


Anti-GUCY2C Recombinant Antibody Products

Anti-GUCY2C Products
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- Species Reactivity: Human, Mouse
- Type: Mouse Fab
- Application: ELISA, FC, WB
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human, Mouse
- Type: Chimeric (mouse/human) Fab
- Application: ELISA, FC, WB
- Rabbit Anti-GUCY2C Recombinant Antibody (HPAB-AP097-YC) (HPAB-AP097-YC)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA, IHC
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG1, κ
- Application: ELISA, FC, IF
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human, Mouse
- Type: Chimeric (mouse/human) IgG
- Application: ELISA, FC, WB
- Rabbit Anti-GUCY2C Recombinant Antibody (HPAB-AP098-YC) (HPAB-AP098-YC)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA, IHC
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- Species Reactivity: Human
- Type: Mouse IgG2b, κ
- Application: WB, IP, ELISA
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- Species Reactivity: Human
- Type: Mouse IgG2b, κ
- Application: ELISA, WB
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- Derivation: Human
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, FC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FC
- Human Anti-GUCY2C Recombinant Antibody (VS-0723-WK151) (VS-0723-WK151)
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- Derivation: Chimeric (rabbit/human)
- Species Reactivity: Human
- Type: Chimeric (rabbit/human) IgG1
- Application: FC
- Recombinant Anti-Human GUCY2C Antibody Fab Fragment (MOB-2397z-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: Neut, IF, FuncS
- Recombinant Anti-Human GUCY2C Antibody scFv Fragment (MOB-2397z-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: IF, FC, Biosensors, FuncS
- Recombinant Mouse Anti-GUCY2C Soluble TCR (CH6) (C-Cys) (VS-0622-YF3866)
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- Species Reactivity: Mus musculus
- Epitope: YKETLTRILPPARKL
- Recombinant Mouse Anti-GUCY2C Soluble TCR (CH6) (KIH) (VS-0622-YF6574)
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- Species Reactivity: Mus musculus
- Epitope: YKETLTRILPPARKL
- Rabbit Anti-GUCY2C Recombinant Antibody; scFv Fragment (HPAB-AP097-YC-S(P)) (HPAB-AP097-YC-S(P))
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- Species Reactivity: Human
- Type: Rabbit scFv
- Application: ELISA, IHC
- Rabbit Anti-GUCY2C Recombinant Antibody; scFv Fragment (HPAB-AP098-YC-S(P)) (HPAB-AP098-YC-S(P))
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- Species Reactivity: Human
- Type: Rabbit scFv
- Application: ELISA, IHC
- Rabbit Anti-GUCY2C Recombinant Antibody; Fab Fragment (HPAB-AP097-YC-F(E)) (HPAB-AP097-YC-F(E))
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- Species Reactivity: Human
- Type: Rabbit Fab
- Application: ELISA, IHC
- Rabbit Anti-GUCY2C Recombinant Antibody; Fab Fragment (HPAB-AP098-YC-F(E)) (HPAB-AP098-YC-F(E))
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- Species Reactivity: Human
- Type: Rabbit Fab
- Application: ELISA, IHC
- Mouse Anti-GUCY2C Recombinant Soluble TCR (CH6) (scTCR-405ZP-S(P))
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- Species Reactivity: Mus musculus
- Epitope: YKETLTRILPPARKL
- Recombinant Mouse Anti-GUCY2C Soluble TCR (CH6) (ZIP-Fos/ZIP-Jun) (VS-0622-YF1158)
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- Species Reactivity: Mus musculus
- Epitope: YKETLTRILPPARKL
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- Species Reactivity: Human, Mouse
- Type: Mouse scFv
- Application: ELISA, FC, WB
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- Species Reactivity: Human, Mouse
- Type: Mouse scFv
- Application: ELISA, FC, WB
- Anti-Guanylyl cyclase C (clone 5F9)-vc-MMAE ADC (ADC-049LZY)
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- Target: Guanylyl cyclase C
- Linker: VC (valine-citrulline)
- Drug: MMAE (monomethyl auristatin E)
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- Target: GCC
- Linker: mc-val-cit-PABC (cleavable maleimidocaproyl-valyl-citrullinyl-p-aminobenzyloxycarbonyl )
- Drug: MMAE (Monomethyl auristatin E)
- Chicken Anti-GUCY2C Polyclonal IgY (BRD-0245MZ)
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- Species Reactivity: Human
- Type: Chicken antibody
- Application: WB
- Anti-GCC (clone 5F9)-vc-MMAE ADC (ADC-260CL)
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- Target: GCC
- Linker: VC (valine-citrulline)
- Drug: MMAE (Monomethyl auristatin E)
- Anti-GCC (clone 5F9)-mc-MMAF ADC (ADC-262CL)
