Recombinant Anti-SLC34A2 Vesicular Antibody, EV Displayed (VS-0425-YC70) (CAT#: VS-0425-YC70)
The Recombinant Anti-SLC34A2 Vesicular Antibody, EV Displayed (VS-0425-YC70) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to SLC34A2-expressed cells or tissues. The SLC34A2 is a sodium-dependent phosphate transporter implicated in pulmonary alveolar microlithiasis.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line RPTEC TERT1
(Immunofluorescent staining of human cell line RPTEC TERT1 shows localization to nucleoplasm, plasma membrane & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37989/1788_A4_7_cr5971b651a2dbe_selected.jpg
(Immunofluorescent staining of human cell line RPTEC TERT1 shows localization to nucleoplasm, plasma membrane & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37989/1788_A4_7_cr5971b651a2dbe_selected.jpg
Figure 2 IF staining of human cell line RPTEC TERT1
(Immunofluorescent staining of human cell line RPTEC TERT1 shows localization to plasma membrane & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/66474/1788_E8_17_cr5971fcb00a73f_selected.jpg
(Immunofluorescent staining of human cell line RPTEC TERT1 shows localization to plasma membrane & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/66474/1788_E8_17_cr5971fcb00a73f_selected.jpg
Figure 3 High expression in lung
(Alveolar cells type Alveolar cells type I I Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37989/141847_A_2_4.jpg
(Alveolar cells type Alveolar cells type I I Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37989/141847_A_2_4.jpg
Figure 4 RNA cell line category: Group enriched (BEWO, EFO-21, RPTEC TERT1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000157765-SLC34A2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000157765-SLC34A2
Recombinant Antibody
- Application
- ELISA, FC, Neut, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- SLC34A2
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Solute carrier family 34 member 2
- Biological Process
- Ion transport, Sodium transport, Symport, Transport
- Cellular Localization
- Plasma membrane, Nucleoplasm, Cytosol
- Introduction
- The protein encoded by this gene is a pH-sensitive sodium-dependent phosphate transporter. Phosphate uptake is increased at lower pH. Defects in this gene are a cause of pulmonary alveolar microlithiasis. Three transcript variants encoding two different isoforms have been found for this gene.
- Alternative Names
- NAPI-3B
- Gene ID
- 10568
- UniProt ID
- O95436
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1661z | Mouse Anti-SLC34A2 Recombinant Antibody (MOB-1661z) | ELISA, DB, WB, IHC, FC | Mouse IgG1 |
| HPAB-0341LY | Human Anti-SLC34A2 Recombinant Antibody (HPAB-0341LY) | ELISA, Block | Humanized IgG1 |
| HPAB-M0281-YC | Human Anti-SLC34A2 Recombinant Antibody (HPAB-M0281-YC) | FuncS | Human IgG1 |
| HPAB-N0246-YC | Human Anti-SLC34A2 Recombinant Antibody (HPAB-N0246-YC) | FuncS | Humanized IgG |
| MOB-096YJL | Rabbit Anti-SLC34A2 Recombinant Antibody (clone CBS133) | IHC-P, ICC, IF, FC | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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