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LILRA4

Anti-LILRA4 Products

Afuco™ Anti-Human LILRA4 ADCC Recombinant Antibody, ADCC Enhanced (AFC-471CL)
- Species Reactivity: Human
- Type: ADCC enhanced antibody
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Recombinant Mouse anti-Human LILRA4 Monoclonal antibody (28H20.3) (MOB-1095CT)
- Species Reactivity: Human
- Application: FC
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Recombinant Mouse Anti-LILRA4 Antibody (17G10.2) (FN-194CQ)
- Species Reactivity: Non-human primate, Human
- Type: Mouse IgG1
- Application: FC, FuncS, IP
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Human Anti-LILRA4 Recombinant Antibody (HPAB-N0168-YC) (HPAB-N0168-YC)
- Derivation: Humanized
- Species Reactivity: Human, Cynomolgus monkey
- Type: Humanized IgG1
- Application: FC, ELISA, FuncS
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Human Anti-LILRA4 Antibody, mRNA (TAB-491CL-mRNA)
- Species Reactivity: Human
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Mouse Anti-LILRA4 Recombinant Antibody (VS3-FY2605) (VS3-FY2605)
- Species Reactivity: Human
- Type: Mouse IgG
- Application: IHC, FC, ELISA
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Human Anti-LILRA4 Recombinant Antibody; scFv Fragment (HPAB-N0168-YC-S(P)) (HPAB-N0168-YC-S(P))
- Derivation: Humanized
- Species Reactivity: Human, Cynomolgus monkey
- Type: Humanized scFv
- Application: FC, ELISA, FuncS
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Human Anti-LILRA4 Recombinant Antibody; Fab Fragment (HPAB-N0168-YC-F(E)) (HPAB-N0168-YC-F(E))
- Derivation: Humanized
- Species Reactivity: Human, Cynomolgus monkey
- Type: Humanized Fab
- Application: FC, ELISA, FuncS
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Anti-Human LILRA4 Recombinant Antibody (TAB-491CL)
- Species Reactivity: Human
- Type: Antibody
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Human Anti-LILRA4 scFv-Fc Chimera (VS-0325-FY103) (VS-0325-FY103)
- Species Reactivity: Human
- Type: Human IgG1, scFv-Fc
- Application: FC
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Recombinant Anti-LILRA4 Vesicular Antibody, EV Displayed (VS-0425-YC459) (VS-0425-YC459)
- Species Reactivity: Human, Cynomolgus
- Target: LILRA4
- Host Animal: Human
- Application: ELISA, FC, Cell-uptake
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For Research Use Only. Not For Clinical Use.

This gene encodes an immunoglobulin-like cell surface protein that is expressed predominantly on plasmacytoid dendritic cells (PDCs) and modulates the function of these cells in the immune response. Expression of this gene is downregulated by interleukin 3 (IL3).

Protein class

CD markers

Predicted location

Membrane

Single cell type specificity

Cell type enriched (dendritic cells)

Immune cell specificity

Immune cell enriched (plasmacytoid DC)

Cell line specificity

Not detected

Interaction

Interacts with FCER1G; this stabilizes the expression of both proteins at the cell membrane (PubMed:16735691). Interacts with BST2; leads to activation of LILRA4-mediated signaling and down-regulation of the innate immune response to viral pathogens (PubMed:19564354, 26172439).

Molecular function

Receptor

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