Recombinant Rabbit Anti-SLC27A4 Antibody (clone 11A1)

CAT#: VS4-CJ115

This rabbit anti-SLC27A4 antibody (clone 11A1) is a product that recognizes human, mouse SLC27A4. The immunogen of this antibody is a synthesized peptide derived from human SLC27A4. The mAb has been tested for use in ELISA, Western Blot (1:500-1:2000).

Specifications

  • Immunogen
  • A synthesized peptide derived from human SLC27A4
  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human, Mouse SLC27A4
  • Species Reactivity
  • Human, Mouse
  • Clone
  • 11A1
  • Applications
  • ELISA, WB
  • Conjugate
  • Unconjugated

Product Property

  • Purification
  • Affinity chromatography
  • Purity
  • >95% as determined by SDS-PAGE
  • Format
  • Liquid
  • Buffer
  • 50% Glycerol, 150 mM NaCl, PBS, pH 7.4.
  • Preservative
  • 0.02% Sodium Azide
  • Storage
  • Store at -20°C or -80°C upon receipt. Avoid repeated freeze.

Applications

  • Application Notes
  • This antibody has been tested for use in ELISA, Western Blot (1:500-1:2000).

Target

  • Alternative Names
  • IPS; FATP4; ACSVL4
  • Long Name
  • Solute carrier family 27 member 4
  • Sequence Similarities
  • Belongs to the ATP-dependent AMP-binding enzyme family.
  • Cellular Localization
  • Endoplasmic reticulum, Membrane
  • Function
  • Mediates the levels of long-chain fatty acids (LCFA) in the cell by facilitating their transport across cell membranes (PubMed:10518211, PubMed:12556534, PubMed:20448275, PubMed:21395585, PubMed:22022213).
    Appears to be the principal fatty acid transporter in small intestinal enterocytes (PubMed:20448275).
    Also functions as an acyl-CoA ligase catalyzing the ATP-dependent formation of fatty acyl-CoA using LCFA and very-long-chain fatty acids (VLCFA) as substrates, which prevents fatty acid efflux from cells and might drive more fatty acid uptake (PubMed:22022213, PubMed:24269233).
    Plays a role in the formation of the epidermal barrier. Required for fat absorption in early embryogenesis (By similarity).
    Probably involved in fatty acid transport across the blood barrier (PubMed:21395585).
    Indirectly inhibits RPE65 via substrate competition and via production of VLCFA derivatives like lignoceroyl-CoA. Prevents light-induced degeneration of rods and cones (By similarity).
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

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COA

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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