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- Target: GCC
- Linker: Mc (maleimidocaproyl)
- Drug: MMAF (Monomethyl auristatin F)
- Anti-GCC (5F9)-Cleavable peptide linker-MMAE ADC (ADC-121LCT)
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- Target: Guanylyl cyclase C (GCC or GUCY2C)
- Linker: Cleavable peptide linker
- Drug: MMAE (Monomethyl auristatin E)
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- Species Reactivity: Human
- Target: GUCY2C
- Host Animal: Rabbit
- Application: ELISA, FC, Cell-uptake
- Human Anti-GUCY2C scFv-Fc Chimera (VS-0425-FY115) (VS-0425-FY115)
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- Species Reactivity: Human, Mouse
- Type: Human IgG1, scFv-Fc
- Application: WB, ELISA, FC
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For Research Use Only. Not For Clinical Use.
Creative Biolabs offers a range of anti-GUCY2C recombinant antibodies that are engineered for a wide range of immunology applications. Our strict quality control system ensures the accuracy and specificity of these antibodies in various immunology applications, making them an important tool in diverse GUCY2C targeting studies.
GUCY2C: A Promising Therapeutic Target for Cancer
GUCY2C, activated by various factors, regulates intestinal functions and cell proliferation. While primarily linked to intestinal disorders like irritable bowel syndrome, inflammatory bowel diseases, and gastrointestinal cancers, it's also implicated in neurological conditions. Notably, GUCY2C is overexpressed in most colorectal cancers, making it a prospective therapeutic target. CAR-T cell therapies and antibody treatments targeting GUCY2C have demonstrated efficacy and safety in eliminating colorectal cancer cells, highlighting the potential of GUCY2C-based therapies.
Alternative Names
Guanylate cyclase 2C; Guanylyl cyclase C; GCC; GC-C; Sta receptor; StaR; STAR; DIAR6; GUC2C; MECIL; MUCIL; intestinal guanylate cyclase; guanylate cyclase-C receptor; heat-stable enterotoxin receptor; hSTAR.
Background
Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Transporters
Membrane
Cell type enhanced (Enteroendocrine cells, Paneth cells, Proximal enterocytes, Intestinal goblet cells, Undifferentiated cells, Distal enterocytes)
Immune cell enhanced (memory B-cell)
Cell line enhanced (AN3-CA, CACO-2, CAPAN-2, SiHa)
Homotrimer (PubMed:11123935). Interacts via its C-terminal region with PDZK2 (PubMed:11950846). Interacts with the lectin chaperone VIP36 (PubMed:23269669).
Lyase, Receptor
Anti-GUCY2C Recombinant Antibody Products
Creative Biolabs offers an extensive selection of recombinant antibodies that specifically target GUCY2C, optimized for consistent identification and neutralization. Available in various formats, these antibodies demonstrate exceptional specificity and affinity, making them ideal for a diverse array of applications. Whether utilized for research purposes or therapeutic advancements, Creative Biolabs’ anti-GUCY2C antibodies serve as essential tools in advancing our understanding of immunology, cancer, and related fields.
Table 1. Featured anti-GUCY2C recombinant antibody products at Creative Biolabs.
Cat. No. | Product Name | Target Species | Host Species | Applications |
HPAB-AP097-YC | Rabbit Anti-GUCY2C Recombinant Antibody (HPAB-AP097-YC) | Human | Rabbit IgG | ELISA, IHC |
TAB-062CQ | Human Anti-GUCY2C Recombinant Antibody (TAB-062CQ) | Human, Mouse | Chimeric (mouse/human) IgG | ELISA, WB, FC, etc. |
TAB-061CQ | Mouse Anti-GUCY2C Recombinant Antibody (TAB-061CQ) | Human, Mouse | Mouse IgG1, κ | ELISA, FC, IF |
HPAB-AP098-YC | Rabbit Anti-GUCY2C Recombinant Antibody (HPAB-AP098-YC) | Human | Rabbit IgG | ELISA, IHC |
MOB-069CQ | Mouse Anti-GUCY2C Recombinant Antibody (clone YC099) | Human | Mouse IgG2b, κ | WB, IP, ELISA |
Creative Quality Control
Creative Biolabs is a leader in the development of premium anti-GUCY2C recombinant antibodies tailored for research applications. We pride ourselves on our state-of-the-art facilities and rigorous quality control measures, guaranteeing that our products exhibit outstanding specificity and strong binding affinity. Our skilled team of biotechnology experts is committed to advancing our techniques and delivering dependable solutions to empower your scientific research and initiatives.
Fig.1 ELISA analysis of anti-GUCY2C antibody
(Cat# TAB-061CQ, Creative Biolabs).
Fig.2 WB analysis of anti-GUCY2C antibody
(Cat# TAB-061CQ, Creative Biolabs).
Fig.3 DB analysis of anti-GUCY2C antibody
(Cat# TAB-061CQ, Creative Biolabs).
Customer Reviews

