Recombinant Anti-Timd4 Vesicular Antibody, EV Displayed (VS-0425-YC706)
CAT#: VS-0425-YC706
The Recombinant Anti-Timd4 Vesicular Antibody, EV Displayed (VS-0425-YC706) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to Timd4-expressed cells or tissues. Timd4 enables phosphatidylserine binding, involved in apoptotic cell clearance, expressed in various tissues like the liver, linked to lupus studies.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A549
Immunofluorescent staining of human cell line A549 shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/15625/1873_G5_4_selected.jpg
Normal Tissue
Figure 2 IHC staining of human lymph node
Immunohistochemical staining of human lymph node shows distinct positivity in macrophages.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/15625/ihc_selected.jpg
Normal Tissue
Figure 3 IHC staining of human tonsil
Immunohistochemical staining of human tonsil shows cytoplasmic positivity in a subset of reaction center cells and lymphoid cells outside reaction centra.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/26027/ihc_selected.jpg
Normal Tissue
Figure 4 Colon
Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/15625/38243_A_7_3.jpg
Normal Tissue
Figure 5 Kidney
Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/15625/38243_A_8_5.jpg
Normal Tissue
Figure 6 Testis
Elongated or late spermatids Staining: Medium Intensity: Moderate Quantity: 75%-25% Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Pachytene spermatocytes Staining: Medium Intensity: Moderate Quantity:>75% Round or early spermatids Staining: Medium Intensity: Moderate Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/15625/38243_A_5_6.jpg
RNA Expression
Figure 7 RNA cell line category: Group enriched (U-266/70, U-266/84)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000145850-TIMD4
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- Timd4
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Mouse
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- T cell immunoglobulin and mucin domain containing 4
- Cellular Localization
- Plasma membrane
- Introduction
- Enables phosphatidylserine binding activity. Acts upstream of or within apoptotic cell clearance. Predicted to be located in membrane. Is expressed in aorta-gonad-mesonephros; brain; gonad; liver; and lung. Used to study systemic lupus erythematosus. Orthologous to human Timd4 (T cell immunoglobulin and mucin domain containing 4).
- Alternative Names
- B430010N18Rik, TIM-4, Tim4
- Gene ID
- 276891
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "Timd4"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2028CQ | Rat Anti-Timd4 Recombinant Antibody (clone RMT4-53) | FC, ICC, IF, Neut | Rat IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2029CQ | Rat Anti-Timd4 Recombinant Antibody (clone RMT4-54) | FC, FuncS, Block | Rat IgG2a, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3571 | Rabbit Anti-Timd4 Recombinant Antibody (clone DS3571AB) | ELISA | Rabbit IgG |
| MOR-4457 | Rabbit Anti-TIMD4 Recombinant Antibody (clone SI551DS) | ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0010-FY | Hamster Anti-TIMD4 Recombinant Antibody (clone Kat5-18) | FC, FuncS, IA, IF | Hamster IgG |
| FAMAB-1302CQ | Mouse Anti-TIMD4 Recombinant Antibody (clone 5G3) | FC, WB, ELISA | Mouse IgG2a |
| FAMAB-1304CQ | Mouse Anti-TIMD4 Recombinant Antibody (clone 3A1) | ELISA, FC | Mouse IgG2a |
| VS3-FY2895 | Mouse Anti-TIMD4 Recombinant Antibody (VS3-FY2895) | WB, FC, ELISA, ICC | Mouse IgG |
| VS7-0425-WR991 | Mouse Anti-TIMD4 Recombinant Antibody (clone 2C6A3) | ICC, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY2292 | Anti-TIMD4 Immunohistochemistry Kit | IHC | |
| VS-0525-XY7259 | Anti-Mouse TIMD4 Immunohistochemistry Kit | IHC |
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