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CDCP1

Anti-CDCP1 Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


CDCP1 is a transmembrane protein expressed on various cell types, including cancer cells, where it is associated with tumor progression, metastasis, and immune evasion. CDCP1 plays a role in cell adhesion, migration, and survival, particularly in the context of epithelial cells and cancer cells. It has been shown to regulate cell signaling pathways that influence cell shape, motility, and invasive behavior, contributing to cancer metastasis. CDCP1's overexpression is linked to poor prognosis in several cancers, and it is considered a potential therapeutic target for anti-cancer therapies aimed at inhibiting tumor metastasis and promoting immune responses against tumors.
Protein class

CD markers

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (Pancreatic endocrine cells, Basal keratinocytes, Urothelial cells, Basal respiratory cells)

Immune cell specificity

Immune cell enhanced (NK-cell, myeloid DC)

Cell line specificity

Cell line enhanced

Interaction

Interacts with CDH2/N-cadherin, CDH3/P-cadherin, SDC1/syndecan-1, SDC4/syndecan-4 and the serine protease ST14/MT-SP1. Also interacts with SRC and PRKCG/protein kinase C gamma.

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