Anti-Human CDCP1 Recombinant Antibody (ch25A11) (CAT#: TAB-404LC)
This product is a recombinant mouse antibody that recognizes CDCP1. The antibody is internalized after binding and can kill PC-3 cells during in vitro transplantation and invasion in vitro. antibody treatment at 0.8 μM resulted in a 78% inhibition of PC-3 cell migration compared to the PBS/complete medium control.
Specific Inquiry
FC
Figure 1 FACS profile of chimeric 25Al 1 IgG on PC-3, DuI 45 cell lines.
LN met is lymph node metastasis. GFI is the geometric mean of fluorescence intensity.
IHC
Figure 2 IHC staining of 25Al 1 on 1 : PC-3 cells, secondary alone (negative control), 2: PC-3 cells (positive control), 3: Patient 2, benign glands, 4: Patient 2, malignant glands, 5: Patient 5, benign glands, 6: Patient 5, malignant glands.
FuncS
Figure 3 Summary of cell migration and invasion assays. PC-3 cells were treated with titrations of ch25Al 1 or CUBl, or 2.5 μM of PP2 and tested in Boyden chambers for inhibition of cell migration and invasion.
FuncS
Figure 4 shows the internalization assay using anti-CDCPl antibodies with appropriate saporin secondary conjugates, or with ch25Al 1-Sap direct conjugate.
FuncS
Figure 5 Effect of ch25Al 1 -saporin direct conjugate on PC-3 tumor growth.
Specifications
- Host Species
- Human
- Derivation
- Chimeric (Mouse/human)
- Type
- Chimeric antibody (mouse/human)
- Specificity
- Human
- Clone
- ch25A11
- Applications
- FC, FuncS, IHC
- Related Disease
- Prostate cancer
Applications
- Application Notes
- This antibody has been reported for use in Flow Cytometry, Functional Assay, Immunohistochemistry.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone ch25A11"
See other products for "CDCP1"
Select a product category from the dropdown menu below to view related products.
Please select product type
Humanized Antibody Products
Mouse Antibody Products
Chimeric Antibody Products
Rabbit Monoclonal Antibody Products
Fab Antibody Products
IgG Antibody Products
ScFv Antibody Products
Flow Cytometry (FC) related Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-149CL | Human Anti-CDCP1 Recombinant Antibody (TAB-149CL) | FuncS | Human IgG |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for TAB-404LC. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: Neut, ELISA, IF, IP, FuncS, FC, IHC
Application: ELISA, IP, FC, FuncS, Neut, IF, WB
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: WB, FuncS, IF, Neut, ELISA, FC, IP
Application: ELISA, IHC
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: FuncS, IF, Neut, ELISA, FC, IP, WB
Application: ELISA, IHC, FC, IP, IF, Inhib
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: ELISA, FC, Inhib, FuncS
Application: FC, IA, IF, IP, IHC, FuncS
Application: ELISA, Vaccine, FuncS
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
