Recombinant Anti-F2R Vesicular Antibody, EV Displayed (VS-0425-YC593)

CAT#: VS-0425-YC593

The Recombinant Anti-F2R Vesicular Antibody, EV Displayed (VS-0425-YC593) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to F2R-expressed cells or tissues. F2R is a coagulation factor II receptor, a G-protein coupled receptor activated through proteolytic cleavage. It regulates thrombotic response.

Gene Expression
Figure 1 Colon Figure 2 Kidney Figure 3 Testis Figure 4 Lymph node Figure 5 RNA cell line category: Cell line enhanced (hTERT-RPE1, HUVEC TERT2, WM-115)

Recombinant Antibody

  • Application
  • ELISA, FC, Stim, Cell-uptake
  • Product Type
  • Ab-Fc-EVs
  • Antibody Quantification (Ab/EV)
  • ~100 Ab/EV
  • Target
  • F2R
  • Host Animal
  • Mouse
  • Antibody Isotype
  • IgG
  • Species Reactivity
  • Human
  • Expression Cell
  • Mammalian cell

Engineered EVs

  • EV-sorting domain
  • CD63
  • Fc-binding domain
  • Protein A
  • EV Size
  • 30~150 nm
  • Producing Cell
  • HEK293F
  • Isolation Method
  • Gradient centrifugation
  • Purification
  • qEV size exclusion chromatography
  • Concentration
  • 1 x 10¹⁰
  • Size
  • 1 mL
  • Buffer
  • PBS
  • Storage
  • Store at -80°C for 12 months

Target

  • Full Name
  • Coagulation factor II thrombin receptor
  • Biological Process
  • Blood coagulation, Hemostasis
  • Molecular Function
  • G-protein coupled receptor, Receptor, Transducer
  • Introduction
  • Coagulation factor II receptor is a 7-transmembrane receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. F2R is a G-protein coupled receptor family member. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]
  • Alternative Names
  • CF2R, PAR-1, PAR1, TR
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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