Recombinant Anti-LYPD3 Vesicular Antibody, EV Displayed (VS-0425-YC487)

CAT#: VS-0425-YC487

The Recombinant Anti-LYPD3 Vesicular Antibody, EV Displayed (VS-0425-YC487) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to LYPD3-expressed cells or tissues. LYPD3 is involved in laminin binding and regulation of smooth muscle cell apoptosis. This protein is located extracellularly.

Gene Expression
Figure 1 IF staining of human cell line RT4 Figure 2 IHC staining of human skin Figure 3 IHC staining of human kidney Figure 4 IHC staining of human esophagus Figure 5 IHC staining of human skeletal muscle Figure 6 Cerebral cortex Figure 7 Colon Figure 8 Testis Figure 9 Lymph node Figure 10 RNA cell line category: Cell line enhanced (CAPAN-2, HaCaT, MCF7, RT4, SK-BR-3)

Recombinant Antibody

  • Application
  • ELISA, FC, Cell-uptake
  • Product Type
  • Ab-Fc-EVs
  • Antibody Quantification (Ab/EV)
  • ~100 Ab/EV
  • Target
  • LYPD3
  • Host Animal
  • Human
  • Antibody Isotype
  • IgG
  • Species Reactivity
  • Human, Mouse
  • Expression Cell
  • Mammalian cell

Engineered EVs

  • EV-sorting domain
  • CD63
  • Fc-binding domain
  • z domain
  • EV Size
  • 30~150 nm
  • Producing Cell
  • HEK293F
  • Isolation Method
  • Gradient centrifugation
  • Purification
  • qEV size exclusion chromatography
  • Binding Affinity
  • Kd = 0.85 µg/mL
  • Concentration
  • 1 x 10¹⁰
  • Size
  • 1 mL
  • Buffer
  • PBS
  • Storage
  • Store at -80°C for 12 months

Target

  • Full Name
  • LY6/PLAUR domain containing 3
  • Cellular Localization
  • Endoplasmic reticulum, Vesicles
  • Introduction
  • Predicted to enable laminin binding activity. Involved in negative regulation of smooth muscle cell apoptotic process. Located in extracellular space.
  • Alternative Names
  • C4.4A
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VS-0425-FY148 Mouse Anti-LYPD3 scFv-Fc Chimera (VS-0425-FY148) ELISA, Block Mouse IgG2b, scFv-Fc
CAT Product Name Application Type
VS-0525-XY4144 Anti-LYPD3 Immunohistochemistry Kit IHC
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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