Recombinant Anti-FLT4 Vesicular Antibody, EV Displayed (VS-0425-YC359) (CAT#: VS-0425-YC359)

The Recombinant Anti-FLT4 Vesicular Antibody, EV Displayed (VS-0425-YC359) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to FLT4-expressed cells or tissues. The FLT4 is a receptor tyrosine kinase for VEGFs, which is critical for lymphatic endothelium maintenance, with mutations causing lymphedema.

Specific Inquiry
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Normal Tissue
RNA Expression

Recombinant Antibody

  • Application
  • ELISA, FC, Cell-uptake
  • Product Type
  • Ab-Fc-EVs
  • Antibody Quantification (Ab/EV)
  • ~100 Ab/EV
  • Target
  • FLT4
  • Host Animal
  • Mouse
  • Antibody Isotype
  • IgG1
  • Species Reactivity
  • Human
  • Expression Cell
  • Mammalian cell

Engineered EVs

  • EV-sorting domain
  • CD63
  • Fc-binding domain
  • Protein G
  • EV Size
  • 30~150 nm
  • Producing Cell
  • HEK293F
  • Isolation Method
  • Gradient centrifugation
  • Purification
  • qEV size exclusion chromatography
  • Concentration
  • 1 x 10¹⁰
  • Size
  • 1 mL
  • Buffer
  • PBS
  • Storage
  • Store at -80°C for 12 months

Target

  • Full Name
  • Fms related receptor tyrosine kinase 4
  • Biological Process
  • Angiogenesis
  • Molecular Function
  • Kinase, Receptor, Transferase, Tyrosine-protein kinase
  • Cellular Localization
  • Microtubules, Primary cilium, Cytokinetic bridge, Calyx, Connecting piece, Mid piece, Principal piece
  • Introduction
  • This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA.
  • Alternative Names
  • PCL, VEGFR-3, VEGFR3

Downloads

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