Recombinant Rabbit Anti-IL17F Detection Antibody (clone R07-2U4) (CAT#: VS3-WK1723)
This antibody is a rabbit recombinant antibody against human IL17F. It was developed by immunization of rabbit with recombinant human IL17F protein and then was produced as a recombinant antibody. The isotype of this product is rabbit IgG. R01-2O1 and R07-2U4 were identified as antibody pair for sandwich ELISA. As a detection antibody, the clone R07-2U4 can be used in ELISA analysis to identify human IL17F.
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
Specifications
- Immunogen
- Recombinant human IL17F protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human IL17F
- Species Reactivity
- Human
- Clone
- R07-2U4
- Applications
- ELISA
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Aggregation
- < 5%
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 0.01M PBS, pH 7.2
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- Interleukin 17F
- Gene ID
- 112744
- UniProt ID
- Q96PD4
- Long Name
- Interleukin 17F
- Sequence Similarities
- Belongs to the IL-17 family.
- Cellular Localization
- Secreted
- Protein Refseq
- NP_443104.1
- Function
- Effector cytokine of innate and adaptive immune system involved in antimicrobial host defense and maintenance of tissue integrity.
IL17A-IL17F signals via IL17RA-IL17RC heterodimeric receptor complex, triggering homotypic interaction of IL17RA and IL17RC chains with TRAF3IP2 adapter through SEFIR domains. This leads to downstream TRAF6-mediated activation of NF-kappa-B and MAPkinase pathways ultimately resulting in transcriptional activation of cytokines, chemokines, antimicrobial peptides and matrix metalloproteinases, with potential strong immune inflammation.
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Related Resources
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "IL17F"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-033ZJ | Anti-Human IL-17F Recombinant Antibody | ELISA, IP | |
TAB-033ZJ-S(P) | Anti-Human IL-17F Recombinant Antibody scFv Fragment | ELISA, IP | |
TAB-033ZJ-F(E) | Anti-Human IL-17F Recombinant Antibody Fab Fragment | ELISA, IP |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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