Recombinant Anti-SCN9A Vesicular Antibody, EV Displayed (VS-0425-YC655) (CAT#: VS-0425-YC655)

• Application
• ELISA, FC, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• SCN9A

• Host Animal
• Rabbit

• Antibody Isotype
• IgG

• Species Reactivity
• Human

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• Protein A

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• Sodium voltage-gated channel alpha subunit 9

• Biological Process
• Ion transport, Sodium transport, Transport

• Molecular Function
• Ion channel, Sodium channel, Voltage-gated channel

• Cellular Localization
• Plasma membrane, Actin filaments, Focal adhesion sites

• Introduction
• This gene encodes a voltage-gated sodium channel which plays a significant role in nociception signaling. Mutations in this gene have been associated with primary erythermalgia, channelopathy-associated insensitivity to pain, and paroxysmal extreme pain disorder. [provided by RefSeq, Aug 2009]

• Alternative Names
• ETHA, Nav1.7, NE-NA, NENA, PN1

• Gene ID
• 6335

• UniProt ID
• Q15858

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