Recombinant Anti-PERP Vesicular Antibody, EV Displayed (VS-0425-YC278) (CAT#: VS-0425-YC278)
The Recombinant Anti-PERP Vesicular Antibody, EV Displayed (VS-0425-YC278) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to PERP-expressed cells or tissues. The PERP is involved in processes like endopeptidase activity and neutrophil chemotaxis, associated with skin conditions.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Skin
(Cells in corneal layer
Staining:High
Intensity: Strong
Quantity:>75%
Cells in granular layer
Staining:Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/22269/51287_B_9_1.jpg
(Cells in corneal layer
Staining:High
Intensity: Strong
Quantity:>75%
Cells in granular layer
Staining:Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/22269/51287_B_9_1.jpg
Figure 2 RNA cell line category: Cell line enhanced (hTCEpi)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000112378-PERP
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000112378-PERP
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- PERP
- Host Animal
- Human
- Antibody Isotype
- IgG
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- P53 apoptosis effector related to PMP22
- Biological Process
- Apoptosis, Cell adhesion
- Introduction
- Involved in activation of cysteine-type endopeptidase activity and positive regulation of neutrophil chemotaxis. Predicted to be located in desmosome and plasma membrane. Predicted to be active in cell-cell junction. Implicated in erythrokeratodermia variabilis and mutilating palmoplantar keratoderma with periorificial keratotic plaques.
- Alternative Names
- dJ496H19.1, KCP1, KRTCAP1, PIGPC1, THW
- Gene ID
- 64065
- UniProt ID
- Q96FX8
Downloads
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Mouse Antibody Products
Chimeric Antibody Products
Rabbit Monoclonal Antibody Products
IgG Antibody Products
Hexamer Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1017CL | Anti-Human PERP Recombinant Antibody (KM3411) | FC | |
| TAB-1017CL-S(P) | Anti-Human PERP Recombinant Antibody scFv Fragment (KM3411) | SDS-PAGE, FC | |
| TAB-1017CL-F(E) | Anti-Human PERP Recombinant Antibody Fab Fragment (KM3411) | SDS-PAGE, FC |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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