Recombinant Anti-SLC30A10 Vesicular Antibody, EV Displayed (VS-0425-YC481)
CAT#: VS-0425-YC481
The Recombinant Anti-SLC30A10 Vesicular Antibody, EV Displayed (VS-0425-YC481) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to SLC30A10-expressed cells or tissues. The SLC30A10 is a transporter involved in manganese levels, with deficiencies linked to neurological disorders.
Gene Expression
Normal Tissue
Figure 1 Colon
Enterocytes - Microvilli Staining: High Intensity: Strong
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/64547/164744_A_7_3.jpg
Normal Tissue
Figure 2 High expression in liver
Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/64547/164744_A_7_4.jpg
RNA Expression
Figure 3 RNA cell line category: Cell line enhanced (HEK93, HEL, K-562)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000196660-SLC30A10
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- SLC30A10
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Solute carrier family 30 member 10
- Biological Process
- Antiport, Ion transport, Transport, Zinc transport
- Introduction
- This gene is highly expressed in the liver and is inducible by manganese. Its protein product appears to be critical in maintaining manganese levels, and has higher specificity for manganese than zinc. Loss of function mutations appear to result in a pleomorphic phenotype, including dystonia and adult-onset parkinsonism. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Mar 2012]
- Alternative Names
- DKFZp547M236, ZnT-10, ZNT8, ZRC1
- Gene ID
- 55532
- UniProt ID
- Q6XR72
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "SLC30A10"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1754z | Recombinant Anti-Human SLC30A10 Antibody | WB, IF, FuncS | IgG |
| HPAB-M0205-YC | Human Anti-SLC30A10 Recombinant Antibody (clone C22) | ELISA, WB, IHC | Humanized IgG |
| HPAB-M0206-YC | Human Anti-SLC30A10 Recombinant Antibody (clone C27) | ELISA, WB, IHC | Human IgG |
| CAT | Product Name | Application | Type |
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| MOB-1754z-F(E) | Recombinant Anti-Human SLC30A10 Antibody Fab Fragment | WB, Neut, FuncS | Fab |
| HPAB-M0205-YC-F(E) | Human Anti-SLC30A10 Recombinant Antibody (clone C22); Fab Fragment | ELISA, WB, IHC | Humanized Fab |
| HPAB-M0206-YC-F(E) | Human Anti-SLC30A10 Recombinant Antibody (clone C27); Fab Fragment | ELISA, WB, IHC | Human Fab |
| CAT | Product Name | Application | Type |
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| MOB-1754z-S(P) | Recombinant Anti-Human SLC30A10 Antibody scFv Fragment | IP, IF, Biosensors, FuncS | scFv |
| HPAB-M0205-YC-S(P) | Human Anti-SLC30A10 Recombinant Antibody (clone C22); scFv Fragment | ELISA, WB, IHC | Humanized scFv |
| HPAB-M0206-YC-S(P) | Human Anti-SLC30A10 Recombinant Antibody (clone C27); scFv Fragment | ELISA, WB, IHC | Human scFv |
| CAT | Product Name | Application | Type |
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| MOB-0280MC | Rabbit Anti-SLC30A10 Antibody | WB |
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