Recombinant Chicken Anti-CyRPA Antibody (clone Cy.004) (CAT#: VS-0923-XY5)

This is a recombinant chicken antibody clone Cy.004 specific for cysteine rich protective antigen (CyRPA). This antibody reduced parasite growth in vitro growth inhibition activity.


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  • Published Data
  • Datasheet
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SPR

Figure 1 Kinetic parameters for the binding of antibody to CyRPA, as determined by surface plasmon resonance analysis.

Figure 1 Kinetic parameters for the binding of antibody to CyRPA, as determined by surface plasmon resonance analysis.

The Kd value of Cy.004 against CyRPA is 2.8 μM.

Inhib

Figure 2 In vitro growth inhibitory activity (GIA) of antibody against the 3D7 clone of <em>P. falciparum</em> at 0.5 mg/ml.

Figure 2 In vitro growth inhibitory activity (GIA) of antibody against the 3D7 clone of P. falciparum at 0.5 mg/ml.

The Cy.004 antibody reduced parasite growth by 80%.


Specifications

  • Immunogen
  • Recombinant CyRPA in complete or incomplete Freund's adjuvant
  • Host Species
  • Chicken
  • Type
  • Chicken IgY
  • Specificity
  • CyRPA
  • Species Reactivity
  • P. falciparum
  • Clone
  • Cy.004
  • Applications
  • ELISA, SPR, Inhib
  • Related Disease
  • Malaria

Product Property

  • Purification
  • Protein G affinity purified
  • Purity
  • >95%
  • Format
  • Liquid
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • ELISA: 10 μg/mL
    Inhibition assayition: Cy.004 Inhibited growth with EC50 values of 170 μg/mL.

Target

  • Alternative Names
  • Cysteine rich protective antigen

Recommended Products

Recommended Dilution Buffer

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "CyRPA"

Recombinant Antibody

CAT Product Name Application Type
PABC-476 Recombinant Mouse Anti-CyRPA Antibody (8A7) IB, Inhib, ELISA, WB Mouse IgG1, κ
VS-0923-XY6 Recombinant Mouse Anti-CyRPA Antibody (clone Cy.002) ELISA, SPR Mouse IgG

Fab Fragment Antibody

CAT Product Name Application Type
PFBC-476 Recombinant Mouse Anti-CyRPA Antibody Fab Fragment (8A7) ELISA, WB, Inhib Mouse Fab

scFv Fragment Antibody

CAT Product Name Application Type
PSBC-476 Recombinant Mouse Anti-CyRPA Antibody scFv Fragment (8A7) ELISA, WB, Inhib Mouse scFv

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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