Mouse Anti-LILRA4 Recombinant Antibody (VS3-FY2605) (CAT#: VS3-FY2605)

The anti-LILRA4 antibody is a mouse recombinant monoclonal antibody, which has been intricately crafted to target the leukocyte immunoglobulin like receptor A4. The calculated molecular weight of the protein is 55.2 kDa. It exhibits cross-reactivity with human. This monoclonal antibody is potential for conducting research on Pitt-Hopkins Syndrome. The antibody can be utilized for detection of LILRA4 by Immunohistochemistry, Flow cytometry, ELISA.

Sub Cat Application Application Notes Size Conjugation Endotoxin Purity Fc Engineering  
VS3-FY2772 IHC, FC, ELISA Immunohistochemistry: 1/50-1/200
Flow cytometry: 1/50-1/200
ELISA: 1/1000-1/10000
VS3-FY2606 WB, ICC, FC, ELISA Western Blot: 1/500-1/2000
Immunocytochemistry: 1/50-1/200
Flow cytometry: 1/50-1/200
ELISA: 1/1000-1/10000
More Infomation
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location and Protein Expression
Normal Tissue

Specifications

  • Host Species
  • Mouse
  • Type
  • Mouse IgG
  • Specificity
  • leukocyte immunoglobulin like receptor A4 of human
  • Species Reactivity
  • Human
  • Conjugate
  • Unconjugated, FITC
  • MW
  • The molecular weight of the target protein is approximately 55.2 kDa.
  • Related Disease
  • Pitt-Hopkins Syndrome

Product Property

  • Clonality
  • Monoclonal Antibody
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • ILT7; CD85g
  • Cellular Localization
  • Cell membrane
  • Post Translation Modifications
  • Glycosylation at Asn138, Asn239, Asn279, and Asn300
    Modification sites at PhosphoSitePlus
    Glycosylation from GlyGen 4 sites
  • Function
  • Functions coreceptor to limit the innate immune responses to viral infections; signaling occurs via FCER1G (PubMed:16735691, 19564354).
    Down-regulates the production of IFNA1, IFNA2, IFNA4, IFNB1 and TNF by plasmacytoid dendritic cells that have been exposed to influenza virus or cytidine-phosphate-guanosine (CpG) dinucleotides, indicating it functions as a negative regulator of TLR7 and TLR9 signaling cascades.

Recommended Products

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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