Recombinant Anti-GUCY2C Vesicular Antibody, EV Displayed (VS-0425-YC498) (CAT#: VS-0425-YC498)

• Application
• ELISA, FC, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• GUCY2C

• Host Animal
• Rabbit

• Antibody Isotype
• IgG

• Species Reactivity
• Human

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• Protein A

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• Guanylate cyclase 2C

• Biological Process
• cGMP biosynthesis

• Molecular Function
• Lyase, Receptor

• Cellular Localization
• Vesicles

• Introduction
• This gene encodes a transmembrane protein that functions as a receptor for endogenous peptides guanylin and uroguanylin, and the heat-stable E. coli enterotoxin. The encoded protein activates the cystic fibrosis transmembrane conductance regulator. Mutations in this gene are associated with familial diarrhea (autosomal dominant) and meconium ileus (autosomal recessive). [provided by RefSeq, Nov 2016]

• Alternative Names
• GUC2C, STAR

• Gene ID
• 2984

• UniProt ID
• P25092

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