+ Filter
Loading...
Custom Services order now ship next day

CD96

Anti-CD96 Recombinant Antibody Products

More Infomation

Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag

More Infomation

Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us

For Research Use Only. Not For Clinical Use.


Creative Biolabs provides an extensive array of high-quality anti-CD96 antibodies for a variety of research purposes. Our antibodies are rigorously validated and supported by expert technical services. With a focus on efficacy and accuracy, Creative Biolabs empowers researchers to advance their projects in diverse research fields.

CD96: An Effective Target for Cancer Immunotherapy

CD96, a member of the immunoglobulin superfamily, is a critical regulator of immune cell function. It interacts with nectin and nectin-like proteins and, in conjunction with TIGIT, acts as a co-inhibitory receptor for CD226. This regulatory mechanism suggests that CD96 and TIGIT might represent helpful targets for cancer immunotherapy. Recent studies have demonstrated CD96's significance in modulating the activity of NK cells and CD8+ T cells, highlighting its pivotal role in tumor immune surveillance. Targeting CD96 may offer novel therapeutic avenues for cancer treatment.

Alternative Names

Cell surface antigen CD96; Cluster of Differentiation 96; T cell activation; Tactile; T-cell surface protein tactile.

Background

The protein encoded by this gene belongs to the immunoglobulin superfamily. It is a type I membrane protein. The protein may play a role in the adhesive interactions of activated T and NK cells during the late phase of the immune response. It may also function in antigen presentation. Alternative splicing generates multiple transcript variants encoding distinct isoforms.

Protein class

CD markers, Disease related genes, Human disease related genes

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Group enriched (T-cells, dendritic cells, NK-cells)

Immune cell specificity

Group enriched (MAIT T-cell, memory CD8 T-cell, naive CD8 T-cell, NK-cell, gdT-cell, naive CD4 T-cell, memory CD4 T-cell, T-reg)

Cell line specificity

Cell line enhanced (HEL, JURKAT, MOLT-4, RT4, U-937)

Interaction

Homodimer; disulfide-linked. Interacts with PVR.

More Types Infomation

Anti-CD96 rAb Products

Creative Biolabs, a prominent antibody developer, provides a broad spectrum of high-quality anti-CD96 antibodies. These antibodies are meticulously developed and validated to meet the stringent requirements of researchers worldwide, ensuring exceptional performance and reliability in various applications.

Table 1. Featured anti-CD96 recombinant antibody products at Creative Biolabs.

Cat. No. Product Name Target Species Host Species Applications
NEUT-439CQ Rat Anti-Cd96 Recombinant Antibody (clone 3.3) Mouse Rat IgG1, κ FC, Block
NEUT-438CQ Mouse Anti-CD96 Recombinant Antibody (clone NK92.39) Human Mouse IgG1 Block, FuncS, FC
MOB-0526CT Recombinant Mouse anti-Human CD96 Monoclonal antibody (EML1037) Human Mouse WB
VS-0723-WK163 Human Anti-CD96 Recombinant Antibody (VS-0723-WK163) Human Human Chimeric (rabbit/human) IgG1 FC
CBPAB-601NL Recombinant Anti-human CD96 Antibody Human Rabbit WB, IHC-P, IHC-Fr: 1:100-1:500
P-ELISA: 1:500-1:1000

Creative Quality Control

At Creative Biolabs, we are committed to providing high-quality recombinant anti-CD96 antibodies to assist with your immunological research. Our cutting-edge facilities and continuous dedication to quality ensure that our antibodies are superior. Our trained scientists rigorously monitor every stage of the manufacturing process, constantly developing our processes to ensure the highest standards of biotechnological innovation.

Customer Reviews

Excellent
Va***e
Rat Anti-Cd96 Recombinant Antibody (clone 3.3) (NEUT-439CQ)
I've been using Creative Biolabs' anti-CD96 antibody for my flow cytometry experiments, and I'm extremely impressed with its performance. The antibody consistently provides clear and distinct staining of CD96-positive cells, even at low concentrations. The background staining is minimal, allowing for accurate quantification of target cell populations. A great experience!
21/Mar/2022
Excellent
Ca***y
Mouse Anti-CD96 Recombinant Antibody (clone NK92.39) (NEUT-438CQ)
I've had excellent results using Creative Biolabs' anti-CD96 antibody in my functional studies. The antibody has allowed me to effectively block CD96 signaling, providing crucial insights into its role in T cell activation and immune responses. The antibody's low non-specific binding has been essential for obtaining reliable and interpretable data.
13/May/2022
Excellent
Ev***n
Recombinant Mouse anti-Human CD96 Monoclonal antibody (EML1037) (MOB-0526CT)
Creative Biolabs' anti-CD96 antibody has consistently performed well in my Western Blot experiments. The antibody has demonstrated high sensitivity and specificity for CD96 detection, even in complex biological samples. The minimal background signal has facilitated accurate quantification of protein expression levels.
27/Oct/2023

rAb Production

Our cutting-edge approach utilizes genetically modified cells to produce highly selective anti-CD96 recombinant antibodies. This improved method offers efficient and adaptable manufacturing, ensuring a constant supply for plenty of applications.

