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    F2R

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    For Research Use Only. Not For Clinical Use.


    Coagulation factor II receptor is a 7-transmembrane receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. F2R is a G-protein coupled receptor family member. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]
    Protein class

    FDA approved drug targets, G-protein coupled receptors

    Predicted location

    Intracellular, Membrane (different isoforms)

    Single cell type specificity

    Cell type enriched (Hepatic stellate cells)

    Immune cell specificity

    Immune cell enhanced (gdT-cell)

    Cell line specificity

    Cell line enhanced (hTERT-RPE1, HUVEC TERT2, WM-115)

    Molecular function

    G-protein coupled receptor, Receptor, Transducer

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