Recombinant Anti-PROM1 Vesicular Antibody, EV Displayed (VS-0425-YC266)
CAT#: VS-0425-YC266
The Recombinant Anti-PROM1 Vesicular Antibody, EV Displayed (VS-0425-YC266) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to PROM1-expressed cells or tissues. The PROM1 is a glycoprotein maintaining stem cell properties and associated with retinal diseases and cancer.
Gene Expression
Normal Tissue
Figure 1 Colon
Goblet cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4922/15212_A_8_3.jpg
Normal Tissue
Figure 2 Liver
Cholangiocytes
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4922/15212_A_7_4.jpg
Normal Tissue
Figure 3 Pancreas
Exocrine glandular cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4922/15212_A_2_3.jpg
Normal Tissue
Figure 4 Kidney
Bowman's capsule
Staining:High
Intensity: Strong
Quantity:>75%
Distal tubules
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Proximal tubules (cell body)
Staining:Medium
Intensity: Strong
Quantity: <25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4922/15212_A_8_5.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (AF22, CACO-2, CAPAN-2, EFO-21, NTERA-2, RPTEC TERT1)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000007062-PROM1
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- PROM1
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Prominin 1
- Cellular Localization
- Plasma membrane
- Introduction
- This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner.
- Alternative Names
- AC133, CD133, CORD12, MCDR2, PROML1, RP41, STGD4
- Gene ID
- 8842
- UniProt ID
- O43490
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Datasheet
MSDS
COA
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Lot Number:
See other products for "PROM1"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B028(A) | Recombinant Anti-human PROM1 Intrabody [(D-Arg)9] | ELISA, Neut, FuncS | scFv-(D-Arg)9 |
| IAB-B028(G) | Recombinant Anti-human PROM1 Intrabody [+36 GFP] | PCA, WB, FuncS | scFv-(+36GFP) |
| IAB-B028(T) | Recombinant Anti-human PROM1 Intrabody [Tat] | FACS, ELISA, IF, FuncS | scFv-Tat |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G057S | Anti-PROM1 immunotoxin (scFv)-Sap | Cytotoxicity assay, Function study |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0375CL-F(E) | Anti-Mouse PROM1 Recombinant Antibody Fab Fragment (293AC1C3H9) | FC | Chimeric (mouse/human) |
| TAB-0376CL-F(E) | Anti-Mouse PROM1 Recombinant Antibody Fab Fragment (SDIE 293) | FC | Chimeric (mouse/human) |
| TAB-0377CL-F(E) | Anti-Mouse PROM1 Recombinant Antibody Fab Fragment (W6B3H10) | FC | Chimeric (mouse/human) |
| TAB-1074CL-F(E) | Anti-Human PROM1 Recombinant Antibody Fab Fragment (AC133) | ELISA | |
| TAB-1075CL-F(E) | Mouse Anti-PROM1 Recombinant Antibody; Fab Fragment (TAB-1075CL-F(E)) | WB, IF, FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0183-YC | Human Anti-PROM1 Recombinant Antibody (clone h133H/h133La) | ELISA, FC | Humanized IgG |
| HPAB-0088-FY | Human Anti-PROM1 Recombinant Antibody (HPAB-0088-FY) | FC | Human IgG1 |
| MRO-1733-CN | Rabbit Anti-PROM1 Polyclonal Antibody (MRO-1733-CN) | WB, IF, IHC, FC | Rabbit IgG |
| HPAB-1396-FY | Human Anti-PROM1 Recombinant Antibody (clone H133) | FC | Humanized IgG |
| VS3-QX919 | Mouse Anti-PROM1 Recombinant Antibody (clone 8F2-H6-D6) | WB | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0183-YC-S(P) | Human Anti-PROM1 Recombinant Antibody (clone h133H/h133La); scFv Fragment | ELISA, FC | Humanized scFv |
| HPAB-0088-FY-S(P) | Human Anti-PROM1 Recombinant Antibody; scFv Fragment (HPAB-0088-FY-S(P)) | FC | Human scFv |
| HPAB-1396-FY-F(E) | Human Anti-PROM1 Recombinant Antibody (clone H133); scFv Fragment | FC | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0183-YC-F(E) | Human Anti-PROM1 Recombinant Antibody (clone h133H/h133La); Fab Fragment | ELISA, FC | Humanized Fab |
| HPAB-0088-FY-F(E) | Human Anti-PROM1 Recombinant Antibody; Fab Fragment (HPAB-0088-FY-F(E)) | FC | Human Fab |
| HPAB-1396-FY-S(P) | Human Anti-PROM1 Recombinant Antibody (clone H133); Fab Fragment | FC | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-019CN | Mouse Anti-PROM1 Recombinant Antibody (NS-019CN) | ELISA, IF, IHC, FC | Mouse IgG |
| NS-019CN-F(E) | Mouse Anti-PROM1 Recombinant Antibody; Fab Fragment (NS-019CN-F(E)) | ELISA, IF, IHC, FC | Mouse Fab |
| NS-019CN-S(P) | Mouse Anti-PROM1 Recombinant Antibody; scFv Fragment (NS-019CN-S(P)) | ELISA, IF, IHC, FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN1161 | PE-A*02:01/Human PROM1 (YLQWIEFSI) MHC Tetramer | FCM, IHC | |
| MHC-CN1162 | APC-A*02:01/Human PROM1 (YLQWIEFSI) MHC Tetramer | FCM, IHC | |
| MHC-CN1163 | FITC-A*02:01/Human PROM1 (YLQWIEFSI) MHC Tetramer | FCM, IHC | |
| MHC-CN1164 | A*02:01/Human PROM1 (YLQWIEFSI) MHC Tetramer | FCM, IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0060-FY | Rabbit Anti-PROM1 Recombinant Antibody (clone AFY0031) | IF, IHC-P, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0924-YC86 | Mouse Anti-PROM1 Recombinant Antibody (VS-0924-YC86) - Cancer Stem Cell Marker | IHC, WB | Mouse IgG1 |
| VS-0924-YC87 | Rabbit Anti-PROM1 Antibody (VS-0924-YC87) - Cancer Stem Cell Marker | IHC, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY181 | CytoStream™ Mouse Anti-PROM1 Recombinant Antibody (clone 293C3) | FC | Mouse IgG2b, kappa |
| VS-0225-XY182 | CytoStream™ Mouse Anti-PROM1 Recombinant Antibody (VS-0225-XY182) | FC | Mouse IgG1, kappa |
| VS13-YC944 | CytoStream™ Mouse Anti-PROM1 Recombinant Antibody (VS13-YC944) | WB, IHC-P, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY5735 | Anti-PROM1 Immunohistochemistry Kit | IHC |
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