Recombinant Anti-DAG1 Vesicular Antibody, EV Displayed (VS-0425-YC302) (CAT#: VS-0425-YC302)

• Application
• ELISA, FC, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• DAG1

• Host Animal
• Mouse

• Antibody Isotype
• IgG

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• Protein A

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• Dystroglycan 1

• Biological Process
• Host-virus interaction

• Molecular Function
• Host cell receptor for virus entry, Receptor

• Cellular Localization
• Vesicles, Plasma membrane, Nucleoplasm

• Introduction
• This gene encodes dystroglycan, a central component of dystrophin-glycoprotein complex that links the extracellular matrix and the cytoskeleton in the skeletal muscle. The encoded preproprotein undergoes O- and N-glycosylation, and proteolytic processing to generate alpha and beta subunits. Certain mutations in this gene are known to cause distinct forms of muscular dystrophy. Alternative splicing results in multiple transcript variants, all encoding the same protein. [provided by RefSeq, Nov 2015]

• Alternative Names
• 156DAG, A3a, AGRNR, DAG

• Gene ID
• 1605

• UniProt ID
• Q14118

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