Recombinant Anti-CDCP1 Vesicular Antibody, EV Displayed (VS-0425-YC160) (CAT#: VS-0425-YC160)
The Recombinant Anti-CDCP1 Vesicular Antibody, EV Displayed (VS-0425-YC160) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CDCP1-expressed cells or tissues. The CDCP1 is a protein involved in pathways like Wnt / Hedgehog / Notch and NF-kappaB Signaling, associated with colorectal cancer.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 High expression in esophagus
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10978/28098_B_5_1_val_selected.jpg
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10978/28098_B_5_1_val_selected.jpg
Figure 2 Kidney
(Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10979/28106_A_7_5.jpg
(Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10979/28106_A_7_5.jpg
Figure 3 Testis
(Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10979/28106_A_5_6.jpg
(Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10979/28106_A_5_6.jpg
Figure 4 Prostate
(Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10979/28106_A_3_5.jpg
(Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10979/28106_A_3_5.jpg
Figure 5 Colon
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10979/28106_A_7_3.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10979/28106_A_7_3.jpg
Figure 6 Liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10979/28106_A_7_4.jpg
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10979/28106_A_7_4.jpg
Figure 7 RNA cell line category: Cell line enhanced.
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000163814-CDCP1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000163814-CDCP1
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CDCP1
- Host Animal
- Human
- Antibody Isotype
- IgG1
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- CUB domain containing protein 1
- Cellular Localization
- Nucleoplasm, Vesicles, Nuclear bodies
- Introduction
- CDCP1 (CUB Domain Containing Protein 1) is a Protein Coding gene. Diseases associated with CDCP1 include Colorectal Cancer. Among its related pathways are Wnt / Hedgehog / Notch and NF-kappaB Signaling.
- Alternative Names
- CD318, SIMA135
- Gene ID
- 64866
- UniProt ID
- Q9H5V8
Downloads
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Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2604z | Mouse Anti-CDCP1 Recombinant Antibody (clone 40A11) | WB, ELISA, FC, ICC, IHC | Mouse IgG1 |
| MRO-0400-CN | Mouse Anti-CDCP1 Recombinant Antibody (clone B2-E6) | WB, IHC, IF | Mouse IgG1 |
| HPAB-1060-FY | Human Anti-CDCP1 Recombinant Antibody (clone 65E8) | ELISA, FC | Human IgG |
| VS3-WK135 | Mouse Anti-CDCP1 Recombinant Antibody (clone G3-H11) | WB, ELISA | Mouse IgG1 |
| VS7-HM665 | Mouse Anti-CDCP1 Recombinant Antibody (clone 5G3H11) | IHC | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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