Recombinant Anti-F2R Vesicular Antibody, EV Displayed (VS-0425-YC593) (CAT#: VS-0425-YC593)
The Recombinant Anti-F2R Vesicular Antibody, EV Displayed (VS-0425-YC593) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to F2R-expressed cells or tissues. F2R is a coagulation factor II receptor, a G-protein coupled receptor activated through proteolytic cleavage. It regulates thrombotic response.
Specific Inquiry
Normal Tissue
RNA Expression

Figure 1 Colon
(Peripheral nerve/ganglion
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12962/34660_A_8_3.jpg
(Peripheral nerve/ganglion
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12962/34660_A_8_3.jpg

Figure 2 Kidney
(Cells in glomeruli
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12962/34660_A_9_5.jpg
(Cells in glomeruli
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12962/34660_A_9_5.jpg

Figure 3 Testis
(Cells in seminiferous ducts
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12962/34660_A_4_6.jpg
(Cells in seminiferous ducts
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12962/34660_A_4_6.jpg

Figure 4 Lymph node
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12962/34660_A_9_8.jpg
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12962/34660_A_9_8.jpg

Figure 5 RNA cell line category: Cell line enhanced (hTERT-RPE1, HUVEC TERT2, WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000181104-F2R
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000181104-F2R
Recombinant Antibody
- Application
- ELISA, FC, Stim, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- F2R
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Coagulation factor II thrombin receptor
- Biological Process
- Blood coagulation, Hemostasis
- Molecular Function
- G-protein coupled receptor, Receptor, Transducer
- Introduction
- Coagulation factor II receptor is a 7-transmembrane receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. F2R is a G-protein coupled receptor family member. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]
- Alternative Names
- CF2R, PAR-1, PAR1, TR
- Gene ID
- 2149
- UniProt ID
- P25116
Downloads
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MOB-345 | Recombinant Anti-human F2R Antibody | ELISA, WB, Neut, FuncS | IgG |
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HPAB-0272-YC | Mouse Anti-F2R Recombinant Antibody (clone 4E7.J14.L16) | ELISA, Stim | Mouse IgG |
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For Research Use Only. Not For Clinical Use.
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