Mouse Anti-SLC34A2 Recombinant Antibody (MOB-1661z)
CAT#: MOB-1661z
The purified Mouse Anti-SLC34A2 Recombinant Antibody (MOB-1661z) product displayed high specificity against the SLC34A2 protein of Human.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line RPTEC TERT1
Immunofluorescent staining of human cell line RPTEC TERT1 shows localization to nucleoplasm, plasma membrane & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/37989/1788_A4_7_cr5971b651a2dbe_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line RPTEC TERT1
Immunofluorescent staining of human cell line RPTEC TERT1 shows localization to plasma membrane & vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/66474/1788_E8_17_cr5971fcb00a73f_selected.jpg
Normal Tissue
Figure 3 High expression in lung
Alveolar cells type Alveolar cells type I I Staining: High Intensity: Strong Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/37989/141847_A_2_4.jpg
RNA Expression
Figure 4 RNA cell line category: Group enriched (BEWO, EFO-21, RPTEC TERT1)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000157765-SLC34A2
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Specifications
- Immunogen
- An isolated immunogenic human SLC34A2 polypeptide
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human SLC34A2
- Species Reactivity
- Human
- Applications
- ELISA, DB, WB, IHC, FC
- Conjugate
- Unconjugated
- Related Disease
- Pulmonary Alveolar Microlithiasis and Testicular Microlithiasis
Product Property
- Clonality
- Monoclonal Antibody
- Purification
- Affinity purified
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS, pH 7.4
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Cold Packs
Target
- Alternative Names
- SLC34A2; NPTIIb; Solute Carrier Family 34 (Type II Sodium/Phosphate Cotransporter), Member 2; Sodium-Phosphate Transport Protein 2B; Na(+)-Dependent Phosphate Cotransporter 2B; NAPI-3B; NaPi3b; Solute Carrier Family 34 Member 2; Sodium/Phosphate Cotranspo
- Gene ID
- 10568
- UniProt ID
- O95436
- Long Name
- Solute Carrier Family 34 Member 2
- Protein Refseq
- NP_006415.3
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Comprehensive Research Tool
This antibody is a comprehensive research tool that offers detailed insights into SLC34A2-related pathways. Its application across various assays makes it versatile, enhancing our capacity to analyze cancer cell metabolism intricately.
Versatile for Multiple Assays
The versatility of this antibody in DB, WB, and FC is unparalleled. It consistently provides reliable results, making it a staple in our lab as we explore various aspects of tumor biology.
Enhances Metastasis Research
In metastasis research, the antibody's ability to accurately profile SLC34A2 expression supports our study of how transport abnormalities contribute to cancer spread, offering potential intervention points.
Q&As
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What is the main application of the Anti-SLC34A2 Recombinant Antibody (MOB-1661z)?
A: This recombinant antibody is primarily used in cancer research to study the expression of SLC34A2, a sodium-dependent phosphate transporter linked with various cancers. Applications include ELISA, dot blotting (DB), Western blotting (WB), immunohistochemistry (IHC), and flow cytometry (FC) to understand its role in tumorigenesis and as a potential biomarker.
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What is the roles of SLC34A2 playing in Pulmonary Alveolar Microlithiasis (PAM)?
A: PAM is often genetic, linked to mutations in the SLC34A2 gene, which encodes a sodium-phosphate co-transporter important for phosphate homeostasis in the lungs. Mutations lead to impaired phosphate transport and accumulation of calcium phosphate.
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What insights does this antibody provide into the metastatic potential of cancer cells?
