Human Anti-CD36 scFv-Fc Chimera (VS-0325-FY39) (CAT#: VS-0325-FY39)
The anti-CD36 scFv-Fc antibody targets CD36, a scavenger receptor involved in lipid metabolism and immune responses. It is designed to modulate CD36 function, which may have therapeutic implications in atherosclerosis and other lipid-related disorders.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line HEL
(Immunofluorescent staining of human cell line HEL shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2018/1770_D7_3_selected.jpg
(Immunofluorescent staining of human cell line HEL shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2018/1770_D7_3_selected.jpg
Figure 2 Colon
(Endothelial cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Mucosal lymphoid cells
Staining: Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2018/7436_A_7_3.jpg
(Endothelial cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Mucosal lymphoid cells
Staining: Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2018/7436_A_7_3.jpg
Figure 3 RNA cell line category: Group enriched (ASC diff, HEL)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000135218-CD36
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000135218-CD36
Specifications
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Specificity
- It was able to specifically bind to both human CD36 and mouse CD36.
- Species Reactivity
- Human, Mouse
- Applications
- ELISA, Inhibition, Flow Cytometry
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- CD36 Molecule; CD36 Antigen (Collagen Type I Receptor, Thrombospondin Receptor); CD36 Molecule (Thrombospondin Receptor); Leukocyte Differentiation Antigen CD36; Platelet Glycoprotein IV; Fatty Acid Translocase; Glycoprotein IIIb; PAS IV; GPIIIB; GP3B; GPIV; FAT; GP4
- Gene ID
- 948
- UniProt ID
- P16671
- Long Name
- CD36 Molecule
- Sequence Similarities
- Belongs to the CD36 family.
- Cellular Localization
- Cell membrane; Membrane raft; Golgi apparatus; Apical cell membrane
- Post Translation Modifications
- N-glycosylated and O-glycosylated with a ratio of 2:1.
Palmitoylated by ZDHHC5.
Palmitoylation is required for proper localization at the plasma membrane.
Ubiquitinated at Lys-469 and Lys-472.
Ubiquitination is induced by fatty acids such as oleic acid and leads to degradation by the proteasome.
Ubiquitination and degradation are inhibited by insulin which blocks the effect of fatty acids.
Glycosylation at Asn79, Asn102, Asn134, Asn205, Asn220, Asn163, Asn235, Asn247, Asn321, and Asn417
Ubiquitination at Lys469 and Lys472
Modification sites at PhosphoSitePlus
Glycosylation from GlyConnect CD36_HUMAN (1611)
Glycosylation from GlyGen
- Protein Refseq
- XP_005250772.1; XP_024302770.1; XP_024302771.1; XP_047276997.1; XP_047276998.1
- Function
- CD36 is a multifunctional membrane protein involved in various biological processes, including fatty acid uptake, thrombospondin binding, and cellular adhesion. It plays a role in lipid metabolism, angiogenesis, and inflammation, and is implicated in diseases such as atherosclerosis and diabetes.
Recommended Products
Isotype Control
Secondary Antibody
Related Resources
Insulin Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "CD36"
Select a product category from the dropdown menu below to view related products.
Please select product type
IgG Antibody Products
Fab Antibody Products
ScFv Antibody Products
Blocking Antibody Products
IgM Antibody Products
Neutralizing Antibody Products
Rabbit Monoclonal Antibody Products
Cancer Stem Cell Biomarker Specific Antibody Products
Flow Cytometry (FC) related Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-176 | Recombinant Anti-human CD36 Antibody | WB, ELISA, IHC, FuncS | IgG |
| MHH-176 | Recombinant Human Anti-human CD36 Antibody | ELISA, FacS, FuncS | IgG |
| MOB-0491CT | Mouse Anti-CD36 Recombinant Antibody (clone 296-2H3) | Block, FC, IF, IHC-Fr | Mouse IgG2a |
| MRO-0298-CN | Rabbit Anti-CD36 Recombinant Antibody (clone CBACN-114) | WB, IF, IHC, IP, FC | Rabbit IgG |
| VS3-CJ705 | Rabbit Anti-CD36 Recombinant Antibody (VS3-CJ705) | WB, ICC, IF, IHC, IP, FC | Rabbit IgG |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for VS-0325-FY39. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: ELISA, IP, FC, FuncS, Neut, IF, WB
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: FuncS, IF, Neut, ELISA, FC, IP, ICC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: WB, FuncS, IF, Neut, ELISA, FC, IP
Application: FC, IP, ELISA, Neut, FuncS, IF, ICC
Application: ELISA, FC, IF, WB
Application: WB, ELISA, FC, IHC, IF, IP
Application: ELISA, PD, Activ, PK, Stim
-1.jpg)
Application: FC, FuncS, IA, IF, IP, IHC
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
