Recombinant Anti-LYPD3 Vesicular Antibody, EV Displayed (VS-0425-YC487)
CAT#: VS-0425-YC487
The Recombinant Anti-LYPD3 Vesicular Antibody, EV Displayed (VS-0425-YC487) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to LYPD3-expressed cells or tissues. LYPD3 is involved in laminin binding and regulation of smooth muscle cell apoptosis. This protein is located extracellularly.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line RT4
Immunofluorescent staining of human cell line RT4 shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/77859/1748_H2_22_cr5805e03b68159_selected.jpg
Normal Tissue
Figure 2 IHC staining of human skin
High expression. RNA expression: 669.3 nTPM
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/41529/88166_B_7_1_val_selected.jpg
Normal Tissue
Figure 3 IHC staining of human kidney
Low expression. RNA expression: 2.9 nTPM
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/41529/88166_A_8_5_val_selected.jpg
Normal Tissue
Figure 4 IHC staining of human esophagus
High expression. RNA expression: 1066.8 nTPM
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/41797/88184_B_5_1_val_selected.jpg
Normal Tissue
Figure 5 IHC staining of human skeletal muscle
Low expression. RNA expression: 2.8 nTPM
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/41797/88184_B_2_6_val_selected.jpg
Normal Tissue
Figure 6 Cerebral cortex
Neuronal cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranou
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/41797/88184_B_8_5.jpg
Normal Tissue
Figure 7 Colon
Glandular cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/41797/88184_A_7_3.jpg
Normal Tissue
Figure 8 Testis
Leydig cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/41797/88184_A_6_6.jpg
Normal Tissue
Figure 9 Lymph node
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/41797/88184_A_8_8.jpg
RNA Expression
Figure 10 RNA cell line category: Cell line enhanced (CAPAN-2, HaCaT, MCF7, RT4, SK-BR-3)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000124466-LYPD3
❮
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- LYPD3
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human, Mouse
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- LY6/PLAUR domain containing 3
- Cellular Localization
- Endoplasmic reticulum, Vesicles
- Introduction
- Predicted to enable laminin binding activity. Involved in negative regulation of smooth muscle cell apoptotic process. Located in extracellular space.
- Alternative Names
- C4.4A
- Gene ID
- 27076
- UniProt ID
- O95274
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Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2109 | Hi-Affi™ Recombinant Rabbit Anti-LYPD3 Monoclonal Antibody (DS2109AB) | ELISA | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4318 | Hi-Affi™ Recombinant Rabbit Anti-LYPD3 Monoclonal Antibody (SI407DS) | FC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4319 | Hi-Affi™ Recombinant Rabbit Anti-LYPD3 Monoclonal Antibody (SI408DS) | WB, ELISA, ICC, IF, IF, FC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4320 | Hi-Affi™ Recombinant Rabbit Anti-LYPD3 Monoclonal Antibody (SI409DS) | FC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0032CQ | Human Anti-LYPD3 Recombinant Antibody (HPAB-0032CQ) | ELISA, WB, FC, FuncS | Human IgG1, λ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0033CQ | Human Anti-LYPD3 Recombinant Antibody (HPAB-0033CQ) | ELISA, WB, FC, IF, FuncS | Human IgG1, λ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0032CQ-S(P) | Human Anti-LYPD3 Recombinant Antibody scFv Fragment (HPAB-0032CQ-S(P)) | ELISA, WB, FC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0033CQ-S(P) | Human Anti-LYPD3 Recombinant Antibody scFv Fragment (HPAB-0033CQ-S(P)) | ELISA, WB, FC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0032CQ-F(E) | Human Anti-LYPD3 Recombinant Antibody Fab Fragment (HPAB-0032CQ-F(E)) | ELISA, WB, FC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0033CQ-F(E) | Human Anti-LYPD3 Recombinant Antibody Fab Fragment (HPAB-0033CQ-F(E)) | ELISA, WB, FC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1553LY-S(P) | Mouse Anti-LYPD3 Recombinant Antibody; scFv Fragment (HPAB-1553LY-S(P)) | IHC | Mouse scfv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1554LY-S(P) | Mouse Anti-LYPD3 Recombinant Antibody; scFv Fragment (HPAB-1554LY-S(P)) | IHC | Mouse scfv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1555LY-S(P) | Mouse Anti-LYPD3 Recombinant Antibody; scFv Fragment (HPAB-1555LY-S(P)) | IHC | Mouse scfv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1553LY | Mouse Anti-LYPD3 Recombinant Antibody (HPAB-1553LY) | IHC | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1554LY | Mouse Anti-LYPD3 Recombinant Antibody (HPAB-1554LY) | IHC | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1555LY | Mouse Anti-LYPD3 Recombinant Antibody (HPAB-1555LY) | IHC | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1553LY-F(E) | Mouse Anti-LYPD3 Recombinant Antibody; Fab Fragment (HPAB-1553LY-F(E)) | IHC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1554LY-F(E) | Mouse Anti-LYPD3 Recombinant Antibody; Fab Fragment (HPAB-1554LY-F(E)) | IHC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1555LY-F(E) | Mouse Anti-LYPD3 Recombinant Antibody; Fab Fragment (HPAB-1555LY-F(E)) | IHC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY148 | Mouse Anti-LYPD3 scFv-Fc Chimera (VS-0425-FY148) | ELISA, Block | Mouse IgG2b, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4144 | Anti-LYPD3 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0825-YC245 | SmartAb™ Recombinant Anti-LYPD3 pH-dependent Antibody (VS-0825-YC245) | ELISA, WB, FC | Human IgG1 lambda |
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