A: By studying the expression patterns of SLC34A2, the antibody helps identify changes associated with cell migration and invasion, offering clues about a tumor's propensity to metastasize and aiding in the development of anti-metastatic strategies.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "SLC34A2"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1661z-F(E) | Recombinant Anti-Human SLC34A2 Antibody Fab Fragment | IF, FC, FuncS | Fab |
| HPAB-0341LY-F(E) | Human Anti-SLC34A2 Recombinant Antibody; Fab Fragment (HPAB-0341LY-F(E)) | ELISA, Block | Humanized Fab |
| HPAB-M0659-YC-F(E) | Human Anti-SLC34A2 Recombinant Antibody; Fab Fragment (HPAB-M0659-YC-F(E)) | FC, IHC, FuncS | Humanized Fab |
| HPAB-N0246-YC-F(E) | Human Anti-SLC34A2 Recombinant Antibody; Fab Fragment (HPAB-N0246-YC-F(E)) | FuncS | Humanized Fab |
| HPAB-0544-FY-F(E) | Human Anti-SLC34A2 Recombinant Antibody; Fab Fragment (HPAB-0544-FY-F(E)) | RIA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-H45 | Human Anti-SLC34A2 Recombinant Antibody (TAB-H45) | ELISA, FC, IP, FuncS, IF, Neut, ICC | Human IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-467MZ | Mouse Anti-SLC34A2 Recombinant Antibody (TAB-467MZ) | FC, Inhib | Mouse IgG1 |
| TAB-467MZ-S(P) | Mouse Anti-SLC34A2 Recombinant Antibody; scFv Fragment (TAB-467MZ-S(P)) | SDS-PAGE, IHC, WB | Mouse scFv |
| TAB-467MZ-F(E) | Mouse Anti-SLC34A2 Recombinant Antibody; Fab Fragment (TAB-467MZ-F(E)) | SDS-PAGE, IHC, WB | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-468MZ | Human Anti-SLC34A2 Recombinant Antibody (TAB-468MZ) | FC, Inhib | Humanized antibody |
| TAB-468MZ-S(P) | Human Anti-SLC34A2 Recombinant Antibody; scFv Fragment (TAB-468MZ-S(P)) | SDS-PAGE, IHC, WB | Humanized scFv |
| TAB-468MZ-F(E) | Human Anti-SLC34A2 Recombinant Antibody; Fab Fragment (TAB-468MZ-F(E)) | SDS-PAGE, IHC, WB | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0341LY-S(P) | Human Anti-SLC34A2 Recombinant Antibody; scFv Fragment (HPAB-0341LY-S(P)) | ELISA, Block | Humanized scfv |
| HPAB-M0281-YC-S(P) | Human Anti-SLC34A2 Recombinant Antibody; scFv Fragment (HPAB-M0281-YC-S(P)) | FuncS | Human scFv |
| HPAB-M0282-YC-S(P) | Human Anti-SLC34A2 Recombinant Antibody; scFv Fragment (HPAB-M0282-YC-S(P)) | FC, FuncS | Human scFv |
| HPAB-N0246-YC-S(P) | Human Anti-SLC34A2 Recombinant Antibody; scFv Fragment (HPAB-N0246-YC-S(P)) | FuncS | Humanized scFv |
| HPAB-0544-FY-S(P) | Human Anti-SLC34A2 Recombinant Antibody; scFv Fragment (HPAB-0544-FY-S(P)) | RIA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0659-YC | Human Anti-SLC34A2 Recombinant Antibody (HPAB-M0659-YC) | FC, IHC, FuncS | Humanized IgG |
| HPAB-M0281-YC | Human Anti-SLC34A2 Recombinant Antibody (HPAB-M0281-YC) | FuncS | Human IgG1 |
| HPAB-M0282-YC | Human Anti-SLC34A2 Recombinant Antibody (HPAB-M0282-YC) | FC, FuncS | Human IgG1 |
| HPAB-0544-FY | Human Anti-SLC34A2 Recombinant Antibody (HPAB-0544-FY) | RIA | Human IgG |
| MOB-096YJL | Rabbit Anti-SLC34A2 Recombinant Antibody (clone CBS133) | IHC-P, ICC, IF, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-H45 | Afuco™ Anti-SLC34A2 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-H45) | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY167 | Human Anti-SLC34A2 scFv-Fc Chimera (VS-0425-FY167) | IHC | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC70 | Recombinant Anti-SLC34A2 Vesicular Antibody, EV Displayed (VS-0425-YC70) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY6677 | Anti-SLC34A2 Immunohistochemistry Kit | IHC |
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