Anti-MERTK Recombinant Antibody Products

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Anti-MERTK Products

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For Research Use Only. Not For Clinical Use.

Creative Biolabs offers advanced recombinant antibodies targeting MERTK, supporting the progress of biomedical research. Through cutting-edge technology platforms, we ensure each product upholds strict standards of quality and performance. Our broad portfolio reflects a strong commitment to research advancement, delivering reliable and cost-effective solutions. In addition to high-performance antibodies, we provide expert technical assistance to support scientists throughout their projects. Partnering with Creative Biolabs means gaining access to innovative tools and a dependable ally in your research efforts.

MERTK: A Crucial target in Autoimmune Disorders and Inflammatory Diseases

MERTK is a receptor tyrosine kinase that plays a critical role in immune regulation, tissue homeostasis, and the clearance of apoptotic cells. Dysregulation or overexpression of MERTK has been implicated in various diseases, including cancers such as leukemia and non-small cell lung cancer, as well as autoimmune and inflammatory disorders like systemic lupus erythematosus and rheumatoid arthritis. In cancer, MERTK contributes to tumor growth, survival, and resistance to therapy by promoting immune evasion and supporting oncogenic signaling pathways. In autoimmune diseases, improper MERTK signaling can impair the removal of dying cells, leading to chronic inflammation. Due to its involvement in both immune dysfunction and tumor progression, MERTK is considered a promising therapeutic target in oncology and immunology.

Alternative Names

Complement MERTK; MER proto-oncogene, tyrosine kinase; MER; RP38; c-Eyk; c-mer; Tyro12

Background

This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).

Anti-MERTK rAb Products

We are dedicated to advancing research and innovation by delivering high-quality anti-MERTK recombinant antibodies, combined with strong technical support and cost-effective solutions. Our goal is to help researchers move their projects forward efficiently and with confidence.

Creative Quality Control

To support the advancement of biopharmaceutical research through to commercialization, we prioritize a customer-focused approach, emphasizing the delivery of high-quality products. A robust quality management system has been established to ensure consistency and reliability. By consistently meeting — and often exceeding — customer expectations, we strive to streamline the drug development process and help our clients reduce time to market.

Customer Reviews

Excellent

S**ia
Human Anti-MERTK Recombinant Antibody (clone 8H11) (CAT#: ZG-0138U)

It performs well in detecting MERTK expression in HEK293 and A549 cell lines. I've used it in both ELISA and Western blot with good results—clear, specific bands and minimal background. It also works well in immunohistochemistry, although some optimization was required for certain tissues. Overall, it is reliable and provides consistent, reproducible results without being too expensive.

12/Mar/2024

Excellent

B**in
Mouse Anti-MERTK Recombinant Antibody (clone 28A5) (CAT#: MOB-4080z)

I tested it on THP-1 and RAW264.7 cells and found it worked well. It produced distinct, specific bands in both ELISA and Western blot, with minimal background noise. The antibody also worked on tissue samples, though some parameter tuning was necessary. Overall, it showed dependable and consistent performance.

18/Nov/2023

rAb Production

With years of experience in recombinant antibody development and optimization, we are committed to delivering high-quality products and efficient service. Our focus on excellence ensures reliable recombinant antibodies within a short turnaround time.

Featured Anti-MERTK Recombinant Antibody Production Platforms
Fig.2 Milligram-scale recombinant antibody production.

Fig.3 Gram-scale recombinant antibody production.

rAb Modalities

Creative Biolabs provides researchers with a broad selection of advanced, high-quality recombinant antibodies in multiple formats. We specialize in diverse antibody engineering techniques and offer customized services to meet specific project requirements.

Fig.4 Full Length Anti-MERTK Recombinant Antibody Production and Modalities.

Drug Information Targeting MERTK

Table 1. Therapeutic approaches targeting MERTK in clinical development.

If you need more details about the MERTK target, don't hesitate to contact us by phone or email. Our experienced team is happy to help with any questions or issues you encounter, providing the support necessary for your research success.