This immunotoxin was achieved by conjugating/fusing the IL-10 to Pseudomonas exotoxin. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to tumor cells. Once bind, the toxin enters cells by receptor-mediated endocytosis. Then PE cleaved fragments the size of Mr 37000 and 27000, the large fragment and finally into the Golgi and elongation factor 2 (EM) combining it glycosylation inactivation, inhibition of protein synthesis, leading to apoptosis. It was designed for treating peritonic tumor.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-550 | Recombinant Anti-human IL10RA Antibody | WB, ELISA, IHC, FuncS | IgG |
MHH-550 | Recombinant Human Anti-human IL10RA Antibody | ELISA, WB, Neut, FuncS | IgG |
MOB-0630CT | Recombinant Mouse anti-Human IL10RA Monoclonal antibody (48708.22) | ELISA, FC, Neut, WB | |
HPAB-0276-CN | Human Anti-IL10RA Recombinant Antibody (HPAB-0276-CN) | ELISA, FC, Block, Neut | Human IgG1 |
MOB-112LC | Rat Anti-IL10RA Recombinant Antibody (clone 3F9), PE | FC | Rat IgG2a |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-550-F(E) | Recombinant Anti-human IL10RA Antibody Fab Fragment | ELISA, RIA, FuncS | Fab |
MHH-550-F(E) | Recombinant Human Anti-human IL10RA Antibody Fab Fragment | WB, IF, FuncS | Fab |
HPAB-0276-CN-F(E) | Human Anti-IL10RA Recombinant Antibody; Fab Fragment (HPAB-0276-CN-F(E)) | ELISA, FC, Block, Neut | Human Fab |
HPAB-0277-CN-F(E) | Human Anti-IL10RA Recombinant Antibody; Fab Fragment (HPAB-0277-CN-F(E)) | ELISA, FC, Block, Neut | Human Fab |
HPAB-0278-CN-F(E) | Human Anti-IL10RA Recombinant Antibody; Fab Fragment (HPAB-0278-CN-F(E)) | ELISA, FC, Block, Neut | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-550-S(P) | Recombinant Anti-human IL10RA Antibody scFv Fragment | IF, FC, Biosensors, FuncS | scFv |
MHH-550-S(P) | Recombinant Human Anti-human IL10RA Antibody scFv Fragment | WB, IF, FuncS | scFv |
HPAB-0276-CN-S(P) | Human Anti-IL10RA Recombinant Antibody; scFv Fragment (HPAB-0276-CN-S(P)) | ELISA, FC, Block, Neut | Human scFv |
HPAB-0277-CN-S(P) | Human Anti-IL10RA Recombinant Antibody; scFv Fragment (HPAB-0277-CN-S(P)) | ELISA, FC, Block, Neut | Human scFv |
HPAB-0278-CN-S(P) | Human Anti-IL10RA Recombinant Antibody; scFv Fragment (HPAB-0278-CN-S(P)) | ELISA, FC, Block, Neut | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1132CQ | Rat Anti-IL10RA Recombinant Antibody (clone 3F9) | FC, IP, Block | Rat IgG2a, κ |
NEUT-1137CQ | Rat Anti-Il10ra Recombinant Antibody (clone mAb0852) | Block, FC, IHC-Fr | Rat IgG2 |
NEUT-1138CQ | Rat Anti-Il10ra Recombinant Antibody (clone 1B1.3A) | Block, FC, WB | Rat IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1133CQ | Mouse Anti-IL10RA Recombinant Antibody (clone CBL076) | WB, Neut | Mouse IgG2 |
NEUT-1134CQ | Mouse Anti-IL10RA Recombinant Antibody (clone CBL463) | Neut | Mouse IgG1 |
NEUT-1135CQ | Mouse Anti-IL10RA Recombinant Antibody (clone 7Q35) | Neut | Mouse IgG2 |
NEUT-1136CQ | Mouse Anti-IL10RA Recombinant Antibody (clone 37607.11) | Neut | Mouse IgG1 |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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