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SCN9A
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- Human Anti-SCN9A Recombinant Antibody (clone 22D04) (HPAB-0542-FY)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
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- Human Anti-SCN9A Recombinant Antibody (clone 28608) (HPAB-0543-FY)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
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- Recombinant Mouse Anti-SCN9A Monoclonal Antibody (1D6) (MRO-1062-CN)
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- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: IHC, IF, FC, WB
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- Rabbit Anti-SCN9A Polyclonal Antibody (MRO-2056-CN) (MRO-2056-CN)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IF, IHC, FC
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- Rabbit Anti-SCN9A Polyclonal Antibody (MRO-2057-CN) (MRO-2057-CN)
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- Species Reactivity: Human, Rat
- Type: Rabbit IgG
- Application: IF, IHC
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- Human Anti-SCN9A Recombinant Antibody (HPAB-0109-WJ) (HPAB-0109-WJ)
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- Species Reactivity: Human
- Type: Human IgG4, κ
- Application: ELISA
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- Rabbit Anti-SCN9A Recombinant Antibody (HPAB-0052-FY) (HPAB-0052-FY)
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- Species Reactivity: Human
- Type: Rabbit IgG1
- Application: ELISA
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- Recombinant Anti-human SCN9A Antibody (MOB-891)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: WB, FC, FuncS
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- Human Anti-SCN9A Recombinant Antibody; Fab Fragment (TAB-474MZ-F(E)) (TAB-474MZ-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
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- Human Anti-SCN9A Recombinant Antibody; Fab Fragment (TAB-475MZ-F(E)) (TAB-475MZ-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
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- Anti-Human SCN9A Recombinant Antibody, Humanized (TAB-551CL)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Antibody
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- Human Anti-SCN9A Recombinant Antibody (TAB-0334CL) (TAB-0334CL)
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- Species Reactivity: No Cross-reactivity with Nav1.5
- Type: Human IgG
- Application: FuncS, IHC, Block, Inhib, ELISA
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- Human Anti-SCN9A Recombinant Antibody; scFv Fragment (TAB-0334CL-S(P)) (TAB-0334CL-S(P))
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- Species Reactivity: No Cross-reactivity with Nav1.5
- Type: Human scFv
- Application: FuncS, IHC, Block, Inhib, ELISA
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- Human Anti-SCN9A Recombinant Antibody; Fab Fragment (TAB-0334CL-F(E)) (TAB-0334CL-F(E))
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- Species Reactivity: No Cross-reactivity with Nav1.5
- Type: Human Fab
- Application: FuncS, IHC, Block, Inhib, ELISA
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- Anti-Human SCN9A Recombinant Antibody (8A7) (TAB-469MZ)
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- Derivation: Library
- Application: ELISA, FuncS
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- Mouse Anti-SCN9A Recombinant Antibody; Fab Fragment (TAB-476MZ-F(E)) (TAB-476MZ-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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- Recombinant Anti-human SCN9A Antibody Fab Fragment (MOB-891-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: ELISA, RIA, FuncS
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- Recombinant Anti-human SCN9A Antibody scFv Fragment (MOB-891-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, IP, FuncS
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- Rabbit Anti-SCN9A Recombinant Antibody; scFv Fragment (HPAB-0052-FY-S(P)) (HPAB-0052-FY-S(P))
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- Species Reactivity: Human
- Type: Rabbit scFv
- Application: ELISA
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- Rabbit Anti-SCN9A Recombinant Antibody; Fab Fragment (HPAB-0052-FY-F(E)) (HPAB-0052-FY-F(E))
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- Species Reactivity: Human
- Type: Rabbit Fab
- Application: ELISA
Compare
- Anti-Human SCN9A Recombinant Antibody Fab Fragment (9A6) (TAB-472MZ-F(E))
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- Derivation: Library
- Application: ELISA, FuncS
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- Anti-Human SCN9A Recombinant Antibody Fab Fragment (9A11) (TAB-473MZ-F(E))
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- Derivation: Library
- Application: ELISA, FuncS
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- Anti-Human SCN9A Recombinant Antibody Fab Fragment (8A7) (TAB-469MZ-F(E))
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- Derivation: Library
- Application: ELISA, FuncS
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- Anti-Human SCN9A Recombinant Antibody Fab Fragment (8B6) (TAB-470MZ-F(E))
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- Derivation: Library
- Application: ELISA, FuncS
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- Anti-Human SCN9A Recombinant Antibody Fab Fragment (9A1) (TAB-471MZ-F(E))
