Recombinant Anti-human PROM1 Intrabody [(D-Arg)9]
CAT#: IAB-B028(A)
Recombinant anti-PROM1 intrabody linked to (D-Arg)9 works within cells to bind to cancer stem cell (CSC) marker PROM1 (CD133), expressed in 293T cells.
Gene Expression
Normal Tissue
Figure 1 Colon
Goblet cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4922/15212_A_8_3.jpg
Normal Tissue
Figure 2 Liver
Cholangiocytes
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4922/15212_A_7_4.jpg
Normal Tissue
Figure 3 Pancreas
Exocrine glandular cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4922/15212_A_2_3.jpg
Normal Tissue
Figure 4 Kidney
Bowman's capsule
Staining:High
Intensity: Strong
Quantity:>75%
Distal tubules
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Proximal tubules (cell body)
Staining:Medium
Intensity: Strong
Quantity: <25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4922/15212_A_8_5.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (AF22, CACO-2, CAPAN-2, EFO-21, NTERA-2, RPTEC TERT1)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000007062-PROM1
❮
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Specifications
- Immunogen
- human prominin 1
- Host Species
- human
- Type
- scFv-(D-Arg)9
- Cell Penetrating Peptide
- (D-Arg)9
It has been proven that polyarginine peptides composed of nine arginine amino acids (Arg-9) are able to translocate across cells very efficiently. This raises the question if molecular dynamics simulations would show a similar pathway for this highly hydrophilic and charged peptide as predicted for the Tat peptide. The simplicity of Arg-9 over other CPPs also helps isolate the role of the Arg sidechain on the translocation without the effect of other sidechains. Therefore, in this work we study computationally the translocation of Arg-9 through a lipid bilayer and show that the translocation mechanism is the same as for the Tat peptide.
- Species Reactivity
- human
- Applications
- Products can be used for: Enzyme-linked Immunosorbent Assay; Neutralization; Functional studies
Product Property
- Purity
- >95%, by SDS-PAGE with Coomassie Brilliant Blue staining
- Storage
- ≤1 year at -20°C.
Target
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "PROM1"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1990z | Mouse Anti-PROM1 Recombinant Antibody (clone 41D7) | WB, FC, IHC | Mouse IgG1 |
| HPAB-0183-YC | Human Anti-PROM1 Recombinant Antibody (clone h133H/h133La) | ELISA, FC | Humanized IgG |
| MRO-0275-CN | Recombinant Mouse Anti-PROM1 Monoclonal Antibody (D2-B1) | IHC, IF | Mouse IgG1 |
| VS7-0425-WR693 | Mouse Anti-PROM1 Recombinant Antibody (clone 2F8C5) | FC | Mouse IgG1 |
| VS7-0425-WR694 | Mouse Anti-PROM1 Monoclonal Antibody (VS7-0425-WR694) | IHC-P, IF, FC, ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B028(G) | Recombinant Anti-human PROM1 Intrabody [+36 GFP] | PCA, WB, FuncS | scFv-(+36GFP) |
| IAB-B028(T) | Recombinant Anti-human PROM1 Intrabody [Tat] | FACS, ELISA, IF, FuncS | scFv-Tat |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G057S | Anti-PROM1 immunotoxin (scFv)-Sap | Cytotoxicity assay, Function study |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1074CL | Anti-Human PROM1 Recombinant Antibody (AC133) | ELISA, ICC, IB | |
| TAB-1075CL | Mouse Anti-PROM1 Recombinant Antibody (TAB-1075CL) | WB, IF, FC, IHC | Mouse IgG |
| TAB-1074CL-S(P) | Anti-Human PROM1 Recombinant Antibody scFv Fragment (AC133) | ELISA | |
| TAB-1075CL-S(P) | Mouse Anti-PROM1 Recombinant Antibody; scFv Fragment (TAB-1075CL-S(P)) | WB, IF, FC | Mouse scFv |
| TAB-0375CL-F(E) | Anti-Mouse PROM1 Recombinant Antibody Fab Fragment (293AC1C3H9) | FC | Chimeric (mouse/human) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0183-YC-S(P) | Human Anti-PROM1 Recombinant Antibody (clone h133H/h133La); scFv Fragment | ELISA, FC | Humanized scFv |
| HPAB-0088-FY-S(P) | Human Anti-PROM1 Recombinant Antibody; scFv Fragment (HPAB-0088-FY-S(P)) | FC | Human scFv |
| HPAB-1396-FY-F(E) | Human Anti-PROM1 Recombinant Antibody (clone H133); scFv Fragment | FC | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0183-YC-F(E) | Human Anti-PROM1 Recombinant Antibody (clone h133H/h133La); Fab Fragment | ELISA, FC | Humanized Fab |
| HPAB-0088-FY-F(E) | Human Anti-PROM1 Recombinant Antibody; Fab Fragment (HPAB-0088-FY-F(E)) | FC | Human Fab |
| HPAB-1396-FY-S(P) | Human Anti-PROM1 Recombinant Antibody (clone H133); Fab Fragment | FC | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-019CN | Mouse Anti-PROM1 Recombinant Antibody (NS-019CN) | ELISA, IF, IHC, FC | Mouse IgG |
| NS-019CN-F(E) | Mouse Anti-PROM1 Recombinant Antibody; Fab Fragment (NS-019CN-F(E)) | ELISA, IF, IHC, FC | Mouse Fab |
| NS-019CN-S(P) | Mouse Anti-PROM1 Recombinant Antibody; scFv Fragment (NS-019CN-S(P)) | ELISA, IF, IHC, FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN1161 | PE-A*02:01/Human PROM1 (YLQWIEFSI) MHC Tetramer | FCM, IHC | |
| MHC-CN1162 | APC-A*02:01/Human PROM1 (YLQWIEFSI) MHC Tetramer | FCM, IHC | |
| MHC-CN1163 | FITC-A*02:01/Human PROM1 (YLQWIEFSI) MHC Tetramer | FCM, IHC | |
| MHC-CN1164 | A*02:01/Human PROM1 (YLQWIEFSI) MHC Tetramer | FCM, IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0060-FY | Rabbit Anti-PROM1 Recombinant Antibody (clone AFY0031) | IF, IHC-P, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0924-YC86 | Mouse Anti-PROM1 Recombinant Antibody (VS-0924-YC86) - Cancer Stem Cell Marker | IHC, WB | Mouse IgG1 |
| VS-0924-YC87 | Rabbit Anti-PROM1 Antibody (VS-0924-YC87) - Cancer Stem Cell Marker | IHC, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY181 | CytoStream™ Mouse Anti-PROM1 Recombinant Antibody (clone 293C3) | FC | Mouse IgG2b, kappa |
| VS-0225-XY182 | CytoStream™ Mouse Anti-PROM1 Recombinant Antibody (VS-0225-XY182) | FC | Mouse IgG1, kappa |
| VS13-YC944 | CytoStream™ Mouse Anti-PROM1 Recombinant Antibody (VS13-YC944) | WB, IHC-P, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC266 | Recombinant Anti-PROM1 Vesicular Antibody, EV Displayed (VS-0425-YC266) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY5735 | Anti-PROM1 Immunohistochemistry Kit | IHC |
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