Recombinant Anti-FLT4 Vesicular Antibody, EV Displayed (VS-0425-YC359)
CAT#: VS-0425-YC359
The Recombinant Anti-FLT4 Vesicular Antibody, EV Displayed (VS-0425-YC359) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to FLT4-expressed cells or tissues. The FLT4 is a receptor tyrosine kinase for VEGFs, which is critical for lymphatic endothelium maintenance, with mutations causing lymphedema.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HEK 293
Immunofluorescent staining of human cell line HEK 293 shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/46519/1909_G1_4_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nuclear speckles & plasma membrane.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/99/if_selected.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/67906/153589_A_9_3.jpg
Normal Tissue
Figure 4 Kidney
Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/67906/153589_A_7_5.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (AN3-CA, BEWO, HEK93, HL-60, HUVEC TERT2, JURKAT, T-47d, TIME)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000037280-FLT4
❮
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- FLT4
- Host Animal
- Mouse
- Antibody Isotype
- IgG1
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein G
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Fms related receptor tyrosine kinase 4
- Biological Process
- Angiogenesis
- Molecular Function
- Kinase, Receptor, Transferase, Tyrosine-protein kinase
- Cellular Localization
- Microtubules, Primary cilium, Cytokinetic bridge, Calyx, Connecting piece, Mid piece, Principal piece
- Introduction
- This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA.
- Alternative Names
- PCL, VEGFR-3, VEGFR3
- Gene ID
- 2324
- UniProt ID
- P35916
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "FLT4"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1490z | Mouse Anti-FLT4 Recombinant Antibody (clone 26D3) | WB, FC, IHC, IP | Mouse IgG2a, κ |
| VS3-QX433 | Mouse Anti-FLT4 Recombinant Antibody (clone 818CT12.1.1) | WB, IHC, FC | Mouse IgG2a |
| VS3-CJ913 | Mouse Anti-FLT4 Recombinant Antibody (VS3-CJ913) | IHC | Mouse IgG |
| VS3-WK1954 | Recombinant Rabbit Anti-Mouse FLT4 Capture Antibody (clone R94-7S-4) | ELISA | Rabbit IgG |
| VS3-WK1955 | Recombinant Rabbit Anti-Mouse FLT4 Detection Antibody (clone R35-6N-6) | ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-292CL | Human Anti-FLT4 Recombinant Antibody (TAB-292CL) | ELISA | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-015CQ | Anti-Human FLT4 Recombinant Antibody (9D9F9) | ELISA, FC | |
| TAB-015CQ-S(P) | Anti-Human FLT4 Recombinant Antibody scFv Fragment (9D9F9) | ELISA, FC | |
| TAB-015CQ-F(E) | Anti-Human FLT4 Recombinant Antibody Fab Fragment (9D9F9) | ELISA, FC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-850CQ | Rat Anti-Flt4 Recombinant Antibody (clone AFL4) | IHC, Block, ELISA, IP, WB | Rat IgG2a, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-851CQ | Mouse Anti-Flt4 Recombinant Antibody (clone CBL842) | Neut | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4181 | Hi-Affi™ Rabbit Anti-Flt4 Recombinant Antibody (clone SI258DS) | ELISA | Rabbit IgG |
| MOR-4182 | Hi-Affi™ Rabbit Anti-FLT4 Recombinant Antibody (clone SI259DS) | ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY54 | Human Anti-FLT4 scFv-Fc Chimera (VS-0425-FY54) | ELISA | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2585 | Anti-FLT4 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2586 | Anti-Mouse FLT4 Immunohistochemistry Kit | IHC |
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