AbPlus™ Anti-DLK1 Magnetic Beads (B09)

CAT#: VS-0424-XY78

The AbPlus Anti-DLK1 Magnetic Beads (B09) is an innovative affinity resin which is bound with anti-DLK1 specific antibody (B09). The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of DLK1 protein under native and denaturing conditions.

Gene Expression
Figure 1 IF staining of human cell line SH-SY5Y Figure 2 IHC staining of human pituitary gland Figure 3 Kidney Figure 4 Testis Figure 5 RNA cell line category: Group enriched (AF22, Hep G2, SH-SY5Y)

Specifications

  • Applications
  • Immunoprecipitation, Protein Purification
  • Matrix
  • Magrose bead (> 50 μmol/mL gel)
  • Bead Ligand
  • Anti-DLK1 specific antibody (B09)
  • Target
  • DLK1
  • Immunogen
  • DLK1-Fc
  • Target Species
  • Human
  • Antibody Clone
  • B09
  • Bead Capacity
  • 20-30 mg/mL binding antibody
  • Bead size
  • 10-37 μm
  • Stability
  • pH 2-14
  • Format
  • 20% Suspension
  • Buffer
  • PBS, pH 7.4, with 1% BSA
  • Preservative
  • 0.03% Proclin 300
  • Storage
  • Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

Applications

  • Application Notes
  • The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

Target

  • Introduction
  • This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass.
  • Alternative Names
  • DLK1; delta-like 1 homolog (Drosophila); DLK; FA1; ZOG; pG2; DLK-1; PREF1; Delta1; Pref-1; protein delta homolog 1; secredeltin; fetal antigen 1; preadipocyte factor 1
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