Mouse Anti-GUCY2C Recombinant Antibody (TAB-061CQ) (TAB-061CQ)

Human Anti-GUCY2C Recombinant Antibody (TAB-062CQ) (TAB-062CQ)

Rabbit Anti-GUCY2C Recombinant Antibody (HPAB-AP097-YC) (HPAB-AP097-YC)
Anti-GUCY2C Recombinant Antibody Production
Creative Biolabs utilizes advanced recombinant antibody production techniques specifically designed for the creation of anti-GUCY2C antibodies. Our state-of-the-art genetic engineering methodologies allow for the versatile generation of premium antibodies, guaranteeing a steady and dependable supply to meet your diverse research needs.
Featured Anti-GUCY2C Recombinant Antibody Production Platform
Fig.4 Milligram-scale anti-GUCY2C recombinant antibody production.
Fig.5 Gram-scale anti-GUCY2C recombinant antibody production.
Anti-GUCY2C Recombinant Antibody Modalities
Creative Biolabs offers an extensive range of premium anti-GUCY2C recombinant antibodies, tailored to meet the diverse needs of researchers around the globe.
Fig.6 Full-length anti-GUCY2C recombinant antibody production and modalities.
GUCY2C-Targeted Drug Information
Public Drug Information Targeting GUCY2C
Table 2. Public drug targeting GUCY2C.
Company | Research Phase | Classification | Condition |
Legend Biotech (Originator) | Phase I |
Cancer Immunotherapy Chimeric Antigen Receptor-Modified T Cells (CAR T Cells) (Second-Generation CAR) |
Cancer, gastrointestinal |
Parasol Biotech (Originator) | Phase I |
Cancer Immunotherapy Chimeric Antigen Receptor-Modified T Cells (CAR T Cells) |
Cancer, colorectal |
Innovative Cellular Therapeutics (ICT) (Originator) | Phase I |
Cancer Immunotherapy Chimeric Antigen Receptor-Modified T Cells (CAR T Cells) |
Cancer, colorectal Cancer, colorectal, metastatic Digestive-gastrointestinal cancer |
Thomas Jefferson University (Originator) Viral Gene |
Phase I |
Cancer Immunotherapy Cancer Vaccines Recombinant Vector Vaccines |
Cancer, colon |
Thomas Jefferson University (Originator) | Preclinical |
Cancer Immunotherapy Chimeric Antigen Receptor-Modified T Cells (CAR T Cells) |
Digestive-gastrointestinal cancer |
Triumvira (Originator) | Preclinical |
Adoptive Cell Therapy Cancer Immunotherapy |
Cancer, stomach |
Legend Biotech (Originator) | Biological Testing |
Cancer Immunotherapy Chimeric Antigen Receptor-Modified T Cells (CAR T Cells) (Second-Generation CAR) |
Cancer, colorectal |
Shenzhen Fapon Biotech (Originator) | Biological Testing |
Cancer Immunotherapy Humanized Monoclonal Antibodies |
Cancer, colon |
Zhejiang Xuxu Technology (Originator) | Biological Testing |
Cancer Immunotherapy Chimeric Antigen Receptor-Modified T Cells (CAR T Cells) (Second-Generation CAR) |
Cancer |
Shenzhen First Condor Life Science (Originator) | Biological Testing |
Cancer Immunotherapy Murine Monoclonal Antibodies |
Cancer |
(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)
Contact us to discuss your specific needs to find out how our anti-GUCY2C antibodies will help your research efforts.