302770.1; XP_024302771.1; XP_047276997.1; XP_047276998.1
- Function
- CD36 is a multifunctional membrane protein involved in various biological processes, including fatty acid uptake, thrombospondin binding, and cellular adhesion. It plays a role in lipid metabolism, angiogenesis, and inflammation, and is implicated in diseases such as atherosclerosis and diabetes.
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Related Signaling Pathways
Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
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