Recombinant Rabbit Anti-SLC27A4 Antibody (clone 11A1) (CAT#: VS4-CJ115)

• Immunogen
• A synthesized peptide derived from human SLC27A4

• Host Species
• Rabbit

• Type
• Rabbit IgG

• Specificity
• Human, Mouse SLC27A4

• Species Reactivity
• Human, Mouse

• Clone
• 11A1

• Applications
• ELISA, WB

• Conjugate
• Unconjugated

• Purification
• Affinity chromatography

• Purity
• >95% as determined by SDS-PAGE

• Format
• Liquid

• Buffer
• 50% Glycerol, 150 mM NaCl, PBS, pH 7.4.

• Preservative
• 0.02% Sodium Azide

• Storage
• Store at -20°C or -80°C upon receipt. Avoid repeated freeze.

• Application Notes
• This antibody has been tested for use in ELISA, Western Blot (1:500-1:2000).

• Alternative Names
• IPS; FATP4; ACSVL4

• Gene ID
• 10999

• UniProt ID
• Q6P1M0

• Long Name
• Solute carrier family 27 member 4

• Sequence Similarities
• Belongs to the ATP-dependent AMP-binding enzyme family.

• Cellular Localization
• Endoplasmic reticulum, Membrane

• Protein Refseq
• NP_005085.2

• Function
• Mediates the levels of long-chain fatty acids (LCFA) in the cell by facilitating their transport across cell membranes (PubMed:10518211, PubMed:12556534, PubMed:20448275, PubMed:21395585, PubMed:22022213).
  Appears to be the principal fatty acid transporter in small intestinal enterocytes (PubMed:20448275).
  Also functions as an acyl-CoA ligase catalyzing the ATP-dependent formation of fatty acyl-CoA using LCFA and very-long-chain fatty acids (VLCFA) as substrates, which prevents fatty acid efflux from cells and might drive more fatty acid uptake (PubMed:22022213, PubMed:24269233).
  Plays a role in the formation of the epidermal barrier. Required for fat absorption in early embryogenesis (By similarity).
  Probably involved in fatty acid transport across the blood barrier (PubMed:21395585).
  Indirectly inhibits RPE65 via substrate competition and via production of VLCFA derivatives like lignoceroyl-CoA. Prevents light-induced degeneration of rods and cones (By similarity).

Isotype Control

• MOB-208CQ
• Rabbit IgG Isotype Control Antibody

Secondary Antibody

• 2ND-059CQ
• Goat Anti-Rabbit IgG (H&L) Antibody

• 2ND-057CQ
• Donkey Anti-Rabbit IgG (H&L) Antibody

Recommended Dilution Buffer

• MRO-0253YJ
• Reconstitution Buffer PBS