Recombinant Rabbit Anti-LEFTY2 Antibody (clone 10G2) (CAT#: VS4-CJ17)
This rabbit anti-LEFTY2 antibody (clone 10G2) is a product that recognizes human LEFTY2. The immunogen of this antibody is a synthesized peptide derived from human LEFTY2. The mAb has been tested for use in ELISA, Western Blot (1:500-1:2000).
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Normal Tissue
RNA Expression
Figure 1 IHC staining of human rectum
(Immunohistochemical staining of human rectum shows strong positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47883/ihc_selected.jpg
(Immunohistochemical staining of human rectum shows strong positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47883/ihc_selected.jpg
Figure 2 IHC staining of human tonsil
(Immunohistochemical staining of human tonsil shows strong cytoplasmic positivity in lymphoid cells outside the reaction centra.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/25801/ihc_selected.jpg
(Immunohistochemical staining of human tonsil shows strong cytoplasmic positivity in lymphoid cells outside the reaction centra.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/25801/ihc_selected.jpg
Figure 3 Cerebral cortex
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/56210/126863_B_8_5.jpg
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/56210/126863_B_8_5.jpg
Figure 4 Colon
(Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47883/116892_A_8_3.jpg
(Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47883/116892_A_8_3.jpg
Figure 5 Liver
(Cholangiocytes
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/25801/58819_A_7_4.jpg
(Cholangiocytes
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/25801/58819_A_7_4.jpg
Figure 6 Kidney
(Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47883/116892_A_8_5.jpg
(Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47883/116892_A_8_5.jpg
Figure 7 Testis
(Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47883/116892_A_5_6.jpg
(Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47883/116892_A_5_6.jpg
Figure 8 Smooth muscle
(Smooth muscle cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47883/116892_B_5_7.jpg
(Smooth muscle cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47883/116892_B_5_7.jpg
Figure 9 Lymph node
(Non-germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/25801/58819_A_8_8.jpg
(Non-germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/25801/58819_A_8_8.jpg
Figure 10 RNA cell line category: Cell line enhanced (HDLM-2, NTERA-2, RPMI-8226, SuSa)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000143768-LEFTY2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000143768-LEFTY2
Specifications
- Immunogen
- A synthesized peptide derived from human LEFTY2
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human LEFTY2
- Species Reactivity
- Human
- Clone
- 10G2
- Applications
- ELISA, WB
- Conjugate
- Unconjugated
Product Property
- Purification
- Affinity chromatography
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- 50% Glycerol, 150 mM NaCl, PBS, pH 7.4.
- Preservative
- 0.02% Sodium Azide
- Storage
- Store at -20°C or -80°C upon receipt. Avoid repeated freeze.
Applications
- Application Notes
- This antibody has been tested for use in ELISA, Western Blot (1:500-1:2000).
Target
- Alternative Names
- EBAF; LEFTA; TGFB4; LEFTYA
- Gene ID
- 7044
- UniProt ID
- O00292
- Long Name
- Left-right determination factor 2
- Sequence Similarities
- Belongs to the TGF-beta family
- Cellular Localization
- Secreted
- Post Translation Modifications
- The processing of the protein may also occur at the second R-X-X-R site located at AA 132-135. Processing appears to be regulated in a cell-type specific manner.
- Protein Refseq
- NP_001165896.1; NP_003231.2
- Function
- Required for left-right (L-R) asymmetry determination of organ systems in mammals. May play a role in endometrial bleeding.
Recommended Products
Isotype Control
Secondary Antibody
Recommended Dilution Buffer
Related Resources
TGF-β Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
Rabbit Monoclonal Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1082CT | Recombinant Mouse anti-Human LEFTY2 Monoclonal antibody (182515) | ELISA, WB |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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