Featured Anti-CD96 Recombinant Antibody Production PlatformsFig.1 Milligram-scale. (Creative Biolabs Original)
Fig.1 Milligram-scale anti-CD96 recombinant antibody production.

Fig.2 Gram-scale. (Creative Biolabs Original)Fig.2 Gram-scale anti-CD96 recombinant antibody production.

rAb Modalities

Creative Biolabs offers a wide range of high-quality anti-CD96 recombinant antibodies in a variety of formats to meet your diverse experimental needs. Whether for immunoprecipitation, Western blot, or immunofluorescence, we have the capacity to provide the antibody products you need.

Fig.3 CD96 antibody production and modalities. (Creative Biolabs Original)Fig.3 Full-length anti-CD96 recombinant antibody production and modalities.

CD96-Targeted Drug Information

Table 2. Public drug targeting CD96.

Highest Phase Mechanism of Action Product Category Condition Organization
Phase II Anti-CD96 (T-Cell Surface Protein Tactile) Cancer Immunotherapy
Human Monoclonal Antibodies
Cancer, head and neck (squamous cell carcinoma)
Cancer, lung (non-small cell) (NSCLC)
Cancer, solid tumor
GlaxoSmithKline (GSK)
GSK (Originator)
Phase I Anti-PVR (Poliovirus Receptor; CD155)
Drugs Targeting DNAX Accessory Molecule 1 (DNAM-1; CD226)
Drugs Targeting T-Cell Surface Protein Tactile (CD96)
Immune Checkpoint Inhibitors
TIGIT/Poliovirus Receptor (PVR; CD155) Interaction Inhibitors
Cancer Immunotherapy
Humanized Monoclonal Antibodies
Cancer, solid tumor
Multiple myeloma
Nectin Therapeutics (Originator)
Biological Testing Anti-CD96 (T-Cell Surface Protein Tactile)
Anti-TIGIT (T-Cell Immunoreceptor with Ig and ITIM domains; VSIG9)
Immune Checkpoint Inhibitors
Bispecific Antibodies
Cancer Immunotherapy
Murine Monoclonal Antibodies
Cancer Agenus (Originator)
Biological Testing Anti-CD96 (T-Cell Surface Protein Tactile)
Anti-PDCD1 (Programmed Cell Death Protein 1; PD-1) (delta42PD1 Splicing Isoform)
Immune Checkpoint Inhibitors
Bispecific Antibody Fusions
Cancer Immunotherapy
Fusion Proteins
Polypeptides, from 41 AA
Single-Chain V-Domain Antibody Fragment (scFv)
Cancer Chongqing Precision Biotech (Originator)
Biological Testing Anti-CD96 (T-Cell Surface Protein Tactile)
Anti-PDCD1 (Programmed Cell Death Protein 1; PD-1) (delta42PD1 Splicing Isoform)
Immune Checkpoint Inhibitors
Bispecific Antibody Fusions
Cancer Immunotherapy
Fc Fusion Proteins
Polypeptides, from 41 AA
Single-Chain V-Domain Antibody Fragment (scFv)
Cancer Chongqing Precision Biotech (Originator)
Biological Testing Drugs Targeting T-Cell Surface Protein Tactile (CD96) Cancer Immunotherapy
Chimeric Antigen Receptor (CAR)-Modified Natural Killer (NK) Cells
Cancer ONK Therapeutics (Originator)
Biological Testing Anti-CD96 (T-Cell Surface Protein Tactile) Cancer Immunotherapy
Humanized Monoclonal Antibodies
Cancer
Infection, viral
23andMe (Originator)
Biological Testing Fc Fusion Proteins
Polypeptides, from 41 AA
Systemic lupus erythematosus Fengchao Pharmaceutical Technol Shanghai (Originator)

(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)

Creative Biolabs provides a wide choice of high-quality anti-CD96 antibodies that are precisely produced to match your stringent requirements. Our dedication to quality guarantees that your findings are powered by the most dependable tools available. Contact us immediately to maximize the possibilities of your study.

  • 0
  • 0
Cart
    Go to compare

    Go to compare