Mouse Anti-F2R Recombinant Antibody (clone 4E7.J14.L16); scFv Fragment (CAT#: HPAB-0272-YC-S(P))
The protease-activated receptor 1 (PAR1) is a thrombin receptor which belongs to the class of G protein-coupled receptors (GCPR). PAR1 is expressed in various tissues, such as endothelial cells, smooth muscles cells, fibroblasts, neurons and human platelets. It is involved in cellular responses associated with hemostasis, proliferation, and tissue injury.
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Normal Tissue
RNA Expression
Figure 1 Colon
(Peripheral nerve/ganglion
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12962/34660_A_8_3.jpg
(Peripheral nerve/ganglion
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12962/34660_A_8_3.jpg
Figure 2 Kidney
(Cells in glomeruli
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12962/34660_A_9_5.jpg
(Cells in glomeruli
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12962/34660_A_9_5.jpg
Figure 3 Testis
(Cells in seminiferous ducts
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12962/34660_A_4_6.jpg
(Cells in seminiferous ducts
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12962/34660_A_4_6.jpg
Figure 4 Lymph node
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12962/34660_A_9_8.jpg
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12962/34660_A_9_8.jpg
Figure 5 RNA cell line category: Cell line enhanced (hTERT-RPE1, HUVEC TERT2, WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000181104-F2R
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000181104-F2R
Specifications
- Immunogen
- Human PAR1 (AA #27-102)/thioredoxin fusion protein
- Host Species
- Mouse
- Type
- Mouse scFv
- Specificity
- Human F2R
- Species Reactivity
- Human
- Clone
- 4E7.J14.L16
- Applications
- ELISA, Stim
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- F2R; coagulation factor II (thrombin) receptor; TR; HTR; CF2R; PAR1; PAR-1; proteinase-activated receptor 1; protease-activated receptor 1
- Gene ID
- 2149
- UniProt ID
- A0A024RAP7
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-345 | Recombinant Anti-human F2R Antibody | ELISA, WB, Neut, FuncS | IgG |
| MHH-345 | Recombinant Human Anti-human F2R Antibody | WB, FC, FuncS | IgG |
| HPAB-0272-YC | Mouse Anti-F2R Recombinant Antibody (clone 4E7.J14.L16) | ELISA, Stim | Mouse IgG |
| VS7-HM921 | Mouse Anti-F2R Recombinant Antibody (clone 5E2E6) | IHC | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
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