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- Derivation: Library
- Application: ELISA, FuncS
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- Anti-Human SCN9A Recombinant Antibody scFv Fragment (8A7) (TAB-469MZ-S(P))
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- Derivation: Library
- Application: ELISA, FuncS
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- Anti-Human SCN9A Recombinant Antibody scFv Fragment (8B6) (TAB-470MZ-S(P))
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- Derivation: Library
- Application: ELISA, FuncS
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- Anti-Human SCN9A Recombinant Antibody scFv Fragment (9A1) (TAB-471MZ-S(P))
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- Derivation: Library
- Application: ELISA, FuncS
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- Anti-Human SCN9A Recombinant Antibody scFv Fragment (9A6) (TAB-472MZ-S(P))
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- Derivation: Library
- Application: ELISA, FuncS
Compare
- Anti-Human SCN9A Recombinant Antibody scFv Fragment (9A11) (TAB-473MZ-S(P))
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- Derivation: Library
- Application: ELISA, FuncS
Compare
- Anti-Human SCN9A Recombinant Antibody (8B6) (TAB-470MZ)
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- Derivation: Library
- Application: ELISA
Compare
- Anti-Human SCN9A Recombinant Antibody (9A1) (TAB-471MZ)
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- Derivation: Library
- Application: ELISA
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- Anti-Human SCN9A Recombinant Antibody (9A6) (TAB-472MZ)
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- Derivation: Library
- Application: ELISA
Compare
- Anti-Human SCN9A Recombinant Antibody (9A11) (TAB-473MZ)
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- Derivation: Library
- Application: ELISA
Compare
- Human Anti-SCN9A Recombinant Antibody (HPAB-0109-WJ-S(P)); scFv Fragment (HPAB-0109-WJ-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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- Human Anti-SCN9A Recombinant Antibody (HPAB-0109-WJ-F(E)); Fab Fragment (HPAB-0109-WJ-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
Compare
- Human Anti-SCN9A Recombinant Antibody (clone 22D04); scFv Fragment (HPAB-0542-FY-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
Compare
- Human Anti-SCN9A Recombinant Antibody (clone 28608); scFv Fragment (HPAB-0543-FY-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
Compare
- Human Anti-SCN9A Recombinant Antibody (clone 22D04); Fab Fragment (HPAB-0542-FY-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
Compare
- Human Anti-SCN9A Recombinant Antibody (clone 28608); Fab Fragment (HPAB-0543-FY-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
Compare
- Recombinant Human Anti-human SCN9A Antibody Fab Fragment (MHH-891-F(E))
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- Derivation: Human
- Species Reactivity: Human
- Type: Fab
- Application: WB, ELISA, FuncS
Compare
- Recombinant Human Anti-human SCN9A Antibody scFv Fragment (MHH-891-S(P))
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- Derivation: Human
- Species Reactivity: Human
- Type: scFv
- Application: WB, IHC, FuncS
Compare
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- Species Reactivity: Human
- Target: SCN9A
- Host Animal: Rabbit
- Application: ELISA, FC, Cell-uptake
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- Anti-SCN9A Immunohistochemistry Kit (VS-0525-XY6390)
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- Species Reactivity: Human
- Target: SCN9A
- Application: IHC
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For Research Use Only. Not For Clinical Use.
This gene encodes a voltage-gated sodium channel which plays a significant role in nociception signaling. Mutations in this gene have been associated with primary erythermalgia, channelopathy-associated insensitivity to pain, and paroxysmal extreme pain disorder. [provided by RefSeq, Aug 2009]
Protein class
Disease related genes, FDA approved drug targets, Human disease related genes, Transporters, Voltage-gated ion channels
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Oligodendrocyte precursor cells, Hofbauer cells, Inhibitory neurons, dendritic cells, Langerhans cells)
Immune cell specificity
Immune cell enriched (plasmacytoid DC)
Cell line specificity
Cell line enhanced (BJ, BJ hTERT+, HHSteC, hTERT-RPE1)
Interaction
The sodium channel complex consists of a large, channel-forming alpha subunit (SCN9A) regulated by one or more beta subunits (SCN1B, SCN2B, SCN3B and SCN4B) (PubMed:7720699, 17167479, 25240195). SCN1B and SCN3B are non-covalently associated with SCN2A. SCN2B and SCN4B are disulfide-linked to SCN2A. Interacts with NEDD4 and NEDD4L (By similarity). Interacts with the scorpion alpha-toxin CvIV4 (PubMed:21887265). Interacts with the conotoxin GVIIJ (PubMed:24497506). Interacts with the spider huwentoxin-IV (through the extracellular loop S3-S4 of repeat II) (PubMed:20855463, 21659528, 30661758, 30765606). Interacts with the spider protoxin-II (through the extracellular loop S3-S4 of repeats II and IV) (PubMed:20855463, 21659528, 30661758, 30765606). Interacts with the spider beta/delta-theraphotoxin-Pre1a (PubMed:28428547).
Molecular function
Ion channel, Sodium channel, Voltage-gated channel
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