Recombinant Anti-IL10RA Vesicular Antibody, EV Displayed (VS-0425-YC589)
CAT#: VS-0425-YC589
The Recombinant Anti-IL10RA Vesicular Antibody, EV Displayed (VS-0425-YC589) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to IL10RA-expressed cells or tissues. IL10RA is a receptor for interleukin 10, inhibiting proinflammatory cytokine synthesis. It promotes myeloid cell survival through the PI 3-kinase/AKT pathway, with activation leading to kinase phosphorylation. Two transcript variants exist for this gene.



Recombinant Antibody
- Application
- Block, ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- IL10RA
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human, Chimpanzee, Cynomolgus
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Interleukin 10 receptor subunit alpha
- Molecular Function
- Receptor
- Cellular Localization
- Plasma membrane, Cytosol, Primary cilium
- Introduction
- The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.
- Alternative Names
- CD210, CD210a, CDW210A, HIL-10R, IL10R
- Gene ID
- 3587
- UniProt ID
- Q13651
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Datasheet
MSDS
COA
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See other products for "IL10RA"
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MOB-550 | Recombinant Anti-human IL10RA Antibody | WB, ELISA, IHC, FuncS | IgG |
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HPAB-0277-CN | Human Anti-IL10RA Recombinant Antibody (HPAB-0277-CN) | ELISA, FC, Block, Neut | Human IgG2 |
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CAT | Product Name | Application | Type |
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MOB-550-F(E) | Recombinant Anti-human IL10RA Antibody Fab Fragment | ELISA, RIA, FuncS | Fab |
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HPAB-0276-CN-F(E) | Human Anti-IL10RA Recombinant Antibody; Fab Fragment (HPAB-0276-CN-F(E)) | ELISA, FC, Block, Neut | Human Fab |
HPAB-0277-CN-F(E) | Human Anti-IL10RA Recombinant Antibody; Fab Fragment (HPAB-0277-CN-F(E)) | ELISA, FC, Block, Neut | Human Fab |
HPAB-0278-CN-F(E) | Human Anti-IL10RA Recombinant Antibody; Fab Fragment (HPAB-0278-CN-F(E)) | ELISA, FC, Block, Neut | Human Fab |
CAT | Product Name | Application | Type |
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MOB-550-S(P) | Recombinant Anti-human IL10RA Antibody scFv Fragment | IF, FC, Biosensors, FuncS | scFv |
MHH-550-S(P) | Recombinant Human Anti-human IL10RA Antibody scFv Fragment | WB, IF, FuncS | scFv |
HPAB-0276-CN-S(P) | Human Anti-IL10RA Recombinant Antibody; scFv Fragment (HPAB-0276-CN-S(P)) | ELISA, FC, Block, Neut | Human scFv |
HPAB-0277-CN-S(P) | Human Anti-IL10RA Recombinant Antibody; scFv Fragment (HPAB-0277-CN-S(P)) | ELISA, FC, Block, Neut | Human scFv |
HPAB-0278-CN-S(P) | Human Anti-IL10RA Recombinant Antibody; scFv Fragment (HPAB-0278-CN-S(P)) | ELISA, FC, Block, Neut | Human scFv |
CAT | Product Name | Application | Type |
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AGTO-G039E | IL-10-PE immunotoxin | Cytotoxicity assay, Function study |
CAT | Product Name | Application | Type |
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NEUT-1132CQ | Rat Anti-IL10RA Recombinant Antibody (clone 3F9) | FC, IP, Block | Rat IgG2a, κ |
NEUT-1137CQ | Rat Anti-Il10ra Recombinant Antibody (NEUT-1137CQ) | Block, FC, IHC-Fr | Rat IgG2 |
NEUT-1138CQ | Rat Anti-Il10ra Recombinant Antibody (clone 1B1.3A) | Block, FC, WB | Rat IgG1 |
CAT | Product Name | Application | Type |
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NEUT-1133CQ | Mouse Anti-IL10RA Recombinant Antibody (clone CBL076) | WB, Neut | Mouse IgG2 |
NEUT-1134CQ | Mouse Anti-IL10RA Recombinant Antibody (clone CBL463) | Neut | Mouse IgG1 |
NEUT-1135CQ | Mouse Anti-IL10RA Recombinant Antibody (clone 7Q35) | Neut | Mouse IgG2 |
NEUT-1136CQ | Mouse Anti-IL10RA Recombinant Antibody (clone 37607.11) | Neut | Mouse IgG1 |
CAT | Product Name | Application | Type |
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VS-0225-XY126 | CytoStream™ Rat Anti-IL10RA Recombinant Antibody (clone 1B1.3a) | FC | Rat IgG1, kappa |
CAT | Product Name | Application | Type |
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VS-0325-FY25 | Human Anti-IL10RA (clone 136C5) scFv-Fc Chimera | ELISA, FC, Block, Neut | Human IgG1, scFv-Fc |
CAT | Product Name | Application | Type |
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VS-0525-XY3478 | Anti-IL10RA Immunohistochemistry Kit | IHC | |
VS-0525-XY3479 | Anti-Mouse IL10RA Immunohistochemistry Kit | IHC |
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