Human Anti-LILRA4 scFv-Fc Chimera (VS-0325-FY103) (CAT#: VS-0325-FY103)

• Host Species
• Human

• Type
• Human IgG1, scFv-Fc

• Specificity
• Human LILRA4

• Species Reactivity
• Human

• Applications
• Flow Cytometry

• Related Disease
• Cancer, autoimmune disease

• Purity
• >95% as determined by SDS-PAGE

• Concentration
• Please refer to the vial label for the specific concentration.

• Storage
• Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

• Shipping
• Ice packs

• Alternative Names
• ILT7; CD85g

• Gene ID
• 23547

• Long Name
• leukocyte immunoglobulin like receptor A4

• Cellular Localization
• Cell membrane

• Post Translation Modifications
• Glycosylation at Asn138, Asn239, Asn279, and Asn300
  Modification sites at PhosphoSitePlus
  Glycosylation from GlyGen 4 sites

• Protein Refseq
• NP_036408.4

• Function
• Functions coreceptor to limit the innate immune responses to viral infections; signaling occurs via FCER1G (PubMed:16735691, 19564354).
  Down-regulates the production of IFNA1, IFNA2, IFNA4, IFNB1 and TNF by plasmacytoid dendritic cells that have been exposed to influenza virus or cytidine-phosphate-guanosine (CpG) dinucleotides, indicating it functions as a negative regulator of TLR7 and TLR9 signaling cascades.

Isotype Control

• MOB-200CQ
• Human IgG Fc Isotype Control Antibody

Secondary Antibody

• 2ND-029CQ
• Goat Anti-Human IgG Fc Antibody

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