Recombinant Anti-Cx3cr1 Vesicular Antibody, EV Displayed (VS-0425-YC41) (CAT#: VS-0425-YC41)

• Application
• ELISA, FC, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• Cx3cr1

• Host Animal
• Mouse

• Antibody Isotype
• IgG

• Species Reactivity
• Mouse

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• Protein A

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• C-X3-C motif chemokine receptor 1

• Biological Process
• Adaptive immunity, Host-virus interaction, Immunity, Inflammatory response, Innate immunity

• Molecular Function
• G-protein coupled receptor, Receptor, Transducer

• Cellular Localization
• Plasma membrane

• Introduction
• Enables C-X3-C chemokine binding activity and C-X3-C chemokine receptor activity. Involved in several processes, including antifungal innate immune response; central nervous system development; and synapse organization. Located in cell surface. Is expressed in several structures, including brain; colon; genitourinary system; head mesenchyme; and meninges. Used to study age related macular degeneration 12. Human ortholog(s) of this gene implicated in several diseases, including human immunodeficiency virus infectious disease; obesity; pulmonary hypertension; retinal disease (multiple); and systemic scleroderma. Orthologous to human CX3CR1 (C-X3-C motif chemokine receptor 1).

• Alternative Names
• mCX3CR1

• Gene ID
• 13051

• UniProt ID
• Q9Z0D9

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