Recombinant Anti-SIGLEC9 Vesicular Antibody, EV Displayed (VS-0425-YC471)
CAT#: VS-0425-YC471
The Recombinant Anti-SIGLEC9 Vesicular Antibody, EV Displayed (VS-0425-YC471) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to SIGLEC9-expressed cells or tissues. The SIGLEC9 is involved in cell adhesion and immune regulation, active in the plasma membrane.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human spleen
Immunohistochemical staining of human spleen shows strong cytoplasmic positivity in cells in red pulp.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10682/26903_B_8_4_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10682/26903_B_7_5.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10682/26903_A_9_3.jpg
Normal Tissue
Figure 4 Liver
Cholangiocytes Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10682/26903_A_8_4.jpg
Normal Tissue
Figure 5 Testis
Cells in seminiferous ducts Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous nuclear Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10682/26903_A_6_6.jpg
Normal Tissue
Figure 6 Spleen
Cells in red pulp Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10682/26903_B_8_4.jpg
RNA Expression
Figure 7 RNA cell line category: Group enriched (Karpas-707, RPMI-8226)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000129450-SIGLEC9
❮
❯
Recombinant Antibody
- Application
- Cyt, ELISA, FC, Neut, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- SIGLEC9
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Sialic acid binding Ig like lectin 9
- Biological Process
- Cell adhesion
- Introduction
- Predicted to enable monosaccharide binding activity and sialic acid binding activity. Predicted to be involved in cell adhesion. Predicted to act upstream of or within negative regulation of inflammatory response and negative regulation of phagocytosis, engulfment. Predicted to be located in external side of plasma membrane. Predicted to be active in plasma membrane.
- Alternative Names
- CD329
- Gene ID
- 27180
- UniProt ID
- Q9Y336
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Datasheet
MSDS
COA
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See other products for "SIGLEC9"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1963CQ | Recombinant Mouse Anti-SIGLEC9 Antibody (CBL273) | FC, ELISA, WB, Neut | IgG2a |
| NEUT-1964CQ | Recombinant Mouse Anti-SIGLEC9 Antibody (MM0552-6K12) | WB, Neut | IgG2 |
| NEUT-1965CQ | Recombinant Mouse Anti-SIGLEC9 Antibody (CBL164) | Neut, WB | IgG2 |
| NEUT-1966CQ | Recombinant Mouse Anti-SIGLEC9 Antibody (CBL711) | WB, FC, CyTOF, ELISA(Cap), Neut | IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0648-YC | Mouse Anti-SIGLEC9 Recombinant Antibody (HPAB-M0648-YC) | FC, Cyt, Neut | Mouse IgG |
| HPAB-M0649-YC | Mouse Anti-SIGLEC9 Recombinant Antibody (HPAB-M0649-YC) | FC, Cyt, Neut | Mouse IgG |
| HPAB-M0650-YC | Mouse Anti-SIGLEC9 Recombinant Antibody (HPAB-M0650-YC) | FC, Cyt, Neut | Mouse IgG |
| HPAB-M0651-YC | Mouse Anti-SIGLEC9 Recombinant Antibody (HPAB-M0651-YC) | FC, Cyt | Mouse IgG |
| HPAB-3335LY | Human Anti-SIGLEC9 Recombinant Antibody (HPAB-3335LY) | FC | Humanized IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0648-YC-S(P) | Mouse Anti-SIGLEC9 Recombinant Antibody; scFv Fragment (HPAB-M0648-YC-S(P)) | FC, Cyt, Neut | Mouse scFv |
| HPAB-M0649-YC-S(P) | Mouse Anti-SIGLEC9 Recombinant Antibody; scFv Fragment (HPAB-M0649-YC-S(P)) | FC, Cyt, Neut | Mouse scFv |
| HPAB-M0650-YC-S(P) | Mouse Anti-SIGLEC9 Recombinant Antibody; scFv Fragment (HPAB-M0650-YC-S(P)) | FC, Cyt, Neut | Mouse scFv |
| HPAB-M0651-YC-S(P) | Mouse Anti-SIGLEC9 Recombinant Antibody; scFv Fragment (HPAB-M0651-YC-S(P)) | FC, Cyt | Mouse scFv |
| HPAB-3335LY-S(P) | Human Anti-SIGLEC9 Recombinant Antibody; scFv Fragment (HPAB-3335LY-S(P)) | FC | Humanized scfv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0648-YC-F(E) | Mouse Anti-SIGLEC9 Recombinant Antibody; Fab Fragment (HPAB-M0648-YC-F(E)) | FC, Cyt, Neut | Mouse Fab |
| HPAB-M0649-YC-F(E) | Mouse Anti-SIGLEC9 Recombinant Antibody; Fab Fragment (HPAB-M0649-YC-F(E)) | FC, Cyt, Neut | Mouse Fab |
| HPAB-M0650-YC-F(E) | Mouse Anti-SIGLEC9 Recombinant Antibody; Fab Fragment (HPAB-M0650-YC-F(E)) | FC, Cyt, Neut | Mouse Fab |
| HPAB-M0651-YC-F(E) | Mouse Anti-SIGLEC9 Recombinant Antibody; Fab Fragment (HPAB-M0651-YC-F(E)) | FC, Cyt | Mouse Fab |
| HPAB-3335LY-F(E) | Human Anti-SIGLEC9 Recombinant Antibody; Fab Fragment (HPAB-3335LY-F(E)) | FC | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY479 | Mouse Anti-NHP SIGLEC9 Recombinant Antibody (clone OTI6D8) | WB, IHC, ICC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY6588 | Anti-SIGLEC9 Immunohistochemistry Kit | IHC | |
| VS-0525-XY6589 | Anti-Human SIGLEC9 Immunohistochemistry Kit | IHC |
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