Recombinant Anti-THY1 Vesicular Antibody, EV Displayed (VS-0425-YC696) (CAT#: VS-0425-YC696)
The Recombinant Anti-THY1 Vesicular Antibody, EV Displayed (VS-0425-YC696) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to THY1-expressed cells or tissues. THY1 is a cell surface glycoprotein involved in cell adhesion, used as a stem cell marker in hematopoietic cells and possibly acting as a tumor suppressor.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3733/992_A2_2_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3733/992_A2_2_selected.jpg
Figure 2 IHC staining of human kidney
(Immunohistochemical staining of human kidney shows moderate membranous positivity in cells in tubules.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68243/ihc_selected.jpg
(Immunohistochemical staining of human kidney shows moderate membranous positivity in cells in tubules.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68243/ihc_selected.jpg
Figure 3 IHC staining of human hippocampus
(Immunohistochemical staining of human hippocampus shows moderate nuclear positivity in neuronal cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68244/ihc_selected.jpg
(Immunohistochemical staining of human hippocampus shows moderate nuclear positivity in neuronal cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68244/ihc_selected.jpg
Figure 4 Cerebral cortex
(Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3733/156319_B_8_5.jpg
(Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3733/156319_B_8_5.jpg
Figure 5 RNA cell line category: Cell line enhanced (ASC diff, BJ, BJ hTERT+, fHDF/TERT166)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000154096-THY1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000154096-THY1
Recombinant Antibody
- Application
- ELISA, FC, Depletion, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- THY1
- Host Animal
- Rabbit
- Antibody Isotype
- IgG
- Species Reactivity
- Dog
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Thy-1 cell surface antigen
- Cellular Localization
- Nucleoplasm, Plasma membrane
- Introduction
- This gene encodes a cell surface glycoprotein and member of the immunoglobulin superfamily of proteins. The encoded protein is involved in cell adhesion and cell communication in numerous cell types, but particularly in cells of the immune and nervous systems. The encoded protein is widely used as a marker for hematopoietic stem cells. This gene may function as a tumor suppressor in nasopharyngeal carcinoma. Alternative splicing results in multiple transcript variants.
- Gene ID
- 489365
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Non-Human Primate (NHP) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1495z-F(E) | Recombinant Anti-Human THY1 Antibody Fab Fragment | FC, WB, FuncS | Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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