+ Filter
Loading...
Custom Services order now ship next day

Anti-GUCY2C Recombinant Antibody Products

Loading...

Anti-GUCY2C Products

More Infomation

Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag

More Infomation

Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us

For Research Use Only. Not For Clinical Use.


Creative Biolabs offers a range of anti-GUCY2C recombinant antibodies that are engineered for a wide range of immunology applications. Our strict quality control system ensures the accuracy and specificity of these antibodies in various immunology applications, making them an important tool in diverse GUCY2C targeting studies.

GUCY2C: A Promising Therapeutic Target for Cancer

GUCY2C, activated by various factors, regulates intestinal functions and cell proliferation. While primarily linked to intestinal disorders like irritable bowel syndrome, inflammatory bowel diseases, and gastrointestinal cancers, it's also implicated in neurological conditions. Notably, GUCY2C is overexpressed in most colorectal cancers, making it a prospective therapeutic target. CAR-T cell therapies and antibody treatments targeting GUCY2C have demonstrated efficacy and safety in eliminating colorectal cancer cells, highlighting the potential of GUCY2C-based therapies.

Alternative Names

Guanylate cyclase 2C; Guanylyl cyclase C; GCC; GC-C; Sta receptor; StaR; STAR; DIAR6; GUC2C; MECIL; MUCIL; intestinal guanylate cyclase; guanylate cyclase-C receptor; heat-stable enterotoxin receptor; hSTAR.

Background

This gene encodes a transmembrane protein that functions as a receptor for endogenous peptides guanylin and uroguanylin, and the heat-stable E. coli enterotoxin. The encoded protein activates the cystic fibrosis transmembrane conductance regulator. Mutations in this gene are associated with familial diarrhea (autosomal dominant) and meconium ileus (autosomal recessive).
Protein class

Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Transporters

Predicted location

Membrane

Single cell type specificity

Cell type enhanced (Enteroendocrine cells, Paneth cells, Proximal enterocytes, Intestinal goblet cells, Undifferentiated cells, Distal enterocytes)

Immune cell specificity

Immune cell enhanced (memory B-cell)

Cell line specificity

Cell line enhanced (AN3-CA, CACO-2, CAPAN-2, SiHa)

Interaction

Homotrimer (PubMed:11123935). Interacts via its C-terminal region with PDZK2 (PubMed:11950846). Interacts with the lectin chaperone VIP36 (PubMed:23269669).

Molecular function

Lyase, Receptor

More Types Infomation

Anti-GUCY2C Recombinant Antibody Products

Creative Biolabs offers an extensive selection of recombinant antibodies that specifically target GUCY2C, optimized for consistent identification and neutralization. Available in various formats, these antibodies demonstrate exceptional specificity and affinity, making them ideal for a diverse array of applications. Whether utilized for research purposes or therapeutic advancements, Creative Biolabs’ anti-GUCY2C antibodies serve as essential tools in advancing our understanding of immunology, cancer, and related fields.

Table 1. Featured anti-GUCY2C recombinant antibody products at Creative Biolabs.

Cat. No. Product Name Target Species Host Species Applications
HPAB-AP097-YC Rabbit Anti-GUCY2C Recombinant Antibody (HPAB-AP097-YC) Human Rabbit IgG ELISA, IHC
TAB-062CQ Human Anti-GUCY2C Recombinant Antibody (TAB-062CQ) Human, Mouse Chimeric (mouse/human) IgG ELISA, WB, FC, etc.
TAB-061CQ Mouse Anti-GUCY2C Recombinant Antibody (TAB-061CQ) Human, Mouse Mouse IgG1, κ ELISA, FC, IF
HPAB-AP098-YC Rabbit Anti-GUCY2C Recombinant Antibody (HPAB-AP098-YC) Human Rabbit IgG ELISA, IHC
MOB-069CQ Mouse Anti-GUCY2C Recombinant Antibody (clone YC099) Human Mouse IgG2b, κ WB, IP, ELISA

Creative Quality Control

Creative Biolabs is a leader in the development of premium anti-GUCY2C recombinant antibodies tailored for research applications. We pride ourselves on our state-of-the-art facilities and rigorous quality control measures, guaranteeing that our products exhibit outstanding specificity and strong binding affinity. Our skilled team of biotechnology experts is committed to advancing our techniques and delivering dependable solutions to empower your scientific research and initiatives.

Fig.1 ELISA analysis. (Creative Biolabs Original)Fig.1 ELISA analysis of anti-GUCY2C antibody
(Cat# TAB-061CQ, Creative Biolabs).

Fig.2 WB analysis. (Creative Biolabs Original)Fig.2 WB analysis of anti-GUCY2C antibody
(Cat# TAB-061CQ, Creative Biolabs).

