Mouse Anti-LILRA4 Recombinant Antibody (VS3-FY2605)
CAT#: VS3-FY2605
The anti-LILRA4 antibody is a mouse recombinant monoclonal antibody, which has been intricately crafted to target the leukocyte immunoglobulin like receptor A4. The calculated molecular weight of the protein is 55.2 kDa. It exhibits cross-reactivity with human. This monoclonal antibody is potential for conducting research on Pitt-Hopkins Syndrome. The antibody can be utilized for detection of LILRA4 by Immunohistochemistry, Flow cytometry, ELISA.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IHC staining of human lymph node
Immunohistochemical staining of human lymph node shows strong cytoplasmic positivity in non-germinal center cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/49418/118151_A_7_8_selected.jpg
Normal Tissue
Figure 2 Colon
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/49418/118151_A_7_3.jpg
Normal Tissue
Figure 3 Kidney
Cells in glomeruli
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/49418/118151_A_7_5.jpg
Normal Tissue
Figure 4 Testis
Elongated or late spermatids
Staining: High
Intensity: Strong
Quantity:>75%
Round or early spermatids
Staining: High
Intensity: Strong
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/49418/118151_A_5_6.jpg
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| Sub Cat | Application | Application Notes | Size | Conjugation | Endotoxin | Purity | Fc Engineering | |
| VS3-FY2772 | IHC, FC, ELISA |
Immunohistochemistry: 1/50-1/200 Flow cytometry: 1/50-1/200 ELISA: 1/1000-1/10000 |
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| VS3-FY2606 | WB, ICC, FC, ELISA |
Western Blot: 1/500-1/2000 Immunocytochemistry: 1/50-1/200 Flow cytometry: 1/50-1/200 ELISA: 1/1000-1/10000 |
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- leukocyte immunoglobulin like receptor A4 of human
- Species Reactivity
- Human
- Conjugate
- Unconjugated, FITC
- MW
- The molecular weight of the target protein is approximately 55.2 kDa.
- Related Disease
- Pitt-Hopkins Syndrome
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- ILT7; CD85g
- Gene ID
- 23547
- Cellular Localization
- Cell membrane
- Post Translation Modifications
- Glycosylation at Asn138, Asn239, Asn279, and Asn300
Modification sites at PhosphoSitePlus
Glycosylation from GlyGen 4 sites
- Protein Refseq
- NP_036408.4
- Function
- Functions coreceptor to limit the innate immune responses to viral infections; signaling occurs via FCER1G (PubMed:16735691, 19564354).
Down-regulates the production of IFNA1, IFNA2, IFNA4, IFNB1 and TNF by plasmacytoid dendritic cells that have been exposed to influenza virus or cytidine-phosphate-guanosine (CpG) dinucleotides, indicating it functions as a negative regulator of TLR7 and TLR9 signaling cascades.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "LILRA4"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1095CT | Recombinant Mouse anti-Human LILRA4 Monoclonal antibody (28H20.3) | FC | |
| FN-194CQ | Recombinant Mouse Anti-LILRA4 Antibody (17G10.2) | FC, FuncS, IP | Mouse IgG1 |
| HPAB-N0168-YC | Human Anti-LILRA4 Recombinant Antibody (HPAB-N0168-YC) | FC, ELISA, FuncS | Humanized IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0168-YC-S(P) | Human Anti-LILRA4 Recombinant Antibody; scFv Fragment (HPAB-N0168-YC-S(P)) | FC, ELISA, FuncS | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0168-YC-F(E) | Human Anti-LILRA4 Recombinant Antibody; Fab Fragment (HPAB-N0168-YC-F(E)) | FC, ELISA, FuncS | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY103 | Human Anti-LILRA4 scFv-Fc Chimera (VS-0325-FY103) | FC | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC459 | Recombinant Anti-LILRA4 Vesicular Antibody, EV Displayed (VS-0425-YC459) | ELISA, FC, Cell-uptake |
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