Recombinant Anti-MERTK Vesicular Antibody, EV Displayed (VS-0425-YC607)
CAT#: VS-0425-YC607
The Recombinant Anti-MERTK Vesicular Antibody, EV Displayed (VS-0425-YC607) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to MERTK-expressed cells or tissues. MERTK is a receptor kinase essential for retinal pigment epithelium (RPE) phagocytosis. Mutations lead to retinitis pigmentosa, affecting photoreceptor cell maintenance.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & endoplasmic reticulum.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/75622/1740_F11_62_selected.jpg
Normal Tissue
Figure 2 Adrenal gland
Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/36196/75498_B_6_5.jpg
Normal Tissue
Figure 3 Liver
Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/36196/75498_A_9_4.jpg
Normal Tissue
Figure 4 Kidney
Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/36196/75498_A_8_5.jpg
Normal Tissue
Figure 5 Testis
Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Spermatogonia cells Staining: High Intensity: Strong
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/36196/75498_A_4_6.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (CACO-2, Hep G2, HUVEC TERT2, RT4)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000153208-MERTK
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- MERTK
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human, Mouse
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- MER proto-oncogene, tyrosine kinase
- Molecular Function
- Kinase, Receptor, Transferase, Tyrosine-protein kinase
- Cellular Localization
- Plasma membrane, Midbody, Cytosol, Acrosome, Mid piece, Principal piece
- Introduction
- This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).
- Alternative Names
- c-Eyk, mer, RP38, Tyro12
- Gene ID
- 10461
- UniProt ID
- Q12866
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS-0425-YC607. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "MERTK"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1725CQ | Recombinant Mouse Anti-MERTK Antibody (NEUT-1725CQ) | BL, WB, IP, IHC-P | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2214 | Hi-Affi™ Recombinant Rabbit Anti-MERTK Monoclonal Antibody (DS2214AB) | WB, IHC, IP, FC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0215-CN-S(P) | Mouse Anti-MERTK Recombinant Antibody; scFv Fragment (HPAB-0215-CN-S(P)) | WB, ELISA | Mouse scFv |
| HPAB-0216-CN-S(P) | Mouse Anti-MERTK Recombinant Antibody; scFv Fragment (HPAB-0216-CN-S(P)) | WB, ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0215-CN-F(E) | Mouse Anti-MERTK Recombinant Antibody; Fab Fragment (HPAB-0215-CN-F(E)) | WB, ELISA | Mouse Fab |
| HPAB-0216-CN-F(E) | Mouse Anti-MERTK Recombinant Antibody; Fab Fragment (HPAB-0216-CN-F(E)) | WB, ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-0988-CN | Recombinant Rabbit Anti-MERTK Monoclonal Antibody (CBACN-367) | WB, IHC, IP | Rabbit IgG |
| ZG-0280C | Mouse Anti-MERTK Recombinant Antibody (ZG-0280C) | WB, ELISA | Mouse IgG |
| VS1-YJ136 | Mouse Anti-MERTK Recombinant Antibody (clone A311F9G3) | WB | Mouse IgG1, κ |
| VS3-WK909 | Rabbit Anti-MERTK Recombinant Antibody (VS3-WK909) | WB, IHC, IP | Rabbit IgG |
| VS7-0425-WR377 | Mouse Anti-MERTK Recombinant Antibody (clone 3D11G8) | WB, ICC, FC | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY31 | Mouse Anti-MERTK scFv-Fc Chimera (VS-0325-FY31) | Inhib | Mouse IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4354 | Anti-Mouse MERTK Immunohistochemistry Kit | IHC |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: WB, IF, IP, Neut, FuncS, ELISA, FC
Application: FC, IP, ELISA, Neut, FuncS, IF, WB
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: FC, IHC, FuncS, Inhib, Cyt
Application: WB, IF, FuncS
-2-1.png)
Application: ELISA
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: ELISA, IHC, WB
Application: ELISA, FuncS, RIA, IP, IF, IHC, IA, Block
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
