Recombinant Anti-CD96 Vesicular Antibody, EV Displayed (VS-0425-YC682)

CAT#: VS-0425-YC682

The Recombinant Anti-CD96 Vesicular Antibody, EV Displayed (VS-0425-YC682) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CD96-expressed cells or tissues. CD96 acts in the regulation of natural killer cell cytokine production and interferon production, expressed in various tissues including the central nervous system and heart.

Gene Expression
Figure 1 Small intestine Figure 2 Lymph node Figure 3 Spleen Figure 4 RNA cell line category: Cell line enhanced (HEL, JURKAT, MOLT-4, RT4, U-937)

Recombinant Antibody

  • Application
  • Block, ELISA, FC, Cell-uptake
  • Product Type
  • Ab-Fc-EVs
  • Antibody Quantification (Ab/EV)
  • ~100 Ab/EV
  • Target
  • CD96
  • Host Animal
  • Mouse
  • Antibody Isotype
  • IgG
  • Species Reactivity
  • Mouse
  • Expression Cell
  • Mammalian cell

Engineered EVs

  • EV-sorting domain
  • CD63
  • Fc-binding domain
  • Protein A
  • EV Size
  • 30~150 nm
  • Producing Cell
  • HEK293F
  • Isolation Method
  • Gradient centrifugation
  • Purification
  • qEV size exclusion chromatography
  • Concentration
  • 1 x 10¹⁰
  • Size
  • 1 mL
  • Buffer
  • PBS
  • Storage
  • Store at -80°C for 12 months

Target

  • Full Name
  • CD96 molecule
  • Biological Process
  • Cell adhesion
  • Introduction
  • Acts upstream of or within negative regulation of natural killer cell cytokine production; negative regulation of type II interferon production; and response to lipopolysaccharide. Predicted to be located in cytoplasm. Is expressed in several structures, including blood; central nervous system; ganglia; heart; and lung. Human ortholog(s) of this gene implicated in C syndrome. Orthologous to human CD96 (CD96 molecule).
  • Alternative Names
  • 1700109I12Rik, Tactile
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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