Recombinant Anti-TACSTD2 Vesicular Antibody, EV Displayed (VS-0425-YC132) (CAT#: VS-0425-YC132)
The Recombinant Anti-TACSTD2 Vesicular Antibody, EV Displayed (VS-0425-YC132) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to TACSTD2-expressed cells or tissues. The TACSTD2 is a carcinoma-associated antigen acting as a cell surface receptor that transduces calcium signals, with mutations associated with gelatinous drop-like corneal dystrophy.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line MCF7
(Immunofluorescent staining of human cell line MCF7 shows localization to nucleoli & plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55067/if_selected.jpg
(Immunofluorescent staining of human cell line MCF7 shows localization to nucleoli & plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55067/if_selected.jpg
Figure 2 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55067/893_A3_7_blue_red_green.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55067/893_A3_7_blue_red_green.jpg
Figure 3 Urinary bladder
(Urothelial cells
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/43104/93730_A_6_5.jpg
(Urothelial cells
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/43104/93730_A_6_5.jpg
Figure 4 RNA cell line category: Cell line enhanced (A-431, CAPAN-2, HaCaT, RT4)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000184292-TACSTD2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000184292-TACSTD2
Figure 4 RNA cell line category: Cell line enhanced (A-431, CAPAN-2, HaCaT, RT4)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000184292-TACSTD2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000184292-TACSTD2
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- TACSTD2
- Host Animal
- Human
- Antibody Isotype
- IgG1 kappa
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Tumor associated calcium signal transducer 2
- Biological Process
- Sensory transduction, Vision
- Molecular Function
- Tumor antigen
- Cellular Localization
- Plasma membrane, Nucleoli, Vesicles
- Introduction
- This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.
- Alternative Names
- EGP-1, GA733-1, M1S1, TROP2
- Gene ID
- 4070
- UniProt ID
- P09758
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1222z | Mouse Anti-TACSTD2 Recombinant Antibody (clone 22B1) | WB, IP, IF, IHC, ELISA | Mouse IgG1, κ |
| MOB-1932CT | Recombinant Mouse anti-Human TACSTD2 Monoclonal antibody (273-57.3) | ICC/IF, IHC-P | |
| HPAB-0303CQ | Mouse Anti-TACSTD2 Recombinant Antibody (clone AR47A6.4.2 (AR002)) | ELISA, Inhib | Mouse IgG2a, κ |
| HPAB-0304CQ | Human Anti-TACSTD2 Recombinant Antibody (clone huAR47A6.4.2) | FC, IP, WB, IHC, FuncS | Human IgG1, κ |
| HPAB-0653-WJ | Mouse Anti-TACSTD2 Recombinant Antibody (HPAB-0653-WJ) | ELISA | Mouse IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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