Anti-Human CDCP1 Recombinant Antibody (25A11) (CAT#: TAB-403LC)
Recombinant monoclonal antibody to CDCP1. 25A11 is a mouse monoclonal antibody that can be potentially used in the treatment of prostate cancer.
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
Figure 1 FACS profile of chimeric 25Al 1 IgG on PC-3, DuI 45 cell lines.
LN met is lymph node metastasis. GFI is the geometric mean of fluorescence intensity.
Figure 2 IHC staining of 25Al 1 on 1 : PC-3 cells, secondary alone (negative control), 2: PC-3 cells (positive control), 3: Patient 2, benign glands, 4: Patient 2, malignant glands, 5: Patient 5, benign glands, 6: Patient 5, malignant glands.
Figure 3 Summary of cell migration and invasion assays. PC-3 cells were treated with titrations of ch25Al 1 or CUBl, or 2.5 μM of PP2 and tested in Boyden chambers for inhibition of cell migration and invasion.
Figure 4 shows the internalization assay using anti-CDCPl antibodies with appropriate saporin secondary conjugates, or with ch25Al 1-Sap direct conjugate.
Figure 5 Effect of ch25Al 1 -saporin direct conjugate on PC-3 tumor growth.
Specifications
- Host Species
- Mouse
- Derivation
- Phage display antibody
- Specificity
- Human
- Clone
- 25A11
- Applications
- FC, FuncS, IHC
- Related Disease
- Prostate cancer
Applications
- Application Notes
- This antibody has been reported for use in Flow Cytometry, Functional Assay, Immunohistochemistry.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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See other products for "Clone 25A11"
See other products for "CDCP1"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-2604z | Mouse Anti-CDCP1 Recombinant Antibody (clone 40A11) | WB, ELISA, FC, ICC, IHC | Mouse IgG1 |
HPAB-1060-FY | Human Anti-CDCP1 Recombinant Antibody (clone 65E8) | ELISA, FC | Human IgG |
HPAB-1061-FY | Human Anti-CDCP1 Recombinant Antibody (clone 79C12) | ELISA, FC | Human IgG |
HPAB-1062-FY | Human Anti-CDCP1 Recombinant Antibody (clone 23E9) | ELISA, FC | Human IgG |
HPAB-1063-FY | Human Anti-CDCP1 Recombinant Antibody (clone 36C1) | ELISA, FC | Human IgG |
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To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# TAB-403LC, RRID: AB_3111926)
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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