Recombinant Anti-F2R Vesicular Antibody, EV Displayed (VS-0425-YC593) (CAT#: VS-0425-YC593)
The Recombinant Anti-F2R Vesicular Antibody, EV Displayed (VS-0425-YC593) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to F2R-expressed cells or tissues. F2R is a coagulation factor II receptor, a G-protein coupled receptor activated through proteolytic cleavage. It regulates thrombotic response.

(Peripheral nerve/ganglion
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12962/34660_A_8_3.jpg

(Cells in glomeruli
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12962/34660_A_9_5.jpg

(Cells in seminiferous ducts
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12962/34660_A_4_6.jpg

(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12962/34660_A_9_8.jpg

(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000181104-F2R
Recombinant Antibody
- Application
- ELISA, FC, Stim, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- F2R
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Coagulation factor II thrombin receptor
- Biological Process
- Blood coagulation, Hemostasis
- Molecular Function
- G-protein coupled receptor, Receptor, Transducer
- Introduction
- Coagulation factor II receptor is a 7-transmembrane receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. F2R is a G-protein coupled receptor family member. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]
- Alternative Names
- CF2R, PAR-1, PAR1, TR
- Gene ID
- 2149
- UniProt ID
- P25116
Downloads
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See other products for "F2R"
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-345 | Recombinant Anti-human F2R Antibody | ELISA, WB, Neut, FuncS | IgG |
MHH-345 | Recombinant Human Anti-human F2R Antibody | WB, FC, FuncS | IgG |
HPAB-0272-YC | Mouse Anti-F2R Recombinant Antibody (clone 4E7.J14.L16) | ELISA, Stim | Mouse IgG |
VS7-HM921 | Mouse Anti-F2R Recombinant Antibody (clone 5E2E6) | IHC | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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