Recombinant Anti-LILRA4 Vesicular Antibody, EV Displayed (VS-0425-YC459) (CAT#: VS-0425-YC459)
The Recombinant Anti-LILRA4 Vesicular Antibody, EV Displayed (VS-0425-YC459) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to LILRA4-expressed cells or tissues. The LILRA4 is a protein influencing dendritic cell function in the immune response, with expression modulated by interleukin 3.
Specific Inquiry
Subcellular Location and Protein Expression
Normal Tissue
Figure 1 IHC staining of human lymph node
(Immunohistochemical staining of human lymph node shows strong cytoplasmic positivity in non-germinal center cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49418/118151_A_7_8_selected.jpg
(Immunohistochemical staining of human lymph node shows strong cytoplasmic positivity in non-germinal center cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49418/118151_A_7_8_selected.jpg
Figure 2 Colon
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49418/118151_A_7_3.jpg
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49418/118151_A_7_3.jpg
Figure 3 Kidney
(Cells in glomeruli
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49418/118151_A_7_5.jpg
(Cells in glomeruli
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49418/118151_A_7_5.jpg
Figure 4 Testis
(Elongated or late spermatids
Staining: High
Intensity: Strong
Quantity:>75%
Round or early spermatids
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49418/118151_A_5_6.jpg
(Elongated or late spermatids
Staining: High
Intensity: Strong
Quantity:>75%
Round or early spermatids
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49418/118151_A_5_6.jpg
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- LILRA4
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human, Cynomolgus
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Leukocyte immunoglobulin like receptor A4
- Biological Process
- Immunity, Innate immunity
- Molecular Function
- Receptor
- Introduction
- This gene encodes an immunoglobulin-like cell surface protein that is expressed predominantly on plasmacytoid dendritic cells (PDCs) and modulates the function of these cells in the immune response. Expression of this gene is downregulated by interleukin 3 (IL3).
- Alternative Names
- CD85g, ILT7
- Gene ID
- 23547
- UniProt ID
- P59901
Downloads
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ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1095CT | Recombinant Mouse anti-Human LILRA4 Monoclonal antibody (28H20.3) | FC | |
| FN-194CQ | Recombinant Mouse Anti-LILRA4 Antibody (17G10.2) | FC, FuncS, IP | Mouse IgG1 |
| HPAB-N0168-YC | Human Anti-LILRA4 Recombinant Antibody (HPAB-N0168-YC) | FC, ELISA, FuncS | Humanized IgG1 |
| VS3-FY2605 | Mouse Anti-LILRA4 Recombinant Antibody (VS3-FY2605) | IHC, FC, ELISA | Mouse IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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