Recombinant Anti-DLK1 Vesicular Antibody, EV Displayed (VS-0425-YC213)
CAT#: VS-0425-YC213
The Recombinant Anti-DLK1 Vesicular Antibody, EV Displayed (VS-0425-YC213) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to DLK1-expressed cells or tissues. The DLK1 is a transmembrane protein regulating cell growth, influencing the differentiation of various cell types. A single nucleotide variant is associated with obesity, displaying polar overdominance.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line SH-SY5Y
Immunofluorescent staining of human cell line SH-SY5Y shows localization to the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/62262/1219_G12_1_selected.jpg
Normal Tissue
Figure 2 IHC staining of human pituitary gland
Immunohistochemical staining of human pituitary gland shows strong cytoplasmic positivity in anterior lobe.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/ih_additional_tissue/62262/1270_642_200x200.jpg
Normal Tissue
Figure 3 Kidney
Cells in tubules
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5872/167264_A_8_5.jpg
Normal Tissue
Figure 4 Testis
Leydig cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5872/167264_A_6_6.jpg
RNA Expression
Figure 5 RNA cell line category: Group enriched (AF22, Hep G2, SH-SY5Y)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000185559-DLK1
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- DLK1
- Host Animal
- Rat
- Antibody Isotype
- IgG2b
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Delta like non-canonical Notch ligand 1
- Cellular Localization
- Golgi apparatus
- Introduction
- This gene encodes a transmembrane protein that contains multiple epidermal growth factor repeats that functions as a regulator of cell growth. The encoded protein is involved in the differentiation of several cell types including adipocytes. This gene is located in a region of chromosome 14 frequently showing unparental disomy, and is imprinted and expressed from the paternal allele. A single nucleotide variant in this gene is associated with child and adolescent obesity and shows polar overdominance, where heterozygotes carrying an active paternal allele express the phenotype, while mutant homozygotes are normal. [provided by RefSeq, Nov 2015]
- Alternative Names
- Delta1, FA1, pG2, Pref-1, ZOG
- Gene ID
- 8788
- UniProt ID
- P80370
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Datasheet
MSDS
COA
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| HPAB-0790-CN | Human Anti-DLK1 Recombinant Antibody (HPAB-0790-CN) | ELISA, FC, IHC | Chimeric (mouse/human) IgG1, κ |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-282-F(E) | Recombinant Anti-human DLK1 Antibody Fab Fragment | ELISA, FacS, FuncS | Fab |
| MHH-282-F(E) | Recombinant Human Anti-human DLK1 Antibody Fab Fragment | FC, IP, FuncS | Fab |
| HPAB-0789-CN-F(E) | Mouse Anti-DLK1 Recombinant Antibody; Fab Fragment (HPAB-0789-CN-F(E)) | ELISA, FC, IHC | Mouse Fab |
| HPAB-0790-CN-F(E) | Human Anti-DLK1 Recombinant Antibody; Fab Fragment (HPAB-0790-CN-F(E)) | ELISA, FC, IHC | Chimeric (mouse/human) Fab |
| HPAB-0791-CN-F(E) | Human Anti-DLK1 Recombinant Antibody; Fab Fragment (HPAB-0791-CN-F(E)) | ELISA, FC, IHC | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-282-S(P) | Recombinant Anti-human DLK1 Antibody scFv Fragment | ELISA, WB, FuncS | scFv |
| MHH-282-S(P) | Recombinant Human Anti-human DLK1 Antibody scFv Fragment | ELISA, IF, FuncS | scFv |
| HPAB-0789-CN-S(P) | Mouse Anti-DLK1 Recombinant Antibody; scFv Fragment (HPAB-0789-CN-S(P)) | ELISA, FC, IHC | Mouse scFv |
| HPAB-0790-CN-S(P) | Mouse Anti-DLK1 Recombinant Antibody; scFv Fragment (HPAB-0790-CN-S(P)) | ELISA, FC, IHC | Mouse scFv |
| HPAB-0791-CN-S(P) | Human Anti-DLK1 Recombinant Antibody; scFv Fragment (HPAB-0791-CN-S(P)) | ELISA, FC, IHC | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-215CL | Human Anti-DLK1 Recombinant Antibody (TAB-215CL) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-202MZ | Mouse Anti-DLK1 Recombinant Antibody (TAB-202MZ) | FC, FuncS | Mouse IgG2a |
| TAB-203MZ | Mouse Anti-DLK1 Recombinant Antibody (TAB-203MZ) | FC, FuncS | Mouse IgG2a |
| TAB-204MZ | Mouse Anti-DLK1 Recombinant Antibody (TAB-204MZ) | FC, FuncS | Mouse IgG2a |
| TAB-205MZ | Rat Anti-DLK1 Recombinant Antibody (TAB-205MZ) | FC, FuncS | Rat IgG2b |
| TAB-202MZ-S(P) | Mouse Anti-DLK1 Recombinant Antibody; scFv Fragment (TAB-202MZ-S(P)) | FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-210MZ | Anti-Human DLK1 Recombinant Antibody (H06) | WB, IP, ELISA | Human antibody |
| TAB-208MZ-S(P) | Anti-Human DLK1 Recombinant Antibody scFv Fragment (A05) | WB, IP, ELISA | Human antibody |
| TAB-209MZ-S(P) | Anti-Human DLK1 Recombinant Antibody scFv Fragment (A10) | WB, IP, ELISA | Human antibody |
| TAB-210MZ-S(P) | Anti-Human DLK1 Recombinant Antibody scFv Fragment (H06) | WB, IP, ELISA | Human antibody |
| TAB-211MZ-S(P) | Anti-Human DLK1 Recombinant Antibody scFv Fragment (H12) | WB, IP, ELISA | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0999 | Hi-Affi™ Rabbit Anti-DLK1 Recombinant Antibody (clone DS999AB) | WB, ICC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN0565 | PE-A*02:01/Human DLK1 (ILGVLTSLV) MHC Tetramer | FCM, IHC | |
| MHC-CN0566 | APC-A*02:01/Human DLK1 (ILGVLTSLV) MHC Tetramer | FCM, IHC | |
| MHC-CN0567 | FITC-A*02:01/Human DLK1 (ILGVLTSLV) MHC Tetramer | FCM, IHC | |
| MHC-CN0568 | A*02:01/Human DLK1 (ILGVLTSLV) MHC Tetramer | FCM, IHC | |
| MHC-YF395 | A*02:01/Human DLK1 (ILGVLTSLV) MHC Pentamer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY673 | Anti-DLK1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2015 | Anti-Mouse DLK1 Immunohistochemistry Kit | IHC |
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