Recombinant Anti-SCN9A Vesicular Antibody, EV Displayed (VS-0425-YC655)
CAT#: VS-0425-YC655
The Recombinant Anti-SCN9A Vesicular Antibody, EV Displayed (VS-0425-YC655) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to SCN9A-expressed cells or tissues. SCN9A is a voltage-gated sodium channel significant in pain signaling, with mutations linked to conditions such as primary erythermalgia and paroxysmal extreme pain disorder.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line BJ
Immunofluorescent staining of human cell line BJ shows localization to plasma membrane, actin filaments & focal adhesion sites.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/61843/1332_D6_5_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IHC staining of human colon
Immunohistochemical staining of human colon shows cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13679/30465_A_7_3_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Glial cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous
Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13679/30465_B_7_5.jpg
Normal Tissue
Figure 4 Colon
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13679/30465_A_7_3.jpg
Normal Tissue
Figure 5 Liver
Cholangiocytes
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Hepatocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13679/30465_A_9_4.jpg
Normal Tissue
Figure 6 Kidney
Cells in glomeruli
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous
Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13679/30465_A_8_5.jpg
Normal Tissue
Figure 7 Testis
Cells in seminiferous ducts
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13679/30465_A_6_6.jpg
Normal Tissue
Figure 8 Lymph node
Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13679/30465_A_7_8.jpg
RNA Expression
Figure 9 RNA cell line category: Cell line enhanced (BJ, BJ hTERT+, HHSteC, hTERT-RPE1)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000169432-SCN9A/subcellular
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- SCN9A
- Host Animal
- Rabbit
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Sodium voltage-gated channel alpha subunit 9
- Biological Process
- Ion transport, Sodium transport, Transport
- Molecular Function
- Ion channel, Sodium channel, Voltage-gated channel
- Cellular Localization
- Plasma membrane, Actin filaments, Focal adhesion sites
- Introduction
- This gene encodes a voltage-gated sodium channel which plays a significant role in nociception signaling. Mutations in this gene have been associated with primary erythermalgia, channelopathy-associated insensitivity to pain, and paroxysmal extreme pain disorder. [provided by RefSeq, Aug 2009]
- Alternative Names
- ETHA, Nav1.7, NE-NA, NENA, PN1
- Gene ID
- 6335
- UniProt ID
- Q15858
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS-0425-YC655. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "SCN9A"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-891-F(E) | Recombinant Anti-human SCN9A Antibody Fab Fragment | ELISA, RIA, FuncS | Fab |
| MHH-891-F(E) | Recombinant Human Anti-human SCN9A Antibody Fab Fragment | WB, ELISA, FuncS | Fab |
| HPAB-0109-WJ-F(E) | Human Anti-SCN9A Recombinant Antibody (HPAB-0109-WJ-F(E)); Fab Fragment | ELISA | Human Fab |
| HPAB-0542-FY-F(E) | Human Anti-SCN9A Recombinant Antibody (clone 22D04); Fab Fragment | ELISA | Human Fab |
| HPAB-0543-FY-F(E) | Human Anti-SCN9A Recombinant Antibody (clone 28608); Fab Fragment | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-891-S(P) | Recombinant Anti-human SCN9A Antibody scFv Fragment | ELISA, IP, FuncS | scFv |
| MHH-891-S(P) | Recombinant Human Anti-human SCN9A Antibody scFv Fragment | WB, IHC, FuncS | scFv |
| HPAB-0052-FY-S(P) | Rabbit Anti-SCN9A Recombinant Antibody; scFv Fragment (HPAB-0052-FY-S(P)) | ELISA | Rabbit scFv |
| HPAB-0109-WJ-S(P) | Human Anti-SCN9A Recombinant Antibody (HPAB-0109-WJ-S(P)); scFv Fragment | ELISA | Human scFv |
| HPAB-0542-FY-S(P) | Human Anti-SCN9A Recombinant Antibody (clone 22D04); scFv Fragment | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-891 | Recombinant Human Anti-human SCN9A Antibody | WB, Neut, FuncS | IgG |
| MRO-1062-CN | Recombinant Mouse Anti-SCN9A Monoclonal Antibody (1D6) | IHC, IF, FC, WB | Mouse IgG2b |
| MRO-2056-CN | Rabbit Anti-SCN9A Polyclonal Antibody (MRO-2056-CN) | IF, IHC, FC | Rabbit IgG |
| MRO-2057-CN | Rabbit Anti-SCN9A Polyclonal Antibody (MRO-2057-CN) | IF, IHC | Rabbit IgG |
| HPAB-0542-FY | Human Anti-SCN9A Recombinant Antibody (clone 22D04) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0334CL | Human Anti-SCN9A Recombinant Antibody (TAB-0334CL) | FuncS, IHC, Block, Inhib, ELISA | Human IgG |
| TAB-0334CL-F(E) | Human Anti-SCN9A Recombinant Antibody; Fab Fragment (TAB-0334CL-F(E)) | FuncS, IHC, Block, Inhib, ELISA | Human Fab |
| TAB-474MZ | Human Anti-SCN9A Recombinant Antibody (TAB-474MZ) | ELISA | Human IgG |
| TAB-474MZ-S(P) | Human Anti-SCN9A Recombinant Antibody; scFv Fragment (TAB-474MZ-S(P)) | ELISA | Human scFv |
| TAB-475MZ-S(P) | Human Anti-SCN9A Recombinant Antibody; scFv Fragment (TAB-475MZ-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-469MZ-S(P) | Anti-Human SCN9A Recombinant Antibody scFv Fragment (8A7) | ELISA, FuncS | |
| TAB-470MZ-S(P) | Anti-Human SCN9A Recombinant Antibody scFv Fragment (8B6) | ELISA, FuncS | |
| TAB-471MZ-S(P) | Anti-Human SCN9A Recombinant Antibody scFv Fragment (9A1) | ELISA, FuncS | |
| TAB-472MZ-S(P) | Anti-Human SCN9A Recombinant Antibody scFv Fragment (9A6) | ELISA, FuncS | |
| TAB-473MZ-S(P) | Anti-Human SCN9A Recombinant Antibody scFv Fragment (9A11) | ELISA, FuncS |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-053CN | Mouse Anti-SCN9A Recombinant Antibody (NS-053CN) | ELISA, Block, FuncS | Mouse IgG1 |
| NS-053CN-F(E) | Mouse Anti-SCN9A Recombinant Antibody; Fab Fragment (NS-053CN-F(E)) | ELISA | Mouse Fab |
| NS-053CN-S(P) | Mouse Anti-SCN9A Recombinant Antibody; scFv Fragment (NS-053CN-S(P)) | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY6390 | Anti-SCN9A Immunohistochemistry Kit | IHC |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: WB, IF, IP, Neut, FuncS, ELISA, FC
Application: Neut, ELISA, IF, IP, FuncS, FC, IHC
Application: ELISA, Neut, IF, IP, FC, FuncS
Application: Neut, ELISA, IF, IP, FuncS, FC, WB
Application: FC, IP, ELISA, Neut, FuncS, IF, ICC
Application: ELISA, SPR, Inhib, FuncS
Application: ELISA, IHC, FC, IP, IF, BL
Application: ELISA, IHC, FC, IP, IF, FuncS
-2.png)
Application: WB, ELISA, FuncS
Application: ELISA, Vaccine, FuncS
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