Fig.3 DB analysis. (Creative Biolabs Original)Fig.3 DB analysis of anti-GUCY2C antibody
(Cat# TAB-061CQ, Creative Biolabs).

Customer Reviews

Excellent
Pi***h
Mouse Anti-GUCY2C Recombinant Antibody (TAB-061CQ) (TAB-061CQ)
Creative Biolabs’ anti-GUCY2C recombinant antibodies have significantly advanced my research endeavors. The remarkable specificity and sensitivity of these antibodies have enabled us to obtain accurate and consistent results across various experiments. In addition, the outstanding technical assistance from their team has played a crucial role in facilitating uninterrupted workflow and driving our projects forward.
16/Nov/2023
Excellent
Ag***i
Human Anti-GUCY2C Recombinant Antibody (TAB-062CQ) (TAB-062CQ)
Creative Biolabs' anti-GUCY2C antibodies have continually satisfied me in terms of quality and efficacy. The consistency of the data achieved with these antibodies is outstanding, making them a dependable tool in our work. The rapid delivery and competitive pricing further enhance the value of their products.
5/Dec/2023
Excellent
Za***a
Rabbit Anti-GUCY2C Recombinant Antibody (HPAB-AP097-YC) (HPAB-AP097-YC)
As a researcher working on complex biological systems, I appreciate the versatility of Creative Biolabs' anti-GUCY2C antibodies. These antibodies have proven to be highly effective in various applications, including IHC and ELISA. The flexibility and customization options offered by Creative Biolabs have allowed us to tailor our experiments to specific research needs.
22/Oct/2024

Anti-GUCY2C Recombinant Antibody Production

Creative Biolabs utilizes advanced recombinant antibody production techniques specifically designed for the creation of anti-GUCY2C antibodies. Our state-of-the-art genetic engineering methodologies allow for the versatile generation of premium antibodies, guaranteeing a steady and dependable supply to meet your diverse research needs.

Featured Anti-GUCY2C Recombinant Antibody Production Platform Fig.4 Milligram-scale. (Creative Biolabs Original)
Fig.4 Milligram-scale anti-GUCY2C recombinant antibody production.

Fig.5 Gram-scale. (Creative Biolabs Original)Fig.5 Gram-scale anti-GUCY2C recombinant antibody production.

Anti-GUCY2C Recombinant Antibody Modalities

Creative Biolabs offers an extensive range of premium anti-GUCY2C recombinant antibodies, tailored to meet the diverse needs of researchers around the globe.

Fig.6 GUCY2C antibody production and modalities. (Creative Biolabs Original)Fig.6 Full-length anti-GUCY2C recombinant antibody production and modalities.

GUCY2C-Targeted Drug Information

Public Drug Information Targeting GUCY2C

Table 2. Public drug targeting GUCY2C.

Company Research Phase Classification Condition
Legend Biotech (Originator) Phase I Cancer Immunotherapy
Chimeric Antigen Receptor-Modified T Cells (CAR T Cells) (Second-Generation CAR)
Cancer, gastrointestinal
Parasol Biotech (Originator) Phase I Cancer Immunotherapy
Chimeric Antigen Receptor-Modified T Cells (CAR T Cells)
Cancer, colorectal
Innovative Cellular Therapeutics (ICT) (Originator) Phase I Cancer Immunotherapy
Chimeric Antigen Receptor-Modified T Cells (CAR T Cells)
Cancer, colorectal
Cancer, colorectal, metastatic
Digestive-gastrointestinal cancer
Thomas Jefferson University (Originator)
Viral Gene
Phase I Cancer Immunotherapy
Cancer Vaccines
Recombinant Vector Vaccines
Cancer, colon
Thomas Jefferson University (Originator) Preclinical Cancer Immunotherapy
Chimeric Antigen Receptor-Modified T Cells (CAR T Cells)
Digestive-gastrointestinal cancer
Triumvira (Originator) Preclinical Adoptive Cell Therapy
Cancer Immunotherapy
Cancer, stomach
Legend Biotech (Originator) Biological Testing Cancer Immunotherapy
Chimeric Antigen Receptor-Modified T Cells (CAR T Cells) (Second-Generation CAR)
Cancer, colorectal
Shenzhen Fapon Biotech (Originator) Biological Testing Cancer Immunotherapy
Humanized Monoclonal Antibodies
Cancer, colon
Zhejiang Xuxu Technology (Originator) Biological Testing Cancer Immunotherapy
Chimeric Antigen Receptor-Modified T Cells (CAR T Cells) (Second-Generation CAR)
Cancer
Shenzhen First Condor Life Science (Originator) Biological Testing Cancer Immunotherapy
Murine Monoclonal Antibodies
Cancer

(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)

Contact us to discuss your specific needs to find out how our anti-GUCY2C antibodies will help your research efforts.

Go to compare

